Protein Overview: THAA_DANRE

General Information:
Name(s) found:	THAA_DANRE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|66911171\|gb\|AAH96778.1\| Thyroid hormone receptor alpha a [Danio rerio] [NCBI NR] gi\|6094469\|sp\|Q98867.1\|THAA_DANRE RecName: Full=Thyroid hormone receptor alpha-A; Short=zTRalpha-A; AltName: Full=Thyroid hormone receptor alpha-1; Short=TRalpha-1; AltName: Full=Nuclear receptor subfamily 1 group A member 1-A [NCBI NR] gi\|24308535\|ref\|NP_571471.1\| thyroid hormone receptor alpha a [Danio rerio] [NCBI NR] gi\|22204200\|emb\|CAD43414.1\| thyroid hormone receptor alpha [Danio rerio] [NCBI NR] gi\|182889166\|gb\|AAI64729.1\| Thraa protein [Danio rerio] [NCBI NR] gi\|1314773\|gb\|AAA99811.1\| thyroid hormone receptor alpha 1 [Danio rerio] [NCBI NR] Thyroid hormone receptor alpha OS=Danio rerio GN=thra PE=2 SV=1 [Swiss-Prot] Thyroid hormone receptor alpha-A OS=Danio rerio GN=thraa PE=1 SV=1 [Swiss-Prot] Thyroid hormone receptor alpha 1 - Danio rerio (Zebrafish) (Brachydanio rerio) [Swiss-Prot] Thyroid hormone receptor alpha 1 - Brachydanio rerio (Zebrafish) (Danio rerio) [Swiss-Prot] thyroid hormone receptor alpha; thyroid hormone receptor alpha 1 [071204_hmrz_cont.fasta] thyroid hormone receptor alpha [Danio rerio]gi\|1314773\|gb\|AAA99811.1\| thyroid hormone receptor alpha 1 [Danio rerio]gi\|6094469\|sp\|Q98867\|THA1_BRARE Thyroid hormone receptor alpha 1 [nrdb_11152004_Chlamydomonas] thyroid hormone receptor alpha [Danio rerio] [nr-271106-contam.fasta] Thyroid hormone receptor alpha 1 [nr-271106-contam.fasta] Thyroid hormone receptor alpha [Danio rerio] [nr-271106-contam.fasta] thyroid hormone receptor alpha 1 [Danio rerio] [nr-271106-contam.fasta] thyroid hormone receptor alpha-A [Danio rerio] [NCBI-RefSeq_D_rerio_na_08-30-2010_reversed.fasta] RecName: Full=Thyroid hormone receptor alpha-A; Short=zTRalpha-A; AltName: Full=Nuclear receptor subfamily 1 group A member 1-A; AltName: Full=Thyroid hormone receptor alpha-1; Short=TRalpha-1 [NCBI_RefSeq_D_rerio_20120531_05-31-2012_reversed.fasta]
Organism:	Danio rerio
Length:	427 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][IEA]
Biological Process:	negative regulation of transcription from RNA polymerase II promoter [IMP] transcription [IEA] multicellular organismal development [IEA] regulation of transcription, DNA-dependent [IDA][IEA] regulation of transcription [IEA] response to hormone stimulus [IDA] positive regulation of transcription from RNA polymerase II promoter [IMP]
Molecular Function:	thyroid hormone receptor activity [IDA][IEA] DNA binding [IEA] transcription factor activity [IEA] zinc ion binding [IEA] protein binding [IPI] ligand-dependent nuclear receptor activity [IEA] metal ion binding [IEA] steroid hormone receptor activity [IEA] sequence-specific DNA binding [IEA] transcription activator activity [IDA] transcription repressor activity [IDA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENTEQEHNL PEGDETQWPN GVKRKRKNSQ CSMNSTSDKS ISVPGYVPSY LEKDEPCVVC  60
   61 GDKATGYHYR CITCEGCKGF FRRTIQKNLH PSYSCKYDSC CIIDKITRNQ CQLCRFRKCI 120
  121 SVGMAMDLVL DDSKRVAKRR LIEENREKRK KEEIVKTLHN RPEPTVSEWE LIRMVTEAHR 180
  181 HTNAQGPHWK QKRKFLPEDI GQSPAPTSDN DKVDLEAFSE FTKIITPAIT RVVDFAKKLP 240
  241 MFSELPCEDQ IILLKGCCME IMSLRAAVRY DPESETLTLS GEMAVSREQL KNGGLGVVSD 300
  301 AIFDLGKSLS QFNLDDSEVA LLQAVLLMSS DRSGLTCVEK IEKCQEMYLL AFEHYINHRK 360
  361 HNISHFWPKL LMKVTNLRMI GACHASRFLH MKVECPTELF PPLFLEVFED QEGSTGVAAQ 420
  421 EDGSCLR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: THAA_DANRE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: