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Protein Overview: XGPT_ECOLI

General Information:
Name(s) found: XGPT_ECOLI [Swiss-Prot]
Description(s) found:
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  • gi|71164800|sp|P0A9M5.1|XGPT_ECOLI RecName: Full=Xanthine phosphoribosyltransferase; AltName: Full=Xanthine-guanine phosphoribosyltransferase; Short=XGPRT [NCBI NR]
  • pir||RTECGX xanthine phosphoribosyltransferase (EC 2.4.2.22) - Escherichia coli (strain K-12) [NCBI NR]
  • gi|4902973|dbj|BAA77907.1| guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli W3110] [NCBI NR]
  • gi|41609|emb|CAA25041.1| unnamed protein product [Escherichia coli] [NCBI NR]
  • gi|41607|emb|CAA25040.1| xanthine-guanine phospho- ribosyl transferase [Escherichia coli] [NCBI NR]
  • gi|3891411|pdb|1A96|D Chain D, Xprtase From E. Coli With Bound Cprpp And Xanthine [NCBI NR]
  • gi|3891410|pdb|1A96|C Chain C, Xprtase From E. Coli With Bound Cprpp And Xanthine [NCBI NR]
  • gi|3891409|pdb|1A96|B Chain B, Xprtase From E. Coli With Bound Cprpp And Xanthine [NCBI NR]
  • gi|3891408|pdb|1A96|A Chain A, Xprtase From E. Coli With Bound Cprpp And Xanthine [NCBI NR]
  • gi|3891407|pdb|1A95|D Chain D, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [NCBI NR]
  • gi|3891406|pdb|1A95|C Chain C, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [NCBI NR]
  • gi|3891405|pdb|1A95|B Chain B, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [NCBI NR]
  • gi|3891404|pdb|1A95|A Chain A, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [NCBI NR]
  • pir||G85512 guanine-hypoxanthine phosphoribosyltransferase [imported] - Escherichia coli (strain O157:H7, substrain EDL933) [NCBI NR]
  • pir||A90662 guanine-hypoxanthine phosphoribosyltransferase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) [NCBI NR]
  • gi|224295|prf||1101279A transferase,Xan-guanine phosphoribosyl [NCBI NR]
  • gi|2194033|pdb|1NUL|B Chain B, Xprtase From E. Coli [NCBI NR]
  • gi|2194032|pdb|1NUL|A Chain A, Xprtase From E. Coli [NCBI NR]
  • gi|209745302|gb|ACI70958.1| guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli] [NCBI NR]
  • gi|209745300|gb|ACI70957.1| guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli] [NCBI NR]
  • gi|209745298|gb|ACI70956.1| guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli] [NCBI NR]
  • gi|209745296|gb|ACI70955.1| guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli] [NCBI NR]
  • gi|209745294|gb|ACI70954.1| guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli] [NCBI NR]
  • gi|1552806|gb|AAB08658.1| xanthine-guanine phosphoribosyltransferase [Escherichia coli] [NCBI NR]
  • gi|146262|gb|AAA23932.1| xanthine-guanine phosphoribosyl transferase [NCBI NR]
  • gi|146256|gb|AAA23928.1| xanthine-guanine phosphoribosyl transferase [Escherichia coli] [NCBI NR]
  • Xanthine phosphoribosyltransferase (EC 2.4.2.22) (Xanthine-guanine phosphoribosyltransferase) (XGPRT) - Escherichia coli [Swiss-Prot]
  • guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli K12]gi|15829519|ref|NP_308292.1| guanine-hypoxanthine phosphoribosyltransferase [Escherichia coli O157:H7]gi|30061855|ref|NP_836026.1| guanine-hypoxanthine phosphoribosyltransferase [Shige [nrdb_11152004_Chlamydomonas]
  • Xanthine phosphoribosyltransferase (Xanthine-guanine phosphoribosyltransferase) (XGPRT) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • Chain C, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [nr-271106-contam.fasta]
  • Chain A, Xprtase From E. Coli [nr-271106-contam.fasta]
  • Chain B, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [nr-271106-contam.fasta]
  • Chain C, Xprtase From E. Coli With Bound Cprpp And Xanthine [nr-271106-contam.fasta]
  • transferase,Xan-guanine phosphoribosyl [nr-271106-contam.fasta]
  • xanthine-guanine phosphoribosyl transferase [Escherichia coli] [nr-271106-contam.fasta]
  • Chain B, Xprtase From E. Coli [nr-271106-contam.fasta]
  • Chain A, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [nr-271106-contam.fasta]
  • unnamed protein product [Escherichia coli] [nr-271106-contam.fasta]
  • xanthine-guanine phosphoribosyl transferase [nr-271106-contam.fasta]
  • xanthine-guanine phosphoribosyltransferase [Escherichia coli] [nr-271106-contam.fasta]
  • xanthine-guanine phospho- ribosyl transferase [Escherichia coli] [nr-271106-contam.fasta]
  • Chain D, Xprtase From E. Coli Complexed With Mg:cprpp And Guanine [nr-271106-contam.fasta]
  • Chain A, Xprtase From E. Coli With Bound Cprpp And Xanthine [nr-271106-contam.fasta]
  • Chain D, Xprtase From E. Coli With Bound Cprpp And Xanthine [nr-271106-contam.fasta]
  • Chain B, Xprtase From E. Coli With Bound Cprpp And Xanthine [nr-271106-contam.fasta]
  • Xanthine phosphoribosyltransferase OS=Escherichia coli (strain K12) GN=gpt PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 152 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKYIVTWD MLQIHARKLA SRLMPSEQWK GIIAVSRGGL VPGALLAREL GIRHVDTVCI  60
   61 SSYDHDNQRE LKVLKRAEGD GEGFIVIDDL VDTGGTAVAI REMYPKAHFV TIFAKPAGRP 120
  121 LVDDYVVDIP QDTWIEQPWD MGVVFVPPIS GR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. XGPT_ECOLI gi|134105085, gi... gi|189095939, gi...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 30.522879 Xantine-guanine PRTase (XPRTase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • adenine phosphoribosyltransferase activity
    		•  4.07252508868782 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  3.91023158228049 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  3.89356447922614 bayes_pls_golite062009
  • transferase activity
    		•  2.73727660668741 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.53679639481311 bayes_pls_golite062009
  • catalytic activity
    		•  2.30431811394775 bayes_pls_golite062009
  • uracil phosphoribosyltransferase activity
    		•  2.20660111782431 bayes_pls_golite062009
  • amidophosphoribosyltransferase activity
    		•  1.51802880667162 bayes_pls_golite062009
  • purine binding
    		•  1.3774977535406 bayes_pls_golite062009
  • nucleobase binding
    		•  1.28671115202467 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  1.18255665419929 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.882962388159961 bayes_pls_golite062009
  • xanthine phosphoribosyltransferase activity
    		•  0.607713614998293 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.148898393751978 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle