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Protein Overview: FBpp0309970, FBp...

General Information:
Name(s) found: FBpp0309970 [FlyBase]
FBpp0298030 [FlyBase]
FBpp0298029 [FlyBase]
RhoGAP16F-PB / FBpp0074287 [FlyBase]
Description(s) found:
Found 43 descriptions.
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  • type=protein; loc=X:join(17989298..17990486,17990549..17990654,17990724..17990910); ID=FBpp0309970; name=RhoGAP16F-PF; parent=FBgn0030893,FBtr0343310; dbxref=FlyBase:FBpp0309970,FlyBase_Annotation_IDs:CG7122-PF; MD5=48f5589ec6c96cccfdd4d8f77c0942a3; length=493; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:join(17989298..17990486,17990549..17990654,17990724..17990910); ID=FBpp0298030; name=RhoGAP16F-PD; parent=FBgn0030893,FBtr0307201; dbxref=REFSEQ:NP_573267,GB_protein:AAF48798,FlyBase:FBpp0298030,FlyBase_Annotation_IDs:CG7122-PD; MD5=48f5589ec6c96cccfdd4d8f77c0942a3; length=493; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:join(17989298..17990486,17990549..17990654,17990724..17990910); ID=FBpp0298029; name=RhoGAP16F-PC; parent=FBgn0030893,FBtr0307200; dbxref=REFSEQ:NP_001245730,GB_protein:AFH07443,FlyBase:FBpp0298029,FlyBase_Annotation_IDs:CG7122-PC; MD5=48f5589ec6c96cccfdd4d8f77c0942a3; length=493; release=r5.56; species=Dmel; [FlyBase]
  • The gene RhoGAP16F is referred to in FlyBase by the symbol Dmel\RhoGAP16F (CG7122, FBgn0030893). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17987194..17991450. It has the cytological map location 16F6. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: signal transduction. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 493 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: signal transduction [IEA]
    Molecular Function: GTPase activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTTTSQRPV TPGTPDSAHI VIGAAGFVAH ERRQPGKTLM NCFRDRSTTS SSSSQAQHAY  60
   61 VRGHSVTSST LFRLEGSGGS NCTLDKAGKQ DTGRPEAVVL LRELKTRPNK LALLKSSSSK 120
  121 DLTRLFLDDS TNTAVLVSNT SIDVCSSNSS SGGSPAVGRS KSGRDRRNGL ECCSSCSKRW 180
  181 HDLKQRMHTL EQDLLVQTTY SQELEQKVGE MSRQLTELLQ ERDRERDKDK ARFAAAGGVA 240
  241 APGKRTAHGS PNVRPSRLVA WMNLSNWFKS RPSVETLREQ RIFFDEPCFD TELEMVLKHD 300
  301 QHRTVPRIVV DCCDLIEQKY RRSTQPIEGI YRQCGDYNKI QTLRFSIDAN DYDSLRQPDV 360
  361 DIHTLTGVLK LFLREIKSPL VRVNEAKTFI GQPNQWLLTD LSAKLDSLKR LIRSLPESNR 420
  421 DTMDYIFGHF NRITKVPLQQ ISAETLSISV TPSIFHTVPQ GVHMQDIQQL LREGETLADC 480
  481 VKLMIEYQGR IFE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..146] MSA 1.247992 View MSA. No confident structure predictions are available.
    2 View Details [147..493] PSI-BLAST 56.39794 Crystal Structure of the Human Beta2-Chimaerin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • enzyme activator activity
    		•  0.53004209819211 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.528693496432149 bayes_pls_golite062009
  • binding
    		•  0.0980674097362609 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  0.0454578418356197 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle