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View Structure Prediction Details

Protein: ASPP-PA
Organism: Drosophila melanogaster
Length: 1020 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASPP-PA.

Description E-value Query
Range
Subject
Range
gi|115926458 - gi|115926458|ref|XP_001180763.1| PREDICTED: similar to ankyrin 2,3/unc44 [Strongylocentrotus purpura...
535.0 [0..284] [1019..198]

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Predicted Domain #1
Region A:
Residues: [1-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEPTNTLDE IVPSRLTSAE LRAMALRQQQ QIDSQHQLLA TKEQRLRFLK SQEVRSAVAS  60
   61 AEGERLRRLR ERVEAQESKL RRLRALRGQV DLQKTYNVTL SNDLDSIRAL FSEKEKELSL 120
  121 AVAKVEALTR QLEELRRDRR CPVNILTAAG NGVGGQSLPP QASRELEKLR RELMYRNQLS 180
  181 LQQDARLHMQ REALQQRQAE LRSTDQRIYE LQTRLQRKKQ ANTHHQQQQQ QQQQHQQQQH 240
  241 QQQHQQTTVQ QQQQQQQQLH VQSAQLLAAA AAATAQQQQQ HQQHQQQQQQ QQQQSASNLG 300
  301 KH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [303-500]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGVAALKQQL LQKQVNQLAA AAAAAAAGRA RGNVAAVEPF IHTPQKSTIT STASYLSGGM  60
   61 KHAAATANTN QQNQLIQDLT HVKLGQNSGF FAGSVPVPVA SSSCESDESK LAKKLLAAPA 120
  121 KTEAELRKQA QTEAMDSTTH IYAEVGPKKR DREAAAAAAA AAAAAAAAAQ AAAEAANQAA 180
  181 TAAAASAISP PATANASK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [501-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPKSTTSSSS SASALISKLN QQATAKESQD QQQSQAKKNE ISVTSETLSE RNTQQQLTVH  60
   61 SMPLGAISKS VALAVSNASK PLQVQVSNVA VPPRKPISSV APNSVSSGSS IPKMITYSPK 120
  121 V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [622-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRVAPNVVMT DPRPALPPKP SKMSPTEQPS PVEANTSGSA GGAGSGAASA STANKTQTAT  60
   61 FGLQSLNI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [690-826]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDNLPIKAKP LTIRKQPLFE QPRLKSSQSS SNGQQKPPLL QLQNQRKSEP SARQPTENLP  60
   61 DTSPQHSPSS ESSADETDRM VAPSITTSQQ ETSTSATSTT TTVTTSNIKE RTGNGKPKLG 120
  121 RRVSFDPLAL LLDASLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 2b0oE
Description: Crystal structure of UPLC1 GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [827-1020]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GELELVKKTA MQVANPSAAN DEGITALHNA ICAGHIDIVK FLVEFGCDVN AQDSDGWTPL  60
   61 HCAASCNNLS MVKFLVESGA CLFASTLSDH ETPAEKCEED EEGFDGCSEY LYSIQEKLGI 120
  121 LHNGDVYAVF SYEAQNGDEL SFHVNEPLIV LRKGDDAENE WWWARNAAGE EGYVPRNLLG 180
  181 LYPRVPPHSP HFSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.522879
Match: 1ycsB
Description: 53BP2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle