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Protein Overview: ASL

General Information:
Name(s) found: ASL [HGNC (HUGO)]
Description(s) found:
Found 27 descriptions.
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  • argininosuccinate lyase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 464 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASESGKLWG GRFVGAVDPI MEKFNASIAY DRHLWEVDVQ GSKAYSRGLE KAGLLTKAEM  60
   61 DQILHGLDKV AEEWAQGTFK LNSNDEDIHT ANERRLKELI GATAGKLHTG RSRNDQVVTD 120
  121 LRLWMRQTCS TLSGLLWELI RTMVDRAEAE RDVLFPGYTH LQRAQPIRWS HWILSHAVAL 180
  181 TRDSERLLEV RKRINVLPLG SGAIAGNPLG VDRELLRAEL NFGAITLNSM DATSERDFVA 240
  241 EFLFWASLCM THLSRMAEDL ILYCTKEFSF VQLSDAYSTG SSLMPQKKNP DSLELIRSKA 300
  301 GRVFGRCAGL LMTLKGLPST YNKDLQEDKE AVFEVSDTMS AVLQVATGVI STLQIHQENM 360
  361 GQALSPDMLA TDLAYYLVRK GMPFRQAHEA SGKAVFMAET KGVALNQLSL QELQTISPLF 420
  421 SGDVICVWDY GHSVEQYGAL GGTARSSVDW QIRQVRALLQ AQQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..464] PSI-BLAST 136.0 Argininosuccinate lyase/delta-crystallin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • amidine-lyase activity
    		•  3.84281419858187 bayes_pls_golite062009
  • argininosuccinate lyase activity
    		•  3.58328346705456 bayes_pls_golite062009
  • catalytic activity
    		•  2.51282259572665 bayes_pls_golite062009
  • lyase activity
    		•  2.31268471569846 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  2.2046475419807 bayes_pls_golite062009
  • fumarate hydratase activity
    		•  1.8220456742683 bayes_pls_golite062009
  • histidine ammonia-lyase activity
    		•  0.948129236753279 bayes_pls_golite062009
  • binding
    		•  0.616567403608599 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.491229595527877 bayes_pls_golite062009
  • protein binding
    		•  0.110986062813054 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle