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Protein Overview: NPRL2

General Information:
Name(s) found: NPRL2 [HGNC (HUGO)]
Description(s) found:
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  • gi|50592992|ref|NP_006536.3| tumor suppressor candidate 4 [Homo sapiens] [NCBI NR]
  • gi|47117604|sp|Q8WTW4.2|TUSC4_HUMAN RecName: Full=Tumor suppressor candidate 4; AltName: Full=NPR2-like; AltName: Full=Gene 21 protein; Short=G21 protein [NCBI NR]
  • gi|3688795|gb|AAC62535.1| candidate tumor suppressor gene 21 protein isoform I [Homo sapiens] [NCBI NR]
  • gi|34785137|gb|AAH56861.1| Tumor suppressor candidate 4 [Homo sapiens] [NCBI NR]
  • gi|2340095|gb|AAB67310.1| similar to nitrogen permease regulator; similar to P39923 (PID:g730170), match to AA233630 (NID:g1856833) and AA399402 (NID:g2053147) [Homo sapiens] [NCBI NR]
  • gi|158257824|dbj|BAF84885.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119585511|gb|EAW65107.1| tumor suppressor candidate 4, isoform CRA_b [Homo sapiens] [NCBI NR]
  • tumor suppressor candidate 4 [HGNC (HUGO)]
  • nitrogen permease regulator-like 2 (S. cerevisiae) [HGNC (HUGO)]
  • Tumor suppressor candidate 4 OS=Homo sapiens GN=TUSC4 PE=1 SV=2 [Swiss-Prot]
  • (Q8WTW4) Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21 protein) [Swiss-Prot]
  • Nitrogen permease regulator 2-like protein OS=Homo sapiens GN=NPRL2 PE=1 SV=2 [Swiss-Prot]
  • tumor suppressor candidate 4; 2810446G01Rik; homologous to yeast nitrogen permease (candidate tumor suppressor) [071204_hmrz_cont.fasta]
  • tumor suppressor candidate 4 [Homo sapiens]gi|34785137|gb|AAH56861.1| Tumor suppressor candidate 4 [Homo sapiens]gi|47117604|sp|Q8WTW4|TUS4_HUMAN Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21 protein)gi|3688795|gb|AAC62535.1| candidat [nrdb_11152004_Chlamydomonas]
  • Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21 protein) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Tumor suppressor candidate 4 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_006545) homologous to yeast nitrogen permease (candidate tumor suppressor) [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • tumor suppressor candidate 4 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • tumor suppressor candidate 4, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tumor suppressor candidate 4 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • similar to nitrogen permease regulator; similar to P39923 (PID:g730170), match to AA233630 (NID:g1856833) and AA399402 (NID:g2053147) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • candidate tumor suppressor gene 21 protein isoform I [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Tumor suppressor candidate 4 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF TUMOR SUPPRESSOR CANDIDATE 4 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=TUSC4 Isoform 1 of Tumor suppressor candidate 4 [human-ipi-250309-contam.fasta]
  • IPI:IPI00410108.3|SWISS-PROT:Q8WTW4-1|TREMBL:A8K831|ENSEMBL:ENSP00000232501|REFSEQ:NP_006536|H-INV:HIT000259586|VEGA:OTTHUMP00000171303;OTTHUMP00000210836 Tax_Id=9606 Gene_Symbol=TUSC4 Isoform 1 of Tumor suppressor candidate 4 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=TUSC4 Isoform 1 of Tumor suppressor candidate 4 ENSG00000114388 IPI00410108 IPI00795672 IPI00792162 IPI00791550 IPI00383701 IPI00790161 IPI00789494 IPI00796017 IPI00790526 [drosphohumanreversed.fasta]
  • Q8WTW4;A8K831;Q6FGS2;Q9Y249;Q9Y497; RecName: Full=Tumor suppressor candidate 4; AltName: Full=NPR2-like protein; AltName: Full=Gene 21 protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Nitrogen permease regulator 2-like protein OS=Homo sapiens GN=NPRL2 [011711_HMR.fasta]
  • IPI:IPI00410108.3|SWISS-PROT:Q8WTW4-1|ENSEMBL:ENSP00000232501|REFSEQ:NP_006536|H-INV:HIT000259586|VEGA:OTTHUMP00000171303;OTTHUMP00000210836 Tax_Id=9606 Gene_Symbol=TUSC4 Isoform 1 of Tumor suppressor candidate 4 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=NPRL2 Synonyms=NPR2|NPR2L|TUSC4 nitrogen permease regulator 2-like protein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00410108.3|SWISS-PROT:Q8WTW4-1|ENSEMBL:ENSP00000232501|REFSEQ:NP_006536|H-INV:HIT000259586|VEGA:OTTHUMP00000210836 Tax_Id=9606 Gene_Symbol=NPRL2 Isoform 1 of Nitrogen permease regulator 2-like protein [ipi.HUMAN.20110912.fasta]
  • Nitrogen permease regulator 2-like protein GN=NPRL2 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=NPRL2 Isoform 1 of Nitrogen permease regulator 2-like protein [human-ipi-270911-contam-BSA.fasta]
  • GATOR complex protein NPRL2 OS=Homo sapiens GN=NPRL2 PE=1 SV=2 [human-uniprot-05July2017-contam-hTTBK1.fasta]
    • Organism: Homo sapiens
    Length: 380 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSGCRIECI FFSEFHPTLG PKITYQVPED FISRELFDTV QVYIITKPEL QNKLITVTAM  60
   61 EKKLIGCPVC IEHKKYSRNA LLFNLGFVCD AQAKTCALEP IVKKLAGYLT TLELESSFVS 120
  121 MEESKQKLVP IMTILLEELN ASGRCTLPID ESNTIHLKVI EQRPDPPVAQ EYDVPVFTKD 180
  181 KEDFFNSQWD LTTQQILPYI DGFRHIQKIS AEADVELNLV RIAIQNLLYY GVVTLVSILQ 240
  241 YSNVYCPTPK VQDLVDDKSL QEACLSYVTK QGHKRASLRD VFQLYCSLSP GTTVRDLIGR 300
  301 HPQQLQHVDE RKLIQFGLMK NLIRRLQKYP VRVTREEQSH PARLYTGCHS YDEICCKTGM 360
  361 SYHELDERLE NDPNIIICWK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..115] MSA 2.027997 View MSA. No confident structure predictions are available.
    2 View Details [116..316] MSA 2.029927 View MSA. No confident structure predictions are available.
    3 View Details [317..380] MSA 1.020979 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle