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Protein Overview: ssp4-PB

General Information:
Name(s) found: ssp4-PB / FBpp0086105 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene short spindle 4 is referred to in FlyBase by the symbol Dmel\ssp4 (CG33130, FBgn0022085). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13406523..13422942. It has the cytological map location 54C1-54C3. Based on sequence similarity, it is predicted to have molecular function</span>: microtubule binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle elongation; microtubule severing. 8 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1540 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVETQEIRQ ARQRASVKWL LSKAFNNRVP DNLKEPFYRD HENQERLKPQ IIVELGNATL  60
   61 YCQTLANLYS DPNYQSMNHW SIIQTLARKG VPVAESADMP ITETVLIQTN PLRINAHMSV 120
  121 IESLMVLYAK EISSGDRVMA AIRRISGNNY QAPTGQSYEQ ALLGWISHAC AALKKRIIKE 180
  181 VDAGLPDDNG SRLQTPDIPP VRDFQDLCDG ICLALLISYY CPKVVPWTSV RINYLPAVED 240
  241 SIHNILLVCN FSQKHLPYTV MHMTPEDVTY MRGSMKLNLV VLLTDLFNLF EIHPAKCVCY 300
  301 PGMDGQVPHS NSFGGGLNRR STPPNEYQTV QSNNFDGNHA EAFVVHKSRG ITTLASMHSQ 360
  361 QQQQLHQQQQ HQQQYHQQPL QQHPSQSQLQ IQQQEPLVPA RLRQAKEKTN VESKADERGD 420
  421 FVAAGRPSNW EQSRRPSFAG RRSRRNSSSE DSQLTIENFG GSQDQLNTLG RYERDRERKL 480
  481 SNTSVGSYPV EPAVAVRSSI ADARGTLQLG YDTDSGSEKQ DRETEKYSMR RQVSVDNVPT 540
  541 VSSHNLSNAG SPLPVARHKQ HSSDKDYSSN SGMTPDAYND SRSTSGYDPE STPVRKSSTS 600
  601 SMPASPAAWQ LDVGDDDMRS LENASKLSTI RMKLEEKRRR IEQDKRKIEM ALLRHQEKED 660
  661 LESCPDVMKW ETMSNESKRT PDMDPVDLDK YQAYNAPVSA YSSRPPSRDP YQQQLHHQQQ 720
  721 QPMPMPQPMQ YVNEHGQYMS PPQPAHYMPQ QAQQPQSIYS DNGAAYNHSN HSPYGGTPQY 780
  781 RSSVVYDDYG QPTNHFYLHE SSPQPQAHQH PQRRTWAHSA AAAAYEQQQQ IQPSLVDVNA 840
  841 WQTQQHQKQK QTWMNRPPSS AGAPSPGSFM LHQNGGGGGG GGGGGELQHL FQVQASPQHG 900
  901 QRQVSGSNGV QRQQSLTNLR DNRSPKAPQN MGMPMGMPMQ QEDMMAPQSI CFIGDEEDVD 960
  961 ELERNIIESM QSTHISDFVH QQQQQHQHQQ QLQQQQRLQG HSGRGSSSED YDSGEMISNK1020
 1021 LNITSGNLTY RIPSPSRPSI QANSFQDPRA MAAASGGEDQ PPEKGFYISF DDEQPKRPKP1080
 1081 PLRAKRSPKK ESPPGSRDSV DNQATLKRES LSHLHNNNNI GFGNDDVNSK PVTRHSIHGL1140
 1141 NNSNSVKSPG NATYNKYTDE PPIQLRQLAV SGAMSPTSNE RHHLDDVSNQ SPQQTQQPMS1200
 1201 PTRLQQSSNN AEAAKNKALV IGADSTNLDP ESVDEMERRK EKIMLLSLQR RQQQEEAKAR1260
 1261 KEIEASQKRE KEREKEEERA RKKEEQMARR AAILEQHRLK KAIEEAEREG KTLDRPDLHV1320
 1321 KLQSHSSTST TPRLRQQRTT RPRPKTIHVD DASVDISEAS SISSRGKKGS SSNLTDSGLG1380
 1381 RATPPRRAPS PGMGMGASGP KLYKQPAAKS NRGIILNAVE YCVFPGVVNR EAKQKVLEKI1440
 1441 ARSEAKHFLV LFRDAGCQFR ALYSYQPETD QVTKLYGTGP SQVEEVMFDK FFKYNSGGKC1500
 1501 FSQVHTKHLT VTIDAFTIHN SLWQGKRVQL PSKKDMALVI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..301] FFAS03 2.11 Crystal structure of actin-binding domain of mouse plectin
    2 View Details [302..1054] PSI-BLAST 7.0 No description for 1y0fA was found.
    3 View Details [1055..1127] deduced N/A No confident structure predictions are available.
    4 View Details [1128..1457] PSI-BLAST 17.39794 Heavy meromyosin subfragment
    5 View Details [1458..1540] FFAS03 4.54 Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  6.0562477479739 bayes_pls_golite062009
  • microtubule binding
    		•  5.63808442303747 bayes_pls_golite062009
  • tubulin binding
    		•  5.63161872515663 bayes_pls_golite062009
  • actin binding
    		•  5.4843525466095 bayes_pls_golite062009
  • actin filament binding
    		•  3.58546515893973 bayes_pls_golite062009
  • binding
    		•  2.58893177478913 bayes_pls_golite062009
  • protein binding
    		•  2.38389820189848 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  2.34204492212228 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  2.33067686982903 bayes_pls_golite062009
  • dynein binding
    		•  0.282231591450947 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle