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Protein Overview: CG4836-PB

General Information:
Name(s) found: CG4836-PB / FBpp0083236 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4836 (CG4836, FBgn0038762). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15839594..15843976. It has the cytological map location 92C1. Based on sequence similarity, it is predicted to have molecular function</span>: L-iditol 2-dehydrogenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 2 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1214 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: oxidation reduction [IEA]
    Molecular Function: zinc ion binding [IEA]
    L-iditol 2-dehydrogenase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLFGRVTNI LQISRCVSYH APLYRPRSLL HAERLRQLCT SASSGSKSSR RTNHPCRVRV  60
   61 QRYSQKGSNV FSVSDNVDML RKRISFSGNS SNAPKIMPIG LITPETGDGK DLKIVIVPLD 120
  121 LSGMDGNELK DTLETINKLR LYANHIETFS NSMVEEYGAL NEALQEVESG GQPQEVKAGA 180
  181 SAEDRKFWEA FPSTPTADAV GTALDAGQGA NMPMQRQTAV NSCLQNAVGN SAINSALKTT 240
  241 KSMSAMAQTE PIHGSTKASN LQELANQESD FVEEVRVDVP QDLSNRLNDM AVSSMELSFE 300
  301 MDMTNLRQAL ESKDKNAVTP QDPMICMHTK VELDAPGTVE KTLPLRFNAL ISGVVEIDTQ 360
  361 KLSPAQITED KMPGFNDDLT SLAANLCSTA LEKGFAGKSS DTYIADLELT KDEETIPNRI 420
  421 IDTSHMSAAN QVGQVRESLQ KIAEEACAMP GIQEQEVPVP VDKDGCKHPP VKPKRKCPGK 480
  481 CPLITDPCKE DPCERPAKKK APKKKALKTT EITCKGKGGG KSACGKDKKK DPCGKKDTKK 540
  541 KDPCAKFKSG EKKDPCAKKK DPCAKKKADP CAKKKADPCA KKKKDPCAKK KADPCAKKKK 600
  601 DPCAKKKADP CAKKKKDPCA KKKADPCAKK KSSCAKKDDK KKDPCAKFKK GGSGGKSKCK 660
  661 FSTVANLPDA SRRHLSTALS QAFRESNSVS NGPRFKVYST LVRRHYRVPV PKIESSCQCS 720
  721 LCTSRLLHKA VAPARFTINT ALMRRRFGGL AGRISGGALQ HISYRGYAKK SKSGGKCGEL 780
  781 QTKYPINRGK DIKERTGLRE DCFSDEDSCP KKSCTGKCAK VKFPKKKCDR KKKKDGNLLT 840
  841 RSSIAQLQPQ RRSFSTRPCC HPSSEKRTAD DEALTLRITN PYEISVVPFS KPRPKDFDVL 900
  901 IRTGSVAVSN SDIHVYENGN RDMEAMSLGH DATGIVEELG RCVQHLHVGD RVVMESALSC 960
  961 GICDLCKKGL YNMCSGLVYN GFLSTYQTHP ADLCHRLPES ISMEAGALTQ TLALGCQACF1020
 1021 KANVTPTSNV LILGACPTAV AAGICAKAIG AKRVAIAGCM APALDVVARD FGFQAVEFDS1080
 1081 NALFGEVLEA IYSKFRDWPD CVINCSISAM TMNLAVMALQ PCGVCVLAEC DSECASFNAL1140
 1141 DVLMKNIRLV PSFRSANMYP TALQLMQSGR AHMQKFITAT YPLSKADEAF RAAQHESNIG1200
 1201 LGKVIVNCAE EVDV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] deduced N/A No confident structure predictions are available.
    2 View Details [110..248] MSA 1.157994 View MSA. No confident structure predictions are available.
    3 View Details [249..400] MSA 2.190996 View MSA. No confident structure predictions are available.
    4 View Details [401..635] MSA 2.198995 View MSA. No confident structure predictions are available.
    5 View Details [636..867] deduced N/A No confident structure predictions are available.
    6 View Details [868..1214] PSI-BLAST 104.0 Ketose reductase (sorbitol dehydrogenase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • L-iditol 2-dehydrogenase activity
    		•  3.00103406168296 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  2.94416173750168 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  2.26153457113968 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.69771604880532 bayes_pls_golite062009
  • chaperone binding
    		•  0.484522928331397 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.418775403210681 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.39817482511246 bayes_pls_golite062009
  • L-arabinitol 2-dehydrogenase activity
    		•  0.382131941157781 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.32207755075663 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle