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Protein Overview: Vrp1-PE

General Information:
Name(s) found: Vrp1-PE / FBpp0071709 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • The gene Verprolin 1 is referred to in FlyBase by the symbol Dmel\Vrp1 (CG13503, FBgn0243516). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17994243..18010053. It has the cytological map location 58B8-58B9. There is experimental evidence that it has the molecular function</span>: actin filament binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; myoblast fusion; actin filament organization; positive regulation of actin filament polymerization. 13 alleles are reported. The phenotype of these alleles is annotated with: embryonic myoblast. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 761 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    filopodium tip [IDA]
    Biological Process: regulation of cell shape [IMP]
    positive regulation of actin filament polymerization [IDA]
    myoblast fusion [IMP][NAS]
    actin filament organization [IMP]
    Molecular Function: actin filament binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLKRSSKQK MAIPPPPGPP PPPGPPPPPA MGGLKLGGAG GADARSALLS SIQKGTKLKK  60
   61 TTTVDKSGPA LSGKVCGGDG GAGIGAKRTL NNNTSTSNHN NSSSSSNGLG NGTPKLGGLF 120
  121 EGLSQMPKLK PVNGIRATPS AGSAATTTSK STTNSSAQQR SNSPPAATSA SNASNGPMDF 180
  181 NTELTKHLTL KRQKQQQQQQ PQPPTNNTHI NATEANLRTN RGPPPQPPKS ANSNDSILER 240
  241 MNIPRTAPTP PFGNSSSVKA ASPTLSDSGS NSSGSGGGSG SVKSKAANLN ISLGNSFVNS 300
  301 SKSTVSASTA SLNSSLTSST GSVRNLAPNK STLFGGSSGS SSGSSSGGGY ASVHKSSPPS 360
  361 TADSTPSVTP TPPPLQLPMK PAISFGKPNF APKPPGLNQL AMANGQQRPA VTRHHSMKSP 420
  421 RSPPAAGIVN GLVFPTQQHL GTLRGPLQFH GSESSSPNTS AGSMRCAPNP PKSRPSVKPP 480
  481 PPPTPARSFS NTNLNNIGGS TMFSAVNTAL IQSSAISSQA PSPPITQPPS SSSSSNSVAA 540
  541 LRDQFRGGAG MSNGAPSPPL PPTPAPSSNP SSASASPKSL LRDNVKPIIL NGGPLNPPAP 600
  601 PPHRSCPPPP PPQRQSSNQD RVKYWIDKTV YSFKKILHIN RQGRHSGESV KVINMLNSKR 660
  661 NGGSGSGSAP VPPQRHSSIR PNAPSTPPTH MANASHQFGS SSGLSSGSGA GAAASVGRLV 720
  721 NDLETKFGKR FHNVTEFPKP PPFLNIQKVY PSRTFKATNG M

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] deduced N/A No confident structure predictions are available.
    2 View Details [141..297] deduced N/A No confident structure predictions are available.
    3 View Details [298..409] deduced N/A No confident structure predictions are available.
    4 View Details [410..525] MSA 3.149985 View MSA. No confident structure predictions are available.
    5 View Details [526..761] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle