Protein Overview: pan-PJ

General Information:
Name(s) found:	pan-PJ / FBpp0111569 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|172045736\|sp\|Q8IMA8.2\|PANG2_DROME RecName: Full=Protein pangolin, isoform J; AltName: Full=dTCF [NCBI NR] gi\|161076317\|ref\|NP_726528.2\| pangolin, isoform J [Drosophila melanogaster] [NCBI NR] gi\|157400020\|gb\|AAN06549.2\| pangolin, isoform J [Drosophila melanogaster] [NCBI NR] Protein pangolin, isoform J OS=Drosophila melanogaster GN=pan PE=1 SV=2 [Swiss-Prot] The gene pangolin is referred to in FlyBase by the symbol Dmel\pan (CG34403, FBgn0085432). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:89956..129430. It has the cytological map location 102A3-102A4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of Wnt receptor signaling pathway; spiracle morphogenesis, open tracheal system; embryonic pattern specification; regulation of hemocyte differentiation; imaginal disc-derived wing morphogenesis; positive regulation of transcription; salivary gland morphogenesis. 44 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: organ system; adult segment; late extended germ band embryo; thoracic segment; muscle founder cell; embryonic/larval tracheal system; peripheral nervous system; adult mesothoracic segment; spiracle; cuticle. It has 10 annotated transcripts and 10 annotated polypeptides. [FlyBase] type=protein; loc=4:join(111840..113899,115049..115241,115463..115628,120032..120101,128029..129118); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs: [fly-100309-contam.fasta] type=protein; loc=4:join(111840..113899,115049..115241,115463..115628,120032..120101,128029..129118); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs:CG34403-PJ,GB_protein:AAN06549,FlyBase_Annotation_IDs:CG32005-PA,REFSEQ:NP_726528,GB_protein:AAN06549; MD5=ada4e5be2480512479a16dd9ea41e08b; length=1192; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=4:join(111840..113899,115049..115241,115463..115628,120032..120101,128029..129118); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs:CG34403-PJ,GB_protein:AAN06549,FlyBase_Annotation_IDs:CG32005-PA,REFSEQ:NP_726528,GB_protein:AAN06549; MD5=ada4e5be2480512479a16dd9ea41e08b; length=1192; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=4:join(111840..113899,115049..115241,115463..115628,120032..120101,128029..129118); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs:CG34403-PJ,GB_protein:AAN06549,FlyBase_Annotation_IDs:CG32005-PA,REFSEQ:NP_726528,GB_protein:AAN06549,FlyMine:FBpp0111569,modMine:FBpp0111569; MD5=ada4e5be2480512479a16dd9ea41e08b; length=1192; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=4:join(91214..93273,94423..94615,94837..95002,99406..99475,107403..108492); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs:CG34403-PJ,GB_protein:AAN06549,FlyBase_Annotation_IDs:CG32005-PA,REFSEQ:NP_726528,GB_protein:AAN06549,FlyMine:FBpp0111569,modMine:FBpp0111569; MD5=ada4e5be2480512479a16dd9ea41e08b; length=1192; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=4:join(91214..93273,94423..94615,94837..95002,99406..99475,107403..108492); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs:CG34403-PJ,GB_protein:AAN06549,FlyBase_Annotation_IDs:CG32005-PA,REFSEQ:NP_726528,GB_protein:AAN06549,FlyMine:FBpp0111569,modMine:FBpp0111569; MD5=ada4e5be2480512479a16dd9ea41e08b; length=1192; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0111569 type=protein; loc=4:join(91214..93273,94423..94615,94837..95002,99406..99475,107403..108492); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs:CG34403-PJ,GB_protein:AAN06549,FlyBase_Annotation_IDs:CG32005-PA,REFSEQ:NP_726528,GB_protein:AAN06549,FlyMine:FBpp0111569,modMine:FBpp0111569; MD5=ada4e5be2480512479a16dd9ea41e08b; length=1192; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=4:join(91214..93273,94423..94615,94837..95002,99406..99475,107403..108492); ID=FBpp0111569; name=pan-PJ; parent=FBgn0085432,FBtr0112657; dbxref=GB_protein:AAN06549.1,FlyBase:FBpp0111569,FlyBase:FBpp0088230,FlyBase_Annotation_IDs:CG34403-PJ,GB_protein:AAN06549,FlyBase_Annotation_IDs:CG32005-PA,REFSEQ:NP_726528,GB_protein:AAN06549,UniProt/Swiss-Prot:Q8IMA8,FlyMine:FBpp0111569,modMine:FBpp0111569; MD5=ada4e5be2480512479a16dd9ea41e08b; length=1192; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1192 amino acids
Gene Ontology:
Cellular Component:	transcription factor complex [ISS]
Biological Process:	spiracle morphogenesis, open tracheal system [IMP] embryonic pattern specification [IMP] imaginal disc-derived wing morphogenesis [IMP] regulation of hemocyte differentiation [IMP] regulation of transcription, DNA-dependent [ISS] segment polarity determination [NAS] positive regulation of transcription [IMP] mesodermal cell fate determination [TAS] salivary gland morphogenesis [IMP] heart development [TAS] Wnt receptor signaling pathway [NAS][TAS] negative regulation of Wnt receptor signaling pathway [NAS] regulation of Wnt receptor signaling pathway [IMP]
Molecular Function:	DNA binding [IEA] specific transcriptional repressor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHCGTTNSE INLNSNELIS YQKKKSNEDL QKKHDKKCSI NLKTSQVPDG GFNNQYTQLT  60
   61 ANKIEQYNCN DLDKVCIVPS SRSDGMEASF SELLLSPNKL ISQPWQTAEE IENWQNDSFR 120
  121 QRNEMFSCIY TNSMLNQQPC SQQQLLATQL LYARLLRSQL AEREFHSNKF NMVHYSGSKK 180
  181 TMLREDELLS TPSSQDNNNN IKLIKDIENS ISCVDPPLFE FSNVHQRAEQ KNKQDDKNCY 240
  241 SPKLKSNKEA LDGYDLQHTC DFIREQKNIL IDIKKKLDNL SDSSGKFRKR LSVRQSHIEV 300
  301 NNGSNSALEE SVRRQLNGNR KSIENLLEEV KRLYNQWSSA ELYYVRSLQR LGLPSEEDGE 360
  361 YTSTPTHTIM ALAAIALSNE SILPQKTNAV HSKIPDVESE SDFFLTSAKP KTLVEIEDII 420
  421 LQLASSVNMH QSSSASTPHE SYSDSVKSDC EESNSAPTCI WHSTRQTFRH KKDVEPCSTA 480
  481 AEIILEYASL SSSSNIETSR LLTSASNLTD VTENYNVTTQ LPIVFNYNRE SSAESIVTDP 540
  541 LLVPEFSTAP STPSTGSNSG CSTGMVSGIF GLSQNRRKQR LARHIETLTT NSFKSNAIRG 600
  601 NVDNEITNQL KTSPSIRALP TENVSHLITK TLSSANASLT AQELSITNLF KERLCALQGN 660
  661 AGSMKTEIFP MIDAPYDLSI GSKTKHMNLE AKHTSNAQSN ESKETTNDKK KPHIKKPLNA 720
  721 FMLYMKEMRA KVVAECTLKE SAAINQILGR RWHELSREEQ SKYYEKARQE RQLHMELYPG 780
  781 WSARDNYGYV SKKKKRKKDR STTDSGGNNM KKCRARFGLD QQSQWCKPCR RKKKCIRYME 840
  841 ALNGNGPAED GSCFDEHGSQ LSDDDEDDYD DDKLGGSCGS ADETNKIEDE DSESLNQSMP 900
  901 SPGCLSGLSS LQSPSTTMSL ASPLNMNANS ATNVIFPASS NALLIVGADQ PTAQQRPTLV 960
  961 STSGSSSGST SSISTTPNTS STVSPVTCMT GPCLGSSQER AMMLGNRFSH LGMGLSPPVV1020
 1021 STSTSKSEPF FKPHPTVCNN PIFALPSIGN CSLNISSMPN TSRNPIGANP RDINNPLSIN1080
 1081 QLTKRREYKN VELIEASESK TIVAHAATSI IQHVAVNGYH ANHSLLNSNL GHLHHQLNNR1140
 1141 TENPNRSEQT MLSVSNHSVN SSECHKESDS QAIVSSNPPN AGSSDNGVIS VS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: pan-PJ

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: