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Protein Overview: Adf1-PC

General Information:
Name(s) found: Adf1-PC / FBpp0089262 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Adh transcription factor 1 is referred to in FlyBase by the symbol Dmel\Adf1 (CG15845, FBgn0000054). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2549774..2555592. It has the cytological map location 42C3. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: synapse assembly; locomotion; dendrite morphogenesis; memory. 54 alleles are reported. The phenotypes of these alleles are annotated with: intersegmental nerve; bouton. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 262 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS][NAS]
    Biological Process: long-term memory [TAS]
    synapse assembly [IMP]
    locomotion [IMP]
    larval locomotory behavior [NAS]
    positive regulation of transcription [TAS]
    olfactory learning [NAS]
    memory [IMP]
    regulation of transcription from RNA polymerase II promoter [NAS]
    learning or memory [NAS]
    dendrite morphogenesis [IMP]
    Molecular Function: DNA binding [IEA]
    RNA polymerase II transcription factor activity [NAS]
    general RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTLTAAIEM DKLDANLEQQ FDLNLIEAVK LNPVIYDRSH YNYKHFVRKA QTWKQIAETL  60
   61 GVPEQKCTKR WKSLRDKFAR EMKLCQESRW RYFKQMQFLV DSIRQYRESL LGKCANGSQS 120
  121 ANQVADPSQQ QQAQQQTVVD IFAQPFNGSA TTSAQALTHP HEITVTSDAQ LATAVGKDQK 180
  181 PYFYEPPLKR ERSEEEHSDN MLNTIKIFQN NVSQAVSAED QSFGMVVTDM LNTLGVRQKA 240
  241 EAKVHIIKYL TDMQLLAQHN KY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..262] FFAS03 0.989 DNA-binding domain of rap1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle