Protein Overview: MTRF1

General Information:
Name(s) found:	MTRF1 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|62512140\|sp\|O75570.2\|RF1M_HUMAN RecName: Full=Peptide chain release factor 1, mitochondrial; AltName: Full=MRF-1; Flags: Precursor [NCBI NR] gi\|55958420\|emb\|CAI16615.1\| mitochondrial translational release factor 1 [Homo sapiens] [NCBI NR] gi\|34577120\|ref\|NP_004285.2\| mitochondrial translational release factor 1 [Homo sapiens] [NCBI NR] gi\|27503783\|gb\|AAH42196.1\| Mitochondrial translational release factor 1 [Homo sapiens] [NCBI NR] gi\|119629058\|gb\|EAX08653.1\| mitochondrial translational release factor 1, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119629056\|gb\|EAX08651.1\| mitochondrial translational release factor 1, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119629054\|gb\|EAX08649.1\| mitochondrial translational release factor 1, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119629053\|gb\|EAX08648.1\| mitochondrial translational release factor 1, isoform CRA_a [Homo sapiens] [NCBI NR] mitochondrial translational release factor 1 [HGNC (HUGO)] Peptide chain release factor 1, mitochondrial OS=Homo sapiens GN=MTRF1 PE=1 SV=2 [Swiss-Prot] mitochondrial translational release factor 1; mitochontrial peptide chain release factor 1 [HMR_022704.fasta] mitochondrial translational release factor 1 [Homo sapiens]gi\|27503783\|gb\|AAH42196.1\| Mitochondrial translational release factor 1 [Homo sapiens] [nrdb_11152004_Chlamydomonas] Peptide chain release factor 1, mitochondrial precursor (MRF-1) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Peptide chain release factor 1, mitochondrial precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] mitochondrial translational release factor 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Mitochondrial translational release factor 1 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta] mitochondrial translational release factor 1; mitochontrial peptide chain release factor 1 [Homo sapiens] [HumanGallus06162005.fasta] mitochondrial translational release factor 1, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Mitochondrial translational release factor 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 MITOCHONDRIAL TRANSLATIONAL RELEASE FACTOR 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=MTRF1 Peptide chain release factor 1, mitochondrial [human-ipi-250309-contam.fasta] mitochondrial translational release factor 1 precursor [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta] IPI:IPI00026157.2\|SWISS-PROT:O75570\|TREMBL:B3KNV2\|ENSEMBL:ENSP00000368790;ENSP00000368793\|REFSEQ:NP_004285\|H-INV:HIT000052679\|VEGA:OTTHUMP00000018315;OTTHUMP00000018316 Tax_Id=9606 Gene_Symbol=MTRF1 Peptide chain release factor 1, mitochondrial [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=MTRF1 Peptide chain release factor 1, mitochondrial precursor ENSG00000120662 IPI00167143 IPI00026157 IPI00642465 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=MTRF1 Peptide chain release factor 1, mitochondrial precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] peptide chain release factor 1, mitochondrial precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] O75570;Q5T6Y5;Q8IUQ6; RecName: Full=Peptide chain release factor 1, mitochondrial; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Peptide chain release factor 1, mitochondrial OS=Homo sapiens GN=MTRF1 [011711_HMR.fasta] GeneSymbol=MTRF1 Synonyms=MGC47721\|MRF1\|MTTRF1\|RF1 peptide chain release factor 1, mitochondrial precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Peptide chain release factor 1, mitochondrial GN=MTRF1 [Doctor+uniprot-HUMAN-120911.fasta] Mitochondrial translational release factor 1, isoform CRA_a OS=Homo sapiens GN=MTRF1 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
Organism:	Homo sapiens
Length:	445 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRHLCVWLF RHPSLNGYLQ CHIQLHSHQF RQIHLDTRLQ VFRQNRNCIL HLLSKNWSRR  60
   61 YCHQDTKMLW KHKALQKYME NLSKEYQTLE QCLQHIPVNE ENRRSLNRRH AELAPLAAIY 120
  121 QEIQETEQAI EELESMCKSL NKQDEKQLQE LALEERQTID QKINMLYNEL FQSLVPKEKY 180
  181 DKNDVILEVT AGRTTGGDIC QQFTREIFDM YQNYSCYKHW QFELLNYTPA DYGGLHHAAA 240
  241 RISGDGVYKH LKYEGGIHRV QRIPEVGLSS RMQRIHTGTM SVIVLPQPDE VDVKLDPKDL 300
  301 RIDTFRAKGA GGQHVNKTDS AVRLVHIPTG LVVECQQERS QIKNKEIAFR VLRARLYQQI 360
  361 IEKDKRQQQS ARKLQVGTRA QSERIRTYNF TQDRVSDHRI AYEVRDIKEF LCGGKGLDQL 420
  421 IQRLLQSADE EAIAELLDEH LKSAK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..445]	PSI-BLAST	118.0	Molecular basis for bacterial class 1 release factor methylation by PrmC

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.87

Protein Overview: MTRF1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: