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Protein Overview: mip130-PA

General Information:
Name(s) found: mip130-PA / FBpp0070302 [FlyBase]
Description(s) found:
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  • gi|60678099|gb|AAX33556.1| LD07342p [Drosophila melanogaster] [NCBI NR]
  • gi|55926022|gb|AAV68084.1| Myb-interacting protein 130 [Drosophila melanogaster] [NCBI NR]
  • gi|45549300|ref|NP_569958.2| Myb-interacting protein 130 [Drosophila melanogaster] [NCBI NR]
  • gi|45446779|gb|AAF45694.3| Myb-interacting protein 130 [Drosophila melanogaster] [NCBI NR]
  • The gene Myb-interacting protein 130 is referred to in FlyBase by the symbol Dmel\mip130 (CG3480, FBgn0023509). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1802246..1814351. It has the cytological map location 2B15-2B16. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: centrosome organization; mitotic spindle organization; negative regulation of transcription from RNA polymerase II promoter. 11 alleles are reported. The phenotype of these alleles is annotated with: chorion. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • (AAF45694) CG3480-PA [DrosMelano7227.FASTAC.txt]
  • CG3480-PA [Drosophila melanogaster]gi|45549300|ref|NP_569958.2| CG3480-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(1802386..1802388,1811010..1813967); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protei [fly-100309-contam.fasta]
  • Myb-interacting protein 130 CG3480-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD07342p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Myb-interacting protein 130 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG3480-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(1802386..1802388,1811010..1813967); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protein:AAF45694; MD5=ca555accfbe42677215714a92457f36d; length=986; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(1802386..1802388,1811010..1813967); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protein:AAF45694; MD5=ca555accfbe42677215714a92457f36d; length=986; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • LD07342p OS=Drosophila melanogaster GN=mip130 PE=1 SV=3 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(1802386..1802388,1811010..1813967); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protein:AAF45694,FlyMine:FBpp0070302,modMine:FBpp0070302; MD5=ca555accfbe42677215714a92457f36d; length=986; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • LD07342p OS=Drosophila melanogaster GN=mip130 PE=2 SV=3 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=X:join(1908353..1908355,1916977..1919934); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protein:AAF45694,FlyMine:FBpp0070302,modMine:FBpp0070302; MD5=ca555accfbe42677215714a92457f36d; length=986; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(1908353..1908355,1916977..1919934); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protein:AAF45694,FlyMine:FBpp0070302,modMine:FBpp0070302; MD5=ca555accfbe42677215714a92457f36d; length=986; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0070302 type=protein; loc=X:join(1908353..1908355,1916977..1919934); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protein:AAF45694,FlyMine:FBpp0070302,modMine:FBpp0070302; MD5=ca555accfbe42677215714a92457f36d; length=986; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(1908353..1908355,1916977..1919934); ID=FBpp0070302; name=mip130-PA; parent=FBgn0023509,FBtr0070315; dbxref=GB_protein:AAF45694.3,GB_protein:AAF45694.2,FlyBase:FBpp0070302,FlyBase_Annotation_IDs:CG3480-PA,REFSEQ:NP_569958,GB_protein:AAF45694,UniProt/TrEMBL:Q9W542,FlyMine:FBpp0070302,modMine:FBpp0070302; MD5=ca555accfbe42677215714a92457f36d; length=986; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 986 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][NAS]
    polytene chromosome [IDA]
    cytoplasm [NAS]
    Myb complex [IDA]
    chromatin [IDA]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMP]
    eggshell chorion gene amplification [IC]
    centrosome organization [IMP]
    mitotic spindle organization [IMP]
    Molecular Function: DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTGRPVRMS VAVNQKGWGK KAGASVSDSA IRTQSALSEG GGAIDVRPME HDEEINREDL  60
   61 NLDEDDEMEE EEEEEHADEE DDDEEPDSNE NSAPEEQVEP PAFSLATLGL QRVGSAPPPK 120
  121 PKVQKAPIPT LNARGMPARI RKRNRLFYDE NIINDDKPLR MSLAPKKTPG RPPQSAGGGS 180
  181 SQKIPLTPSK VLKKRKGVVS RYMRSSEQGT NSVSASNQPQ LLGKHKKATP SKSQSVGSKL 240
  241 GSGGPKTGRG AHFIGKGTAA AVAAVAAAEE EANQAEAAAL ANKRLGQSIG LRLRNLLKLP 300
  301 KAHKWAIAEW FYSYVDKPLF ECRDEFMNHV NELAPRLGTR SLIRHEWVNI RRRMGRPRRC 360
  361 SAKFFSEERK ELDRKRQVIR TLQSRKPGEF KDSVSMLSDM PEKIPMTLPL GTKVTARLRS 420
  421 PQDGIFAGTV AAYDSLNAMY RVTFERIGLG THAIPDYEIV SENFHEMLPL HSFTKDFRPN 480
  481 LMSIYQTNNL GFTTNLGFTA NLTNNYLQKK EKIDGGAGAA AGAGSLYFKP QKHLATNNAA 540
  541 ARNALSMKLN KSDPLLGQDS VGVSPIRQQL TRNRGYSTSL LEHLVRLEKY IAVKADRIQR 600
  601 LNKMNGTAEL AMGDMISHDE NGDRHRRQIA VNFQRQYAFN IVTIERINAE LMFELTKVQE 660
  661 LSSSLTRNPN VQAMISPTYL REECRAKASQ TVDDINKGMV KNTRMIKLLK DLTTLLIVTQ 720
  721 NLGGDCEVSE VNEVLEGCLE EVRSNLICSE NREVFQMSVQ GRLEYIAMDI SRRLEEKSLS 780
  781 RVADGDDDIK SLKSEDETDE DHVQDHKHGA DEEPAADTSK TKAKGSPKQV EGKENSEVDK 840
  841 MDHSSHPMDT DTEKEEKLES GGSENAGYAS QQRQDEDQDT EEQHLDLEEQ HLDPEEHHLD 900
  901 LEEQHLDPEE QHLDLEEHHL ELEEQHLDPE EQSLNPAVTE DTQITIESMK ESDEEFQSAA 960
  961 ETEEDDMVGL IMEEEEEEEF VYDKDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..315] deduced N/A No confident structure predictions are available.
    2 View Details [316..468] Pfam 72.769551 No description for PF06584.4 was found. No confident structure predictions are available.
    3 View Details [469..568] deduced N/A No confident structure predictions are available.
    4 View Details [569..906] PSI-BLAST 10.30103 Heavy meromyosin subfragment
    5 View Details [907..986] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle