Protein Overview: Acon-PC

General Information:
Name(s) found:	Acon-PC / FBpp0111768 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|161076999\|ref\|NP_001097186.1\| aconitase, isoform C [Drosophila melanogaster] [NCBI NR] gi\|157400191\|gb\|ABV53697.1\| aconitase, isoform C [Drosophila melanogaster] [NCBI NR] The gene Aconitase is referred to in FlyBase by the symbol Dmel\Acon (CG9244, FBgn0010100). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:21168356..21173017. It has the cytological map location 39A7. Based on sequence similarity, it is predicted to have molecular function</span>: aconitate hydratase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: tricarboxylic acid cycle. 20 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] (Q9VIE8) CG9244 protein [DrosMelano7227.FASTAC.txt] (AE003669) Acon gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta] type=protein; loc=2L:join(21170470..21171828,21171895..21172398,21172460..21172648); ID=FBpp0111768; name=Acon-PC; parent=FBgn0010100,FBtr0112855; dbxref=FlyBase:FBpp0111768,FlyBase_Annotation_IDs:CG9244-PC,REFSEQ:NP_001097186,GB_protein:ABV53697; MD5=0c7 [fly-100309-contam.fasta] type=protein; loc=2L:join(21170470..21171828,21171895..21172398,21172460..21172648); ID=FBpp0111768; name=Acon-PC; parent=FBgn0010100,FBtr0112855; dbxref=FlyBase:FBpp0111768,FlyBase_Annotation_IDs:CG9244-PC,REFSEQ:NP_001097186,GB_protein:ABV53697; MD5=0c77709e4d1a0b7ab254eb9b561607a6; length=683; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(21170470..21171828,21171895..21172398,21172460..21172648); ID=FBpp0111768; name=Acon-PC; parent=FBgn0010100,FBtr0112855; dbxref=FlyBase:FBpp0111768,FlyBase_Annotation_IDs:CG9244-PC,REFSEQ:NP_001097186,GB_protein:ABV53697; MD5=0c77709e4d1a0b7ab254eb9b561607a6; length=683; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Aconitase, isoform C OS=Drosophila melanogaster GN=Acon PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
Organism:	Drosophila melanogaster
Length:	683 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] mitochondrion [ISS][NAS]
Biological Process:	tricarboxylic acid cycle [IEA]
Molecular Function:	4 iron, 4 sulfur cluster binding [IEA] aconitate hydratase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDATAQMAL LQFISSGLKK VAVPSTVHCD HLIEAQIGGP KDLARAKDLN KEVYDFLAST  60
   61 CAKYGLGFWK PGSGIIHQII LENYAFPGLL MIGTDSHTPN GGGLGGLCIG VGGADAVDVM 120
  121 ADIPWELKCP KVIGVNLTGK ISGWTSPKDV ILKVADILTV KGGTGAIIEY HGKGVDSISC 180
  181 TGMATICNMG AEIGATTSLF PFNQRMADYL KSTGRAGIAS EAQKYQAKIL SADKNCEYDE 240
  241 LIEINLDTLE PHVNGPFTPD LGHPISKLGE NSKKNGYPMD IRVGLIGSCT NSSYEDMGRC 300
  301 ASIAKDAMSH GLKSKIPFNV TPGSEQIRAT IERDGISEVF DKFGGTVLAN ACGPCIGQWD 360
  361 RKDVKKGDKN TIVTSYNRNF TGRNDANPAT HCFVTSPELV TALSIAGRLD FNPLTDELTG 420
  421 ADGKKFKLKA PFGDELPAKG FDPGQDTYTA PPPSGENVKV AVDPKSTRLQ LLEPFDKWNG 480
  481 QDLTDLTVLI KVKGKCTTDH ISAAGPWLKY RGHLDNISNN MFIGATNYEN NEMNNIKNQR 540
  541 NGSWGGVPDV ARDYKANGIK WVAVGDENYG EGSSREHAAL EPRHLGGRAI IVKSFARIHE 600
  601 TNLKKQGLLP LTFANPADYD KIQPTSKISL LNLKSLAPGK PVDAEIKNGD KVERIKLNHT 660
  661 LNDLQIGWFK AGSALNRMKE LAQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.89

Protein Overview: Acon-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: