Protein Overview: MRP-PL

General Information:
Name(s) found:	MRP-PL / FBpp0089067 [FlyBase]
Description(s) found: Found 18 descriptions. SHOW ALL	The gene Multidrug-Resistance like Protein 1 is referred to in FlyBase by the symbol Dmel\MRP (CG6214, FBgn0032456). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12719071..12744809. It has the cytological map location 33F3-33F4. There is experimental evidence that it has the molecular function</span>: ATPase activity, coupled to movement of substances; ATPase activity, coupled to transmembrane movement of substances. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 5 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1548 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA]
Biological Process:	transmembrane transport [IEA]
Molecular Function:	ATP binding [IEA] ATPase activity, coupled to transmembrane movement of substances [IDA] ATPase activity, coupled to movement of substances [IDA] xenobiotic-transporting ATPase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADDTSSPMD RFCGSTFWNA TETWYTNDPD FTPCFEQTAL VWTPCAFYWA FVIFDFYYLK  60
   61 ASLDRNIPWN KLNVSKALVN LGLLVITALD LIMALVKKGG DSELPLYDLD VWGPIIKFAT 120
  121 FLLLFIFIPL NRKYGVQTTG CQFIFWFLLT VLSIPRCRTE VRLDAERQKI LNSQQPSEQD 180
  181 FSWEEYQFVS FFIFFTFTSI MLILNCFADG MPRQTKYQRG ENEIPELSAS FLSRITYQWF 240
  241 DKMALKGYRN PLEEKDLWDL RPQDSCSEVM PIFAHHWNQN VRKNYKNKAR VEPKAQFSNG 300
  301 NVTFENPHGE KNGRKKGMAS IMPPIYKSFG GVFLFGALMK LFTDTLTFAQ PQVLSLIISF 360
  361 VEAQDAEPEW KGILYAVLLF VLAAAQTFIL GQYFHRMFIV GLRIRTALIN AIYRKALRIS 420
  421 NSTKKESTVG EIVNLMAVDA QRFMELTTYL NMIWSAPLQI GLALYFLWQQ LGPSVLAGLA 480
  481 VMIILIPVNG VIASRIKTYQ IRQMKYKDER VKLMNEVLSG IKVLKLYAWE PSFEKQVLDI 540
  541 RDKEIATLRS TAYLNAGTSF LWSCAPFLVS LVTFATYVLI DENNVLDATK TFVSLSLFNI 600
  601 LRFPLTMLPM LITNLVQTQV SVNRINKFLN SEELDPNSVL HDSSKPHPMS IENGEFSWGD 660
  661 EITLRNINIE VKKGSLVALV GTVGSGKSSV VQAFLGEMEK LAGVVNTVGK LAYVPQQAWI 720
  721 QNATVRDNIL FGQTYDRKRY NKVIDACALR ADIDILSAGD LTEIGEKGIN LSGGQKQRIS 780
  781 LARAVYSDAD LYLLDDPLSA VDAHVGKHIF EEVIGPKGIL ARKSRVLVTH GVTFLPQVDS 840
  841 IYVIKMGEIS ESGTFDQLVK NKGAFADFII QHLQEGNEEE EELNQIKRQI SSTADVPELL 900
  901 GTVEKAIKLA RTESLSDSIS VTSADSLMGG GGSLRRRTKR QDSHDSVASA ASLKKKQEVE 960
  961 GKLIETEKSQ TGGVEFAVYK HYIKSVGIFL SVATLVLNFV FQAFQIGSNL WLTQWANDQN1020
 1021 VANDTGLRDM YLGVYGAFGF GQGLCNYGAA ISLFTATLHA SSRVFHRLFN NIMHCPSEFF1080
 1081 DTTPKGRILD RCSSDVNCLD LVMPLNIRMV MSTAFQVLAT IVVISLSTPI FLAVIVPIAF1140
 1141 LYYFAQRFYV ATSRQLMRLE SVSRSPIYSH FSETVTGAST IRAYNVGDRF IEESDAKVDK1200
 1201 NQVCKYPSVI ANRWLAIRLE MVGNLIILFA SLFAVLGGQT NPGLVGLSVS YALQVTQTLN1260
 1261 WLVRMSSDIE TNIVSVERIK EYGETKQEAP WELEQDKNKP KNWPQEGRVE FQNFQVRYRE1320
 1321 GLDLVLRGVS FNIQGGEKVG IVGRTGAGKS SLTLALFRII EAAGGRISID GVDIASMGLH1380
 1381 MLRSRLTIIP QDPVLFSGSL RINLDPFEIK TDDEIWKALE LSHLKSFVKS LAAGLNHEIA1440
 1441 EGGENLSVGQ RQLVCLARAL LRKTKVLVLD EATAAVDLET DDLIQKTIRT EFKECTVLTI1500
 1501 AHRLNTILDS DKVIVLDKGQ IIEFASPTEL LDNPKSAFYS MAKDANLV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: MRP-PL

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: