Protein Overview: Sema-5c-PA

General Information:
Name(s) found:	Sema-5c-PA / FBpp0075784 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45550455\|ref\|NP_611293.3\| Semaphorin-5c [Drosophila melanogaster] [NCBI NR] gi\|45445917\|gb\|AAF49966.3\| Semaphorin-5c [Drosophila melanogaster] [NCBI NR] The gene Semaphorin-5c is referred to in FlyBase by the symbol Dmel\Sema-5c (CG5661, FBgn0250876). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12060611..12074927. It has the cytological map location 68F2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: receptor activity. There is experimental evidence that it is involved in the biological process</span>: startle response; brain morphogenesis; olfactory behavior; embryonic development via the syncytial blastoderm; locomotion involved in locomotory behavior; central complex development. 14 alleles are reported. The phenotypes of these alleles are annotated with: ellipsoid body; mushroom body alpha-lobe. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] (AAF49966) CG5661-PA [DrosMelano7227.FASTAC.txt] CG5661-PA [Drosophila melanogaster]gi\|45550455\|ref\|NP_611293.3\| CG5661-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(12061235..12061453,12061510..12061712,12061779..12061934,12061999..12062909,12063018..12063824,12063899..12064101,12064165..12064296,12064687..12064860,12064964..12065171,12073041..12073140,12073895..12074058,12074447..1207 [fly-100309-contam.fasta] CG5661-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Sema-5c CG5661-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(12061235..12061453,12061510..12061712,12061779..12061934,12061999..12062909,12063018..12063824,12063899..12064101,12064165..12064296,12064687..12064860,12064964..12065171,12073041..12073140,12073895..12074058,12074447..12074451); ID=FBpp0075784; name=Sema-5c-PA; parent=FBgn0250876,FBtr0076052; dbxref=GB_protein:AAF49966.3,GB_protein:AAF49966.2,FlyBase:FBpp0075784,FlyBase_Annotation_IDs:CG5661-PA,REFSEQ:NP_611293,GB_protein:AAF49966; MD5=2dae16459566d4f7596ad1f1cf98e3a8; length=1093; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(12061235..12061453,12061510..12061712,12061779..12061934,12061999..12062909,12063018..12063824,12063899..12064101,12064165..12064296,12064687..12064860,12064964..12065171,12073041..12073140,12073895..12074058,12074447..12074451); ID=FBpp0075784; name=Sema-5c-PA; parent=FBgn0250876,FBtr0076052; dbxref=GB_protein:AAF49966.3,GB_protein:AAF49966.2,FlyBase:FBpp0075784,FlyBase_Annotation_IDs:CG5661-PA,REFSEQ:NP_611293,GB_protein:AAF49966; MD5=2dae16459566d4f7596ad1f1cf98e3a8; length=1093; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Semaphorin-5c, isoform A OS=Drosophila melanogaster GN=Sema-5c PE=1 SV=3 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(12061235..12061453,12061510..12061712,12061779..12061934,12061999..12062909,12063018..12063824,12063899..12064101,12064165..12064296,12064687..12064860,12064964..12065171,12073041..12073140,12073895..12074058,12074447..12074451); ID=FBpp0075784; name=Sema-5c-PA; parent=FBgn0250876,FBtr0076052; dbxref=GB_protein:AAF49966.3,GB_protein:AAF49966.2,FlyBase:FBpp0075784,FlyBase_Annotation_IDs:CG5661-PA,REFSEQ:NP_611293,GB_protein:AAF49966,FlyMine:FBpp0075784,modMine:FBpp0075784; MD5=2dae16459566d4f7596ad1f1cf98e3a8; length=1093; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] Semaphorin-5c, isoform A OS=Drosophila melanogaster GN=Sema-5c PE=2 SV=3 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:complement(join(12081347..12081351,12080795..12080958,12079941..12080040,12071864..12072071,12071587..12071760,12071065..12071196,12070799..12071001,12069918..12070724,12068899..12069809,12068679..12068834,12068410..12068612,12068135..12068353)); ID=FBpp0075784; name=Sema-5c-PA; parent=FBgn0250876,FBtr0076052; dbxref=GB_protein:AAF49966.3,GB_protein:AAF49966.2,FlyBase:FBpp0075784,FlyBase_Annotation_IDs:CG5661-PA,REFSEQ:NP_611293,GB_protein:AAF49966,FlyMine:FBpp0075784,modMine:FBpp0075784; MD5=2dae16459566d4f7596ad1f1cf98e3a8; length=1093; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(12081347..12081351,12080795..12080958,12079941..12080040,12071864..12072071,12071587..12071760,12071065..12071196,12070799..12071001,12069918..12070724,12068899..12069809,12068679..12068834,12068410..12068612,12068135..12068353)); ID=FBpp0075784; name=Sema-5c-PA; parent=FBgn0250876,FBtr0076052; dbxref=GB_protein:AAF49966.3,GB_protein:AAF49966.2,FlyBase:FBpp0075784,FlyBase_Annotation_IDs:CG5661-PA,REFSEQ:NP_611293,GB_protein:AAF49966,FlyMine:FBpp0075784,modMine:FBpp0075784; MD5=2dae16459566d4f7596ad1f1cf98e3a8; length=1093; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Semaphorin-5c, isoform A OS=Drosophila melanogaster GN=Sema-5c PE=4 SV=3 [DROME.fasta.20160308] FBpp0075784 type=protein; loc=3L:complement(join(12081347..12081351,12080795..12080958,12079941..12080040,12071864..12072071,12071587..12071760,12071065..12071196,12070799..12071001,12069918..12070724,12068899..12069809,12068679..12068834,12068410..12068612,12068135..12068353)); ID=FBpp0075784; name=Sema-5c-PA; parent=FBgn0250876,FBtr0076052; dbxref=GB_protein:AAF49966.3,GB_protein:AAF49966.2,FlyBase:FBpp0075784,FlyBase_Annotation_IDs:CG5661-PA,REFSEQ:NP_611293,GB_protein:AAF49966,FlyMine:FBpp0075784,modMine:FBpp0075784; MD5=2dae16459566d4f7596ad1f1cf98e3a8; length=1093; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(12081347..12081351,12080795..12080958,12079941..12080040,12071864..12072071,12071587..12071760,12071065..12071196,12070799..12071001,12069918..12070724,12068899..12069809,12068679..12068834,12068410..12068612,12068135..12068353)); ID=FBpp0075784; name=Sema5c-PA; parent=FBgn0284221,FBtr0076052; dbxref=GB_protein:AAF49966.3,GB_protein:AAF49966.2,FlyBase:FBpp0075784,FlyBase_Annotation_IDs:CG5661-PA,REFSEQ:NP_611293,GB_protein:AAF49966,UniProt/TrEMBL:Q9VTT0,FlyMine:FBpp0075784,modMine:FBpp0075784; MD5=2dae16459566d4f7596ad1f1cf98e3a8; length=1093; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1093 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [ISS]
Biological Process:	locomotion involved in locomotory behavior [IMP] embryonic development via the syncytial blastoderm [IEP] startle response [IMP] central complex development [IMP] axon guidance [ISS] brain morphogenesis [IMP] olfactory behavior [IMP]
Molecular Function:	receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMLILKLPK MFSQLWLLLI LSLLTLEGPQ PSTGSGYTTK SSVDLLENDS RYISYQDLMS  60
   61 TAKRFYDPET TWYSEMLFDV ARNQVIVGAR DTLYRMSFDL EPLERASWGA TPSEIAMCQA 120
  121 KGQSERWCRN YVRVLHSYGE NQLYACGTNA FQPSCSWRQM ENLTVTGVDS GVVKCPFHPQ 180
  181 ANSTSLLQSN GQLFVGTATD FSGSDVAILR TGVESNKRFL RTKQYNNNWL SGAQFVGSFE 240
  241 AGHFVYFLLR ESAAEHMSCG KVIYSRVARV CKNDVGGGGQ LLRDNWTSFL KARLNCSLPG 300
  301 EYPYYFDEIQ GMTYAESESI LYATFRTSGS SIFGSAVCAY NLSSINAAFD GPFKQQEHSD 360
  361 AAWKTVNTNQ RSQFQCGTSS IGHWLESSRY QLMDEAVQPI GAEPLYHSKL EQFGRLALDI 420
  421 INTKTEQVHV LFVASSGNHI KKLSVKYDGD GVQTCLVELW QADDTGTSSL LNMAYLKVSD 480
  481 SLYLGTDLAL TRIPAQHCSR HVSQSSCLNS MDPYCGWNEL VERCMPQPQD SSVLQHWHQA 540
  541 PQITCPVLNA PIDGGWSTWS PWAVCQQHEQ PDSNCQCRQR SCNNPQPQHG GATCEGISTQ 600
  601 VTNCTQHGGW TEWSAWSPCS QTCGIAVKIR RRTCGNPRPA FGGRTCVGSE QSEMYCRHLP 660
  661 PCPVAKPQSV DGGWGPWGEW SECSAQCGGG FRMRRRECND PAPLNGGMEC PGCRLDYEEC 720
  721 NMQSCQEVRK LSAWTPWLTV TGSGNSSEPH MERRFRFVCR ATSPDPSSVR IGLPKEESRN 780
  781 CHADGSCQRQ VDHDSADSDA ADWSPCSVSC GGGVQQRHRG RGSQSRVCNI HACPAEEQLS 840
  841 SNSLDNELEH GEWGCWSEWS ACSVTCGLGL RRRTRRCLAG HDRLCQGRAL EEQKCEMVPC 900
  901 EDFLGWSAWS EWSSCSSDGI RLRHRRCLVE QPGSMECRGA EFEKTACVPN ECEETQTAST 960
  961 ATLPIVIFVG LLFTVACCLA TYRFTKKRFM LSAEEALNKT TTTTASFDTY PNQYSSLPTK1020
 1021 DYYDQRPKRQ SSFRMPAKTS NLGNGNGTLN RNNMHQNNTP KVLAKTYIDC ESGTIKRQSA1080
 1081 LNNCRSNIDD EKF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Sema-5c-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: