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Protein Overview: CG6036-PA

General Information:
Name(s) found: CG6036-PA / FBpp0084399 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6036 (CG6036, FBgn0039421). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:22170053..22171187. It has the cytological map location 97A9. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. It is reported to be involved in the biological process</span>: protein amino acid dephosphorylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 371 amino acids

    Gene Ontology:
    Cellular Component: protein serine/threonine phosphatase complex [IEA]
    Biological Process: protein amino acid dephosphorylation [IEA][NAS]
    Molecular Function: protein serine/threonine phosphatase activity [ISS][NAS]
    magnesium ion binding [IEA]
    manganese ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGHKMGGFLE KPETEKQAQE GHGNGLRYCV SSMQGWRLEM EDSHSAACRL KDPFATWSYF  60
   61 AVFDGHAGSQ ISLHCAEHLM STILESESFS KHKYEAGIRE GFLQLDEDMR KLYHDQQGGS 120
  121 TAICVFVSPD KIYLVNCGDS RAVISRNGAA VISTIDHKPF SPKEQERIQN AGGSVMIKRI 180
  181 NGTLAVSRAF GDYDFKNDGS KSPVDQMVSP EPDIIVCNRS EHDEFIVVAC DGIWDVMTSS 240
  241 EVCEFIRSRL LVTYDLPMIV NSVLDICLHK GSRDNMTLLL LLLPGAPKVD MDAVKAERSL 300
  301 DQTIVQITKE VIEKHEIHDF ETLIRLMKRM AINIPNLPPG GGLYAKYYII EQAFHEKFPD 360
  361 TPAEIYDYFS M

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..371] PSI-BLAST 98.09691 CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.29765002420868 bayes_pls_golite062009
  • phosphatase activity
    		•  6.46633224572308 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.25564034681743 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  6.20846750257603 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.62997267604309 bayes_pls_golite062009
  • hydrolase activity
    		•  2.93014592649821 bayes_pls_golite062009
  • binding
    		•  1.74689317666387 bayes_pls_golite062009
  • signal transducer activity
    		•  1.61688496161233 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.61688496161233 bayes_pls_golite062009
  • catalytic activity
    		•  1.53401212718168 bayes_pls_golite062009
  • protein binding
    		•  1.47578617076714 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle