YRC Public Data Repository - Protein Structure Prediction

Protein:	XGPT_ECOLI
Organism:	Escherichia coli
Length:	152 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XGPT_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|224354 - gi\|224354\|prf\|\|1102210A protein gpt	140.0	[0..1]	[152..1]
XGPT_DESAG - Xanthine phosphoribosyltransferase OS=Desulfovibrio alaskensis (strain G20) GN=gpt PE=3 SV=1	132.0	[0..7]	[152..13]
gi\|90579862, gi\|... - gi\|90579862\|ref\|ZP_01235670.1\| xanthine phosphoribosyltransferase [Vibrio angustum S14], gi\|90438747...	131.0	[0..1]	[152..1]
XGPT_MANSM - Xanthine phosphoribosyltransferase OS=Mannheimia succiniciproducens (strain MBEL55E) GN=gpt PE=3 SV=...	131.0	[0..1]	[152..1]
gi\|121549627, gi... - gi\|121586215\|ref\|ZP_01676006.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae 2740-80]... gi\|124114437, gi... - gi\|153216179\|ref\|ZP_01950318.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae 1587], g... gi\|153221338, gi... - gi\|153221338\|ref\|ZP_01952316.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae MAK 757]... gi\|153819510, gi... - gi\|153819510\|ref\|ZP_01972177.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae NCTC 845... gi\|229352120, gi... - gi\|229512155\|ref\|ZP_04401634.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae B33], gi... gi\|148876286, gi... - gi\|153828197\|ref\|ZP_01980864.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae 623-39],... gi\|197752536, gi... - gi\|254286051\|ref\|ZP_04961012.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae AM-19226... gi\|149739398, gi... - gi\|153826811\|ref\|ZP_01979478.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae MZO-2], ... gi\|116188817, gi... - gi\|75830050\|ref\|ZP_00759336.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-... XGPT_VIBC3 - Xanthine phosphoribosyltransferase OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Oga... gi\|229369809, gi... - gi\|229607154\|ref\|YP_002877802.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae MJ-1236... XGPT_VIBCH - Xanthine phosphoribosyltransferase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba ... gi\|75822602, gi\|... - gi\|75822602\|ref\|ZP_00752197.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-... gi\|229528722, gi... - gi\|229528722\|ref\|ZP_04418112.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae 12129(1)... XGPT_VIBCH - Xanthine phosphoribosyltransferase OS=Vibrio cholerae GN=gpt PE=3 SV=1 gi\|116219409, gi... - gi\|75818765\|ref\|ZP_00748890.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-... gi\|229524279, gi... - gi\|229524279\|ref\|ZP_04413684.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae bv. albe... gi\|121630821, gi... - gi\|75815787\|ref\|ZP_00746280.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-... gi\|229522222, gi... - gi\|229522222\|ref\|ZP_04411639.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae TM 11079... gi\|229519290, gi... - gi\|229519290\|ref\|ZP_04408733.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae RC9], gi... gi\|229349099, gi... - gi\|229513918\|ref\|ZP_04403380.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae TMA 21],... gi\|229507650, gi... - gi\|229507650\|ref\|ZP_04397155.1\| xanthine-guanine phosphoribosyltransferase [Vibrio cholerae BX 33028... XGPT_VIBCM - Xanthine phosphoribosyltransferase OS=Vibrio cholerae serotype O1 (strain M66-2) GN=gpt PE=3 SV=1	131.0	[0..1]	[152..1]
gi\|89073177, gi\|... - gi\|89073177\|ref\|ZP_01159716.1\| xanthine phosphoribosyltransferase [Photobacterium sp. SKA34], gi\|890...	131.0	[0..1]	[152..1]
XGPT_SALTI - Xanthine phosphoribosyltransferase OS=Salmonella typhi GN=gpt PE=3 SV=1 gi\|204323856, gi... - gi\|204927191\|ref\|ZP_03218393.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enter... XGPT_SALTI - Xanthine phosphoribosyltransferase OS=Salmonella typhi GN=gpt PE=3 SV=1 XGPT_SALG2 - Xanthine phosphoribosyltransferase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=gpt PE=3... XGPT_SALEP - Xanthine phosphoribosyltransferase OS=Salmonella enteritidis PT4 (strain P125109) GN=gpt PE=3 SV=1 gi\|213161391 - gi\|213161391\|ref\|ZP_03347101.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... gi\|16759312 - gi\|16759312\|ref\|NP_454929.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subsp. ... gi\|197242926, gi... - gi\|197264671\|ref\|ZP_03164745.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enter... XGPT_SALPK - Xanthine phosphoribosyltransferase OS=Salmonella paratyphi A (strain AKU_12601) GN=gpt PE=3 SV=1 XGPT_SALTY - Xanthine phosphoribosyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) G... XGPT_SALDC - Xanthine phosphoribosyltransferase OS=Salmonella dublin (strain CT_02021853) GN=gpt PE=3 SV=1 gi\|29142915, gi\|... - gi\|29142915\|ref\|NP_806257.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subsp. ... gi\|200389461, gi... - gi\|200389461\|ref\|ZP_03216072.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enter... XGPT_SALHS - Xanthine phosphoribosyltransferase OS=Salmonella heidelberg (strain SL476) GN=gpt PE=3 SV=1 gi\|194458952, gi... - gi\|194472588\|ref\|ZP_03078572.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enter... XGPT_SALSV - Xanthine phosphoribosyltransferase OS=Salmonella schwarzengrund (strain CVM19633) GN=gpt PE=3 SV=1 gi\|238913293 - gi\|238913293\|ref\|ZP_04657130.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... XGPT_SALA4 - Xanthine phosphoribosyltransferase OS=Salmonella agona (strain SL483) GN=gpt PE=3 SV=1 gi\|168261268, gi... - gi\|205349890\|gb\|EDZ36521.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|195631763, gi... - gi\|195631763\|gb\|EDX50283.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enterica ... XGPT_SALCH - Xanthine phosphoribosyltransferase OS=Salmonella choleraesuis (strain SC-B67) GN=gpt PE=3 SV=1 gi\|168819092, gi... - gi\|205344021\|gb\|EDZ30785.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enterica ... XGPT_SALPA - Xanthine phosphoribosyltransferase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=gpt PE=3... XGPT_SALNS - Xanthine phosphoribosyltransferase OS=Salmonella newport (strain SL254) GN=gpt PE=3 SV=1 XGPT_SALPC - Xanthine phosphoribosyltransferase OS=Salmonella paratyphi C (strain RKS4594) GN=gpt PE=3 SV=1 gi\|213649628 - gi\|213649628\|ref\|ZP_03379681.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... gi\|213852527 - gi\|213852527\|ref\|ZP_03382059.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... gi\|213979993 - gi\|213979993\|ref\|ZP_03407252.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... gi\|214001714 - gi\|214001714\|ref\|ZP_03412449.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... gi\|213418462 - gi\|213418462\|ref\|ZP_03351528.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... XGPT_SALCH - Xanthine phosphoribosyltransferase OS=Salmonella choleraesuis GN=gpt PE=3 SV=1 gi\|213425144 - gi\|213425144\|ref\|ZP_03357894.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... XGPT_SALPA - Xanthine phosphoribosyltransferase OS=Salmonella paratyphi A GN=gpt PE=3 SV=1 gi\|213583863 - gi\|213583863\|ref\|ZP_03365689.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... gi\|213619323 - gi\|213619323\|ref\|ZP_03373149.1\| xanthine-guanine phosphoribosyltransferase [Salmonella enterica subs... XGPT_SALTY - Xanthine phosphoribosyltransferase OS=Salmonella typhimurium GN=gpt PE=3 SV=1 lcl\|NC_016856.1_... - [gene=gpt] [protein=xanthine-guanine phosphoribosyltransferase] [protein_id=YP_005235991.1] [locatio... XGPT_SALCH - Xanthine phosphoribosyltransferase OS=Salmonella choleraesuis GN=gpt PE=3 SV=1 XGPT_SALTY - Xanthine phosphoribosyltransferase OS=Salmonella typhimurium GN=gpt PE=3 SV=1 gi\|205328624, gi... - gi\|205328624\|gb\|EDZ15388.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enterica ... XGPT_SALPB - Xanthine phosphoribosyltransferase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=gpt PE... gi\|168232272, gi... - gi\|205333367\|gb\|EDZ20131.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enterica ... XGPT_SALAR - Xanthine phosphoribosyltransferase OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980... gi\|197288582, gi... - gi\|197288582\|gb\|EDY27959.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|205339803, gi... - gi\|205339803\|gb\|EDZ26567.1\| xanthine phosphoribosyltransferase [Salmonella enterica subsp. enterica ... XGPT_SALPB - Xanthine phosphoribosyltransferase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=gpt PE...	130.0	[0..1]	[152..1]
gi\|77957136 - gi\|77957136\|ref\|ZP_00821200.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-... gi\|77962909, gi\|... - gi\|77962909\|ref\|ZP_00826724.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-...	129.0	[0..1]	[152..1]
XGPT_ACTSZ - Xanthine phosphoribosyltransferase OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) GN=gpt ...	129.0	[0..1]	[152..1]
XGPT_ECOL5 - Xanthine phosphoribosyltransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=gpt PE=3 SV... XGPT_ECOL6 - Xanthine phosphoribosyltransferase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN... XGPT_ECOL6 - Xanthine phosphoribosyltransferase OS=Escherichia coli O6 GN=gpt PE=3 SV=1 XGPT_ECO27 - Xanthine phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=gpt PE=3 ... sp\|B7UJC6\|XGPT_ECO27 - Xanthine phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=gpt PE=3 ... gi\|191171457, gi... - gi\|75241690\|ref\|ZP_00725527.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-... gi\|227884746, gi... - gi\|227884746\|ref\|ZP_04002551.1\| xanthine-guanine phosphoribosyltransferase [Escherichia coli 83972],... XGPT_ECO81 - Xanthine phosphoribosyltransferase OS=Escherichia coli O81 (strain ED1a) GN=gpt PE=3 SV=1	129.0	[0..1]	[152..1]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKYIVTWD MLQIHARKLA SRLMPSEQWK GIIAVSRGGL VPGALLAREL GIRHVDTVCI  60
   61 SSYDHDNQRE LKVLKRAEGD GEGFIVIDDL VDTGGTAVAI REMYPKAHFV TIFAKPAGRP 120
  121 LVDDYVVDIP QDTWIEQPWD MGVVFVPPIS GR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.522879
Match:	1a95A
Description:	Xantine-guanine PRTase (XPRTase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	4.07252508868782	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	3.89356447922614	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	2.20660111782431	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.51802880667162	bayes_pls_golite062009
purine binding	1.3774977535406	bayes_pls_golite062009
nucleobase binding	1.28671115202467	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.18255665419929	bayes_pls_golite062009
diphosphotransferase activity	0.882962388159961	bayes_pls_golite062009
xanthine phosphoribosyltransferase activity	0.607713614998293	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: