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Protein Overview: Ptr-PA, FBpp0298...

General Information:
Name(s) found: FBpp0298836 [FlyBase]
FBpp0298835 [FlyBase]
Ptr-PA / FBpp0085347 [FlyBase]
Description(s) found:
Found 33 descriptions.
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  • type=protein; loc=2R:complement(2070015..2071853,2071914..2072227,2072785..2073123,2073189..2073352,2073412..2073591,2073660..2073841,2073980..2074194,2076590..2076735,2076796..2076926); ID=FBpp0298836; name=Ptr-PC; parent=FBgn0262867,FBtr0307501; dbxref=REFSEQ:NP_001246146,GB_protein:AFH07901,FlyBase:FBpp0298836,FlyBase_Annotation_IDs:CG11212-PC; MD5=6dbbfc27929785cec585adcf9b01e725; length=1169; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:complement(2070015..2071853,2071914..2072227,2072785..2073123,2073189..2073352,2073412..2073591,2073660..2073841,2073980..2074194,2076590..2076735,2076796..2076926); ID=FBpp0298835; name=Ptr-PB; parent=FBgn0262867,FBtr0307500; dbxref=REFSEQ:NP_001246145,GB_protein:AFH07900,FlyBase:FBpp0298835,FlyBase_Annotation_IDs:CG11212-PB; MD5=6dbbfc27929785cec585adcf9b01e725; length=1169; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ptc-related is referred to in FlyBase by the symbol Dmel\Ptr (CG11212, FBgn0033068). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2069480..2083512. It has the cytological map location 42A13. It is reported to have molecular function</span>: receptor activity. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles is annotated with: larval central nervous system. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1169 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    plasma membrane [ISS]
    Biological Process: NONE FOUND
    Molecular Function: hedgehog receptor activity [IEA]
    receptor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTCGISCVDK TLNKSFYHLG ICIAKHPGYF IIIPVLLTLL CMTGYQQLKY QIDPEYLFSP  60
   61 IAGEGKTERA IVEQYFKVNY THRFNVGRIT RPGRFGRVIV ITKDGDENMI RREVFQELRQ 120
  121 LDNIIQNATT TYDGDTYTYK DNCARWENEC FENDILNLDA LMDDIEAGQL NLTFPFMFNP 180
  181 VTWDAHLFPV FFGGTKLTED NYVISVPAIQ LVYFVTADTK RQDAKGAEWE ETFLRVVGNA 240
  241 ENSGQFKHIS VSYFASRTLD HELEKNTKTV VPYFSSTFLL MGLFSIITCM MGDAVRSKPF 300
  301 LGLMGNVSAI MATLAAFGLA MYCGIEFIGI NLAAPFLMIG IGIDDTFVML AGWRRTKAKM 360
  361 PVAERMGLMM SEAAVSITIT SVTDFISFLI GIISPFRSVR IFCTYSVFAV CFTFLWHITF 420
  421 FAACMAISGY RERKNLHSIF GCRVQPMSVA IKEKRNFLYK AIMAGGIDAN DPDNPIDNKD 480
  481 HMLMAFFKDK MAAVINNKWC KAIIILAFAS YLVGACYGIT QIKEGLERRK LSREDSYSVE 540
  541 FFDREDDYYR EFPYRMQVII AGPLNYSDPL VQEQVENLTS TLEHTSYVTS RRYTESWLRS 600
  601 FLSFLERNNE LLNVTVDDEQ TFIDAVKEHW LFPGNPFSLD VRFNEDETQI IASRFLIQAV 660
  661 NITDTNHEKE MVRDLRQICK DSPLNASIFH PYFVFFDQFE LVRPVSLQAM VIGAIIMMII 720
  721 SFVFIPNILC SLWVAFSVIS IELGVAGYMA LWDVNLDSIS MINLIMCIGF SVDFTAHICY 780
  781 TYMSSKKRSP KARVREALHS LGLPIIQGSS STILGIVALL LAQSYIFLVF FKMVFLVIFF 840
  841 GAMHGLFLLP VLLSLFGPGS CLTWTGKDDG SDAEVDDGLD DRQLEKPFSQ SYYMQYPSIG 900
  901 INGPYGSKGF LGAPYKAYGV DEKDLGLGTS GEDSSESSSS RSQHRQQAAA TEEEVVVRES 960
  961 PTRRYDDGWR RSSYQNIYGQ GAAQFQAQPD LYGKQVSATE WRQRLDTHEQ QQRQRQRRSP1020
 1021 FENYRQDVEI DMQKARRNSH GDVIDLHGTP NSSVEERFRR RGEPFSAESG DDSSYRHQQI1080
 1081 MAMPAAGSAP SAKRYHRRRS SEDSTSRHQR WPANIEERRA RRAYSPAHNR PETALTSYAY1140
 1141 RSSSHHNLYQ PNGKSSKYPP TYQYGDYYH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] deduced N/A No confident structure predictions are available.
    2 View Details [199..372] deduced N/A No confident structure predictions are available.
    3 View Details [373..1169] PSI-BLAST 152.0 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains; Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains; Multidrug efflux transporter AcrB transmembrane domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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