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View Structure Prediction Details

Protein: CAP-PB
Organism: Drosophila melanogaster
Length: 1734 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP-PB.

Description E-value Query
Range
Subject
Range
CAP-PR - The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protei...
599.0 [0..1] [1734..1]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNPIKSAQN SYKNQPGRIE NYTTGHSSVS EKEKKENLEQ SKLSPLYTEG NLSRALAKES  60
   61 GYTSDSNLVF RKKEVPVSSP LSPVEQKQAY KSLQAGGEPP LLGFRKPAPE KPREILEEFE 120
  121 FI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [123-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QITPTLTKIR VSTKELEEEV EPVRKAATPP PAPPPPPPPP PHQSLATSRD HKPVKMFSQL  60
   61 SKNLPSFIPL SKKQQVSQQD DPPPRPPH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [211-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKSSCTKSTV RVLSSASKSR HEQCFQPPNG TAPGVSTITL RKVATSSCSR REPICRSKSA  60
   61 GAVSTLLQTL TATKETRLTR RVQQQQQQSR LRSSSPSRRP ARLLALRHSS RSPVAFGRSI 120
  121 SKERSFAEEK KRLENTLPAN RTNFEASTNI LRDPSLKSPQ EVREAVRSYA TSRSKSLPRL 180
  181 RHTTVSTTTR QTMCFPQVRP QTLLDCGTRS LRKSSSKTGK GQEKNGSNDS LPRSNSTFSI 240
  241 DSMVRQEIVP IAPPKTYVGK SRGSLSKALV PLQNSRSEGH VP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [493-662]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKRQSGKSTT KPPPPVTVHS YSESVREKTN FWNEYNAKQA MSLPQEYKFC PEDVCDFESH  60
   61 TIQQPCIEDL VWKYEGKEQR PPKQVTVTDI ARPQSPQLSQ ERRFSPTREV RVPQISREVR 120
  121 SPSRRRIDSL RSKDKEQSLA RASSLSSADD RKRATPAPSN GLYQCGELAH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [663-1401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SATSLTHLER HSPSCRYRNN CERFTELNRF YSTLERVGQL ERATSSSSFH PLRKDAELLD  60
   61 FDEWRRVRLH ERAEKELQYL VGKLRDDQKQ RDLHFRSKDV DSIKWRQEAD QSLIAKKKSV 120
  121 EDLRENFEQL NLLRQQQQLQ SEPVHRHWRR NTVADLACSL EHQALAEPEM ERHLDNDLVS 180
  181 TLSKDQIKKI TQQLNEIYSG NRHAPAVEEQ YVVTVEKGSR PNGLKVRCNS TISKDQLLGP 240
  241 VQRKRDEQHS NQTLPRSTRS QSPVVVARET RGAIAAKNAE LTLTKPPDVP PRPKPTPSQE 300
  301 IKSKPPPKAE PKVEAREPAE DISQKIQYFE DRQFDEPPKT IYHAREDSSP DEAEVMRLIN 360
  361 QNMQERQRAR QLHHHQELSN SLTDLSGVFG ERPAARVNFH LHSPPDRPPD DTELISFGNG 420
  421 SPDHGDGSLE LYSDSYYRSR SLSPQSQVSA CSSSYLQRVY TGEVRKMRQH FESIQQSGEQ 480
  481 SREPSNERRD FFGLSSLRRA RSDPEMSAGS KDAPDTVTEA VSKEDVPRLT HKFELRAATP 540
  541 SPERGRKRLR SAQDRLMPHI DIISKTAALK RELPIPVRSS PTRSVSSNSH CFERLRMRYE 600
  601 SPEPQTQSYL STSHPDMRDV HDISPHLSAD WVAHKHPEPT KPKDLPKKPQ RVVRASSTSP 660
  661 LRPARSQNHQ LSSRLTSCMK DIFANQKFDP NKHRPKARYV PDGAENGNQK SKDNGTLERL 720
  721 KKTAMVTFKD VNIHFKTPI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 1j7nA
Description: Anthrax toxin lethal factor, N- and C-terminal domains; Anthrax toxin lethal factor, middle domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 0.397873089142268 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [1402-1474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHEQRQNLSE EELAIRQAEH MQKLYHEERR RKYLQELQDM NSRRHTDNFT PSQKSPIALN  60
   61 RYDDFPTDVT LKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 2h8hA
Description: No description for 2h8hA was found.

Predicted Domain #7
Region A:
Residues: [1475-1734]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVGPKTVARA LFNFQGQTSK ELSFRKGDTI YIRRQIDANW YEGEHNAMIG LLPASYVEIV  60
   61 SRDGARTPSK RPSEGQARAK YNFQAQSGIE LSLNKGELVT LTRRVDGNWF EGKIANRKGI 120
  121 FPCSYVEVLT DIGAEDIAAR TTTVITSQST TNLRPNLDVL RTNINNEFNT LTQNGAQPPN 180
  181 GILKETRTLH KTDALHVDTS SEPLAYRALY KYRPQNSDEL ELLEGDVVHV LEKCDDGWFV 240
  241 GTSQRTGCFG TFPGNYVERA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.07557226125735 bayes_pls_golite062009
protein binding 0.974282259959803 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle