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View Structure Prediction Details

Protein: Ptr-PA, FBpp0298...
Organism: Drosophila melanogaster
Length: 1169 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ptr-PA, FBpp0298....

Description E-value Query
Range
Subject
Range
gi|167645301, gi... - gi|167645301|ref|YP_001682964.1| hydrophobe/amphiphile efflux-1 (HAE1) family protein [Caulobacter s...
546.0 [0..375] [1168..11]

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Predicted Domain #1
Region A:
Residues: [1-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTCGISCVDK TLNKSFYHLG ICIAKHPGYF IIIPVLLTLL CMTGYQQLKY QIDPEYLFSP  60
   61 IAGEGKTERA IVEQYFKVNY THRFNVGRIT RPGRFGRVIV ITKDGDENMI RREVFQELRQ 120
  121 LDNIIQNATT TYDGDTYTYK DNCARWENEC FENDILNLDA LMDDIEAGQL NLTFPFMFNP 180
  181 VTWDAHLFPV FFGGTKLT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [199-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDNYVISVPA IQLVYFVTAD TKRQDAKGAE WEETFLRVVG NAENSGQFKH ISVSYFASRT  60
   61 LDHELEKNTK TVVPYFSSTF LLMGLFSIIT CMMGDAVRSK PFLGLMGNVS AIMATLAAFG 120
  121 LAMYCGIEFI GINLAAPFLM IGIGIDDTFV MLAGWRRTKA KMPVAERMGL MMSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [373-1169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAVSITITSV TDFISFLIGI ISPFRSVRIF CTYSVFAVCF TFLWHITFFA ACMAISGYRE  60
   61 RKNLHSIFGC RVQPMSVAIK EKRNFLYKAI MAGGIDANDP DNPIDNKDHM LMAFFKDKMA 120
  121 AVINNKWCKA IIILAFASYL VGACYGITQI KEGLERRKLS REDSYSVEFF DREDDYYREF 180
  181 PYRMQVIIAG PLNYSDPLVQ EQVENLTSTL EHTSYVTSRR YTESWLRSFL SFLERNNELL 240
  241 NVTVDDEQTF IDAVKEHWLF PGNPFSLDVR FNEDETQIIA SRFLIQAVNI TDTNHEKEMV 300
  301 RDLRQICKDS PLNASIFHPY FVFFDQFELV RPVSLQAMVI GAIIMMIISF VFIPNILCSL 360
  361 WVAFSVISIE LGVAGYMALW DVNLDSISMI NLIMCIGFSV DFTAHICYTY MSSKKRSPKA 420
  421 RVREALHSLG LPIIQGSSST ILGIVALLLA QSYIFLVFFK MVFLVIFFGA MHGLFLLPVL 480
  481 LSLFGPGSCL TWTGKDDGSD AEVDDGLDDR QLEKPFSQSY YMQYPSIGIN GPYGSKGFLG 540
  541 APYKAYGVDE KDLGLGTSGE DSSESSSSRS QHRQQAAATE EEVVVRESPT RRYDDGWRRS 600
  601 SYQNIYGQGA AQFQAQPDLY GKQVSATEWR QRLDTHEQQQ RQRQRRSPFE NYRQDVEIDM 660
  661 QKARRNSHGD VIDLHGTPNS SVEERFRRRG EPFSAESGDD SSYRHQQIMA MPAAGSAPSA 720
  721 KRYHRRRSSE DSTSRHQRWP ANIEERRARR AYSPAHNRPE TALTSYAYRS SSHHNLYQPN 780
  781 GKSSKYPPTY QYGDYYH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 152.0
Match: 1oy6A
Description: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains; Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains; Multidrug efflux transporter AcrB transmembrane domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle