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Protein Overview: Sep4-PG

General Information:
Name(s) found: Sep4-PG / FBpp0074145 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • The gene Septin 4 is referred to in FlyBase by the symbol Dmel\Sep4 (CG9699, FBgn0259923). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16578244..16589206. It has the cytological map location 15A1-15A2. It is reported to have molecular function</span>: GTPase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytokinesis. 9 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 375 amino acids

    Gene Ontology:
    Cellular Component: septin complex [IEA]
    septin ring [ISS]
    Biological Process: cytokinesis [ISS][NAS]
    cell cycle [IEA]
    Molecular Function: GTP binding [IEA]
    protein binding [IEA]
    GTPase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKTPSFDKD RDYIGFATLP EQVHRKSVKR GFEFTLMVVG ESGLGKSTLI NSLFLGDLYK  60
   61 NRQMPNVEER IEKTTKVEKK TMDIEERGVR LRLTVVDTPG FGDAINCEDS WRVCTQYIDE 120
  121 QFRQYFTDES GLNRRNIQDN RVHCCLYFVP PWGHSLRQMD LDLIRRLHRK VNIVLVIGKA 180
  181 DCLNKQEVRK LKERILQDLE DNHIQLYQFP ECDSDEDDDF KQQDRELKAS IPFAVVGSNT 240
  241 ILEVAGKKVR GRQYPWGVVN VEDPEHSDFI KLRTFLISTH MQDLKDTTQD VHYENFRAQC 300
  301 ISQISQHALR ERGKLKRDSI SSTNGFDAAI SETDRLLLQK DEEIRRMQDM LTQMQEKLKQ 360
  361 THLMEMKKND SVIDV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..375] PSI-BLAST 88.0 No description for 2qagA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle