Protein Overview: sbb-PE, sbb-PC

General Information:
Name(s) found:	sbb-PE / FBpp0290763 [FlyBase] sbb-PC / FBpp0085945 [FlyBase]
Description(s) found: Found 28 descriptions. SHOW ALL	The gene scribbler is referred to in FlyBase by the symbol Dmel\sbb (CG5580, FBgn0010575). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14166570..14244766. It has the cytological map location 55C2-55C4. There is experimental evidence that it has the molecular function</span>: transcription corepressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of gene-specific transcription from RNA polymerase II promoter; axon guidance; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; axon target recognition; regulation of imaginal disc growth; larval locomotory behavior. 93 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; organ system; nervous system; integumentary plate; thoracic segment; multi-cell-component structure; adult mesothoracic segment; dorsal thoracic disc; unguis. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene scribbler is referred to in FlyBase by the symbol Dmel\sbb (CG5580, FBgn0010575). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14166570..14244766. It has the cytological map location 55C2-55C4. There is experimental evidence that it has the molecular function</span>: transcription corepressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of gene-specific transcription from RNA polymerase II promoter; axon guidance; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; axon target recognition; regulation of imaginal disc growth; larval locomotory behavior. 93 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; organ system; nervous system; integumentary plate; thoracic segment; multi-cell-component structure; adult mesothoracic segment; dorsal thoracic disc; unguis. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	929 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][NAS]
Biological Process:	negative regulation of transcription from RNA polymerase II promoter [NAS] regulation of imaginal disc growth [IMP] photoreceptor cell development [NAS] imaginal disc-derived wing morphogenesis [IMP] axon guidance [IMP][NAS] larval locomotory behavior [IMP][TAS] wing disc dorsal/ventral pattern formation [IGI] axon target recognition [IMP] negative regulation of gene-specific transcription from RNA polymerase II promoter [IMP]
Molecular Function:	transcription factor activity [NAS] zinc ion binding [IEA] transcription corepressor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKKLAKVAL NSSNVATESN IKNNKLLANL SAAGAATATT ATTGTATTTT ATTANQALNF  60
   61 NNKTKATANA TAASANNRHN NNNNSSAIKK HTNTKQLAGK SPACNSSSSS LSSSSSSNSS 120
  121 ESKDTNFEYE DEWNIGGIPE LLDDLDADIE KSAHSSGGGN QATALNAKQA NSSSTSSSSS 180
  181 SKGGASSSSS SAAATGSSSS HKSHKTTLHS NLSATSPTTI KFTRQPVAIG GANSSSSSSA 240
  241 AAAPSGGSAN VVAKGSSSSS SSTSSSSSGK HHHHHHHHSN SSSSGSSSKG YKSALVAQLN 300
  301 SPSPLNSNSK SLSGSGSGSG NTNGAAGAGA GSTLSSSTFA GFSKGGSLVS SSAGAAAALA 360
  361 AGSGQQGSKF SAGGMSSQTG SGSGGNNTSN SNNSSSGSGG SGSGSSTGNT ASGSGNNNST 420
  421 SAGGPPSSQG GNNGNGSGSS SSSSSGKSSA KMSIDHQATL DKGLKMKIKR TKPGTKSSEA 480
  481 KHEIVKATDQ QQNGALGAGS NNSANEDGSS GSSSTNASSL GSTNSSSSAS SGSSSSSGSS 540
  541 SSSSKKHLNN ASSGSGSSSS GGGSQNNASG HASGGGSSGS SQSTPQGTKR GSSGHRREKT 600
  601 KDKNAHSNRM SVDKSAAAAS AAGEKDTPEK CSGTGAGGSP CSCNGDVGAP CSHHACIRRA 660
  661 AHMSNSAGNA NSSAGTGQSG GSSSMSAVPP GVFTPSAGSP STGSPSTVVP AAASLLAATG 720
  721 AASSSASQMA SSSAGGVGGS GGGANAPGPP GKESAGSIKI SSHIAAQLAA AAASNSYSGS 780
  781 GANTNQGQNS NAGGNGGSES KAAAAAQAKL MAPGMISATM HHTISVPAGT GTGDDDTKSP 840
  841 PAKRVKHEAG ASGAGGGKEM VDICIGTSVG TITEPDCLGP CEPGTSVTLE GIVWHETEGG 900
  901 VLVVNVTWRG KTYVGTLLDC TRHDWAPPR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..182]	deduced	N/A	No confident structure predictions are available.
2	View Details	[183..424]	deduced	N/A	No confident structure predictions are available.
3	View Details	[425..545]	deduced	N/A	No confident structure predictions are available.
4	View Details	[546..609]	deduced	N/A	No confident structure predictions are available.
5	View Details	[610..684]	deduced	N/A	No confident structure predictions are available.
6	View Details	[685..843]	deduced	N/A	No confident structure predictions are available.
7	View Details	[844..929]	deduced	N/A	No confident structure predictions are available.

Protein Overview: sbb-PE, sbb-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: