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Protein Overview: FBpp0307208, SdhC-PA

General Information:
Name(s) found: FBpp0307208 [FlyBase]
SdhC-PA / FBpp0081848 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • type=protein; loc=3R:complement(7034949..7035462,7035520..7035521); ID=FBpp0307208; name=SdhC-PB; parent=FBgn0037873,FBtr0335221; dbxref=REFSEQ:NP_001262472,GB_protein:AGB95854,FlyBase:FBpp0307208,FlyBase_Annotation_IDs:CG6666-PB; MD5=8c1677c5a126026444aaef707cb0e8b2; length=171; release=r5.56; species=Dmel; [FlyBase]
  • The gene Succinate dehydrogenase C is referred to in FlyBase by the symbol Dmel\SdhC (CG6666, FBgn0037873). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7034856..7035571. It has the cytological map location 86D7-86D8. Based on sequence similarity, it is predicted to have molecular function</span>: succinate dehydrogenase activity; succinate dehydrogenase (ubiquinone) activity. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; response to oxidative stress; mitochondrial electron transport, succinate to ubiquinone. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 171 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex II [ISS]
    Biological Process: response to oxidative stress [IMP]
    determination of adult lifespan [IMP]
    mitochondrial electron transport, succinate to ubiquinone [IMP][ISS]
    tricarboxylic acid cycle [ISS]
    succinate metabolic process [ISS]
    Molecular Function: succinate dehydrogenase (ubiquinone) activity [ISS]
    electron carrier activity [IEA]
    succinate dehydrogenase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYALSSSLIR SPALRQGLQM AAASRPVSMK VVSVAETQKD ESFFEKNERL GRELSPHLTI  60
   61 YQPQLTSMLS ICHRGTGLAL GVGVWGLGLG ALISSHDISH YVTMVEGLQL SGATLTALKF 120
  121 IIAYPAGYHT ANGIRHLLWD TGRFLKIKEV YSTGYAMVAT SFVLSAILAL L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] PSI-BLAST 39.154902 Crystal Structure of Mitochondrial Respiratory Complex II from porcine heart at 2.4 Angstroms


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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