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Protein Overview: asl-PA

General Information:
Name(s) found: asl-PA / FBpp0078392 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene asterless is referred to in FlyBase by the symbol Dmel\asl (CG2919, FBgn0261004). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1428949..1432244. It has the cytological map location 83B4-83B5. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: centrosome organization; sensory perception of mechanical stimulus; centrosome cycle; sperm axoneme assembly; centriole replication; sensory cilium assembly; single fertilization. 12 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; intracellular organelle part; male germline cyst; anatomical structure; cytoskeletal part; elongation stage spermatid; cytoplasmic part; adult segment; spindle; thoracic segment; centrosome. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 994 amino acids

    Gene Ontology:
    Cellular Component: microtubule basal body [IDA]
    pericentriolar material [IDA]
    centrosome [IDA]
    centriole [IDA]
    Biological Process: sensory cilium assembly [IMP]
    centrosome cycle [IMP]
    centrosome organization [IMP]
    centriole replication [IMP]
    sperm axoneme assembly [IMP]
    sensory perception of mechanical stimulus [IMP]
    single fertilization [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTPGISLFQ GADALNINST LDRQEEEEAL QDQKRREEEL GRIMVNAFDD LLDEENTIDS  60
   61 TTNYQSELEQ PPVLPNYPSH PHHKPLQDDA QRANEIEMHR LQILLESKNN ELQNVNQVAN 120
  121 AAHKKLDDLQ KHLSIMQAEL DRAIREKQNT HELLVETKET CSNKDSDLDK LRSEKKQLEE 180
  181 DNTRLVGQLE AAKTLLTDVQ SKYDMVQASK QKWEERNADL RLKQMEEAHR AQSDLLQQQL 240
  241 CQMKDQLDRK QNELDQINSR YNALQSGHET MLVDKAAKIN ELSQALDEAQ MRCNQLSARP 300
  301 DLQAENRRQQ QCIVDLKARI AYLEQTVASL HERLNETTTE LDLIDSVIQQ HQADESPTSR 360
  361 LSQMGGSRLV GSTPLNPLDR VGHIKQELYR ALGNLKNKRE EVRRLEKLLE ERNQELRVLR 420
  421 DQENQSLVQL ETLNEGKMRL ENKVKAMQQE LEEQKHRSQQ ESDVHSQLNS IVAERDALRE 480
  481 KRQQIEEDLE QLKQQNESLQ RNYDQLSQEN RQLRTRETAD NLRLELERHK ILLRDSQSEV 540
  541 ERLKKLYSDI ATDKESLGYE LRKLRESDTL KELQDQRQNL ATVQRNLQLA EMKSEELKKL 600
  601 LETEKLSHER DLQALRQRSE REKREEAVAV AKESSENCSK CIESIAEITK AEIQLLKLQN 660
  661 VNSMQAKELK ELEHALEQSK NLQAEMQEKI ELSNKQDELI SDLKERAKQF EAYIRQQEEH 720
  721 KQQNKCTPSP KSNSVSPSDP SPKELTQNRI RLIEQRVRDE MAKLFAAELK RFTNRLQKSE 780
  781 ERSQCLQREY QTVCAELQQR QTEVDLLKQT ILAERENIDE ILAGREEKQK EMLQKCRQEL 840
  841 QAKNQRIAEL LREVEEQHAS IDSERQSMKA VMAQWEKQRQ SVDQVEHHWR QQLESLRSTH 900
  901 EEAMRSAQQR YQSAKRTAHN YKLYAEDKEA HMKREYERIK HEYELSLAKI EATMNQHLER 960
  961 RSREKHRDKE NVPSNSSSDP ITNSNRKPKG NGHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..295] PSI-BLAST 17.0 Heavy meromyosin subfragment
    2 View Details [296..371] PSI-BLAST 9.09691 Tropomyosin
    3 View Details [372..901] FFAS03 0.971 alpha-actinin
    4 View Details [902..994] FFAS03 0.99 Structure of Unphosphorylated STAT1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.230804607057959 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle