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Protein Overview: ASPP-PA

General Information:
Name(s) found: ASPP-PA / FBpp0071548 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein is referred to in FlyBase by the symbol Dmel\ASPP (CG18375, FBgn0034606). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17105361..17138458. It has the cytological map location 57D2-57D4. There is experimental evidence that it has the molecular function</span>: protein tyrosine kinase activator activity. The biological processes in which it is involved are not known. 14 alleles are reported. The phenotypes of these alleles are annotated with: eye; interommatidial bristle; wing; ommatidium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1020 amino acids

    Gene Ontology:
    Cellular Component: adherens junction [IDA]
    Biological Process: NONE FOUND
    Molecular Function: protein tyrosine kinase activator activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEPTNTLDE IVPSRLTSAE LRAMALRQQQ QIDSQHQLLA TKEQRLRFLK SQEVRSAVAS  60
   61 AEGERLRRLR ERVEAQESKL RRLRALRGQV DLQKTYNVTL SNDLDSIRAL FSEKEKELSL 120
  121 AVAKVEALTR QLEELRRDRR CPVNILTAAG NGVGGQSLPP QASRELEKLR RELMYRNQLS 180
  181 LQQDARLHMQ REALQQRQAE LRSTDQRIYE LQTRLQRKKQ ANTHHQQQQQ QQQQHQQQQH 240
  241 QQQHQQTTVQ QQQQQQQQLH VQSAQLLAAA AAATAQQQQQ HQQHQQQQQQ QQQQSASNLG 300
  301 KHGGVAALKQ QLLQKQVNQL AAAAAAAAAG RARGNVAAVE PFIHTPQKST ITSTASYLSG 360
  361 GMKHAAATAN TNQQNQLIQD LTHVKLGQNS GFFAGSVPVP VASSSCESDE SKLAKKLLAA 420
  421 PAKTEAELRK QAQTEAMDST THIYAEVGPK KRDREAAAAA AAAAAAAAAA AQAAAEAANQ 480
  481 AATAAAASAI SPPATANASK IPKSTTSSSS SASALISKLN QQATAKESQD QQQSQAKKNE 540
  541 ISVTSETLSE RNTQQQLTVH SMPLGAISKS VALAVSNASK PLQVQVSNVA VPPRKPISSV 600
  601 APNSVSSGSS IPKMITYSPK VNRVAPNVVM TDPRPALPPK PSKMSPTEQP SPVEANTSGS 660
  661 AGGAGSGAAS ASTANKTQTA TFGLQSLNIN DNLPIKAKPL TIRKQPLFEQ PRLKSSQSSS 720
  721 NGQQKPPLLQ LQNQRKSEPS ARQPTENLPD TSPQHSPSSE SSADETDRMV APSITTSQQE 780
  781 TSTSATSTTT TVTTSNIKER TGNGKPKLGR RVSFDPLALL LDASLEGELE LVKKTAMQVA 840
  841 NPSAANDEGI TALHNAICAG HIDIVKFLVE FGCDVNAQDS DGWTPLHCAA SCNNLSMVKF 900
  901 LVESGACLFA STLSDHETPA EKCEEDEEGF DGCSEYLYSI QEKLGILHNG DVYAVFSYEA 960
  961 QNGDELSFHV NEPLIVLRKG DDAENEWWWA RNAAGEEGYV PRNLLGLYPR VPPHSPHFSD1020
 1021

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..302] PSI-BLAST 21.0 Heavy meromyosin subfragment
    2 View Details [303..500] deduced N/A No confident structure predictions are available.
    3 View Details [501..621] deduced N/A No confident structure predictions are available.
    4 View Details [622..689] deduced N/A No confident structure predictions are available.
    5 View Details [690..826] PSI-BLAST 12.221849 Crystal structure of UPLC1 GAP domain
    6 View Details [827..1020] PSI-BLAST 40.522879 53BP2


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

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