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Protein Overview: Nle-PA

General Information:
Name(s) found: Nle-PA / FBpp0077735 [FlyBase]
Description(s) found:
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  • gi|45549090|ref|NP_477294.2| notchless [Drosophila melanogaster] [NCBI NR]
  • gi|45445001|gb|AAF51479.2| notchless [Drosophila melanogaster] [NCBI NR]
  • gi|19527819|gb|AAL90024.1| AT08344p [Drosophila melanogaster] [NCBI NR]
  • Protein Notchless OS=Drosophila melanogaster GN=Nle PE=1 SV=2 [Swiss-Prot]
  • The gene Notchless is referred to in FlyBase by the symbol Dmel\Nle (CG2863, FBgn0021874). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:566366..568162. It has the cytological map location 21E2. It is reported to have molecular function</span>: Notch binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: Notch signaling pathway. 7 alleles are reported. The phenotype of these alleles is annotated with: microchaeta. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • (AAF51479) CG2863-PA [DrosMelano7227.FASTAC.txt]
  • CG2863-PA [Drosophila melanogaster]gi|19527819|gb|AAL90024.1| AT08344p [Drosophila melanogaster]gi|45549090|ref|NP_477294.2| CG2863-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:complement(566426..566438,566498..566624,566680..567030,567089..568064); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF5147 [fly-100309-contam.fasta]
  • CG2863-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Notchless CG2863-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • AT08344p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:complement(566426..566438,566498..566624,566680..567030,567089..568064); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF51479.2,REFSEQ:NP_477294,GB_protein:AAF51479; MD5=3a11af53f9bd81f7da87f71ff603b318; length=488; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(566426..566438,566498..566624,566680..567030,567089..568064); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF51479.2,REFSEQ:NP_477294,GB_protein:AAF51479; MD5=3a11af53f9bd81f7da87f71ff603b318; length=488; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • AT08344p OS=Drosophila melanogaster GN=Nle PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:complement(566426..566438,566498..566624,566680..567030,567089..568064); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF51479.2,REFSEQ:NP_477294,GB_protein:AAF51479,FlyMine:FBpp0077735,modMine:FBpp0077735; MD5=3a11af53f9bd81f7da87f71ff603b318; length=488; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • AT08344p OS=Drosophila melanogaster GN=Nle PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2L:complement(join(567089..568064,566680..567030,566498..566624,566426..566438)); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF51479.2,REFSEQ:NP_477294,GB_protein:AAF51479,FlyMine:FBpp0077735,modMine:FBpp0077735; MD5=3a11af53f9bd81f7da87f71ff603b318; length=488; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(567089..568064,566680..567030,566498..566624,566426..566438)); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF51479.2,REFSEQ:NP_477294,GB_protein:AAF51479,FlyMine:FBpp0077735,modMine:FBpp0077735; MD5=3a11af53f9bd81f7da87f71ff603b318; length=488; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0077735 type=protein; loc=2L:complement(join(567089..568064,566680..567030,566498..566624,566426..566438)); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF51479.2,REFSEQ:NP_477294,GB_protein:AAF51479,FlyMine:FBpp0077735,modMine:FBpp0077735; MD5=3a11af53f9bd81f7da87f71ff603b318; length=488; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:complement(join(567089..568064,566680..567030,566498..566624,566426..566438)); ID=FBpp0077735; name=Nle-PA; parent=FBgn0021874,FBtr0078075; dbxref=GB_protein:AAF51479.1,FlyBase:FBpp0077735,FlyBase_Annotation_IDs:CG2863-PA,GB_protein:AAF51479.2,REFSEQ:NP_477294,GB_protein:AAF51479,UniProt/Swiss-Prot:Q9VPR4,FlyMine:FBpp0077735,modMine:FBpp0077735; MD5=3a11af53f9bd81f7da87f71ff603b318; length=488; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: Notch signaling pathway [ISS][TAS]
    Molecular Function: Notch binding [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAKKQKMQE TDTEQEATPH TIQARLVSDT GEEAGPPIDL PAGITTQQLG LICNALLKNE  60
   61 EATPYLFFVG EDEIKKSLED TLDLASVDTE NVIDIVYQPQ AVFKVRPVTR CTSSMPGHAE 120
  121 AVVSLNFSPD GAHLASGSGD TTVRLWDLNT ETPHFTCTGH KQWVLCVSWA PDGKRLASGC 180
  181 KAGSIIIWDP ETGQQKGRPL SGHKKHINCL AWEPYHRDPE CRKLASASGD GDCRIWDVKL 240
  241 GQCLMNIAGH TNAVTAVRWG GAGLIYTSSK DRTVKMWRAA DGILCRTFSG HAHWVNNIAL 300
  301 STDYVLRTGP FHPVKDRSKS HLSLSTEELQ ESALKRYQAV CPDEVESLVS CSDDNTLYLW 360
  361 RNNQNKCVER MTGHQNVVND VKYSPDVKLI ASASFDKSVR LWRASDGQYM ATFRGHVQAV 420
  421 YTVAWSADSR LIVSGSKDST LKVWSVQTKK LAQELPGHAD EVFGVDWAPD GSRVASGGKD 480
  481 KVIKLWAY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle