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Protein Overview: Pde11-PB, FBpp03...

General Information:
Name(s) found: FBpp0310380 [FlyBase]
Pde11-PB / FBpp0111456 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • type=protein; loc=2L:complement(18533335..18534459,18534518..18534601,18534661..18534877,18534940..18535128,18535185..18535294,18535361..18535528,18535586..18535672,18536814..18536990,18537166..18537687,18538030..18538185,18539523..18539673,18540629..18540768,18541185..18541620,18541857..18542003,18543262..18543715,18546525..18546717); ID=FBpp0310380; name=Pde11-PF; parent=FBgn0085370,FBtr0343830; dbxref=FlyBase:FBpp0310380,FlyBase_Annotation_IDs:CG34341-PF; MD5=7f033955a33716f551735984a792e538; length=1451; release=r5.56; species=Dmel; [FlyBase]
  • The gene Phosphodiesterase 11 is referred to in FlyBase by the symbol Dmel\Pde11 (CG34341, FBgn0085370). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:18532728..18571648. It has the cytological map location 36F6. There is experimental evidence that it has the molecular function</span>: 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-AMP phosphodiesterase activity. There is experimental evidence that it is involved in the biological process</span>: cAMP metabolic process; cGMP metabolic process. 12 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1451 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: cGMP metabolic process [IDA]
    signal transduction [IEA]
    cAMP metabolic process [IDA]
    Molecular Function: 3',5'-cyclic-GMP phosphodiesterase activity [IDA][ISS]
    3',5'-cyclic-AMP phosphodiesterase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQAASMCRF RGCRYKNKNK SSKQQQQQQQ QQQQQQQQHQ QQQQQTPSHS PQIQHHSEII  60
   61 PATTGLHLRS IEEPATTPLQ FQPTGRMNTE QGGTGYGGYG SSEHSLLIAT RHAGVPLPLA 120
  121 QHQPLPAHYQ PLNHSGAAPP SSSNGSSSSG GGVQTSATPQ QQQQYQVQQP YQYQYQHHYH 180
  181 HQANSPQHHR PYDPEHARME AWLDENQEFV QDYFIRKATR QTVDAWLVSH ATSAGNDVVS 240
  241 STSPTHANGQ TSSSRGGSGA TTPVRKISAH EFERGGLLKP IVNTIDGTPT FLSIGPPMDN 300
  301 GSVGGSCSNL QNVGGVVAGQ YQYNHQQHHH NHAHLHHSQH SHYQAGGAVG SSSLGSTGGA 360
  361 SGAGGAPSLG GSGGAGNGHQ YPYYHCHQRP QRLSRNELKQ LDEKELIFEL VKDICNELEV 420
  421 RTLCHKILQN VSILLNADRG SLFLVQGRCN GPDGLKKCLV SKLFDVCPRS TVEEMEQQDE 480
  481 VRVAWGTGIA GHVAESGEPV NIPDAYQDER FNCEIDSLTG YRTKALLCMP IKDSSGDVIG 540
  541 VAQVINKMNG ECFSEIDEKV FSSYLQFCGI GLRNAQLYEK SQLEIKRNQV LLDLARMIFE 600
  601 EQSTIEHMVF RILTHMQSLI QCQRVQILLV HEADKGSFSR VFDFEANDLS EEEATSRTSP 660
  661 YESRFPINIG ITGHVATTGE TVNVPNAYED DRFDASVDEN SCFKHRSILC MAIKNSLGQI 720
  721 IGVIQLINKF NELDFTKNDE NFVEAFAIFC GMGIHNTHMY EKAIVAMAKQ SVTLEVLSYH 780
  781 ASATMDEAHR LRRLRVPSAV HFRLHDFKFD DIHFEDDDTL KACLRMFLDL DFVERFHIDY 840
  841 EVLCRWLLSV KKNYRNVTYH NWRHAFNVAQ MMFAILTTTQ WWKIFGEIEC LALIIGCLCH 900
  901 DLDHRGTNNS FQIKASSPLA QLYSTSTMEH HHFDQCLMIL NSPGNQILAN LSSDDYCRVI 960
  961 RVLEDAILST DLAVYFKKRG PFLESVSQPT SYWVAEEPRA LLRAMSMTVC DLSAITKPWE1020
 1021 IEKRVADLVS SEFFEQGDME KQELNITPID IMNREKEDEL PMMQVNFIDS ICLPIYEAFA1080
 1081 TLSDKLEPLV EGVRDNRGHW IDLADVVKTK TSQDQEPEEE QQQQNVISNG DCKAMSDDDV1140
 1141 AASEAEVAVD SPSEKASVNG SNVANNSSNT NKKIAVASHP TSTQPSDDDN DVDADADDVD1200
 1201 EQAAEENGHD AEVDEASCRS NSTCSSSTAS SCLSTPPPTG EDDSTPVSPL KTLQAKLVAA1260
 1261 NLNALQRQTS NQAQTQKQRC KSCDHSRSGL QVRKTSSLRG AQELDLDSKT RNGTHAALCK1320
 1321 STPVINNHSH HHNHSHSHNH NHHHHHHHHS HHNHSQHGIG IGSASIGGSG LISLTTPLLA1380
 1381 MDSDRIPKIV GKIGNLDGLP FANGIGGPQN GHGLPFGSYQ HHHHHQHHHH LLARRHSETN1440
 1441 SNGATAMAVE K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle