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View Structure Prediction Details

Protein: FBpp0309970, FBp...
Organism: Drosophila melanogaster
Length: 493 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309970, FBp....

Description E-value Query
Range
Subject
Range
gi|114666638, gi... - gi|114666640|ref|XP_511570.2| PREDICTED: similar to CIN85-associated multi-domain containing RhoGAP ...
284.0 [0..3] [492..350]

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Predicted Domain #1
Region A:
Residues: [1-146]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTTTSQRPV TPGTPDSAHI VIGAAGFVAH ERRQPGKTLM NCFRDRSTTS SSSSQAQHAY  60
   61 VRGHSVTSST LFRLEGSGGS NCTLDKAGKQ DTGRPEAVVL LRELKTRPNK LALLKSSSSK 120
  121 DLTRLFLDDS TNTAVLVSNT SIDVCS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [147-493]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSSSGGSPA VGRSKSGRDR RNGLECCSSC SKRWHDLKQR MHTLEQDLLV QTTYSQELEQ  60
   61 KVGEMSRQLT ELLQERDRER DKDKARFAAA GGVAAPGKRT AHGSPNVRPS RLVAWMNLSN 120
  121 WFKSRPSVET LREQRIFFDE PCFDTELEMV LKHDQHRTVP RIVVDCCDLI EQKYRRSTQP 180
  181 IEGIYRQCGD YNKIQTLRFS IDANDYDSLR QPDVDIHTLT GVLKLFLREI KSPLVRVNEA 240
  241 KTFIGQPNQW LLTDLSAKLD SLKRLIRSLP ESNRDTMDYI FGHFNRITKV PLQQISAETL 300
  301 SISVTPSIFH TVPQGVHMQD IQQLLREGET LADCVKLMIE YQGRIFE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.39794
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme activator activity 0.53004209819211 bayes_pls_golite062009
GTPase activator activity 0.528693496432149 bayes_pls_golite062009
binding 0.0980674097362609 bayes_pls_golite062009
Ras GTPase activator activity 0.0454578418356197 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle