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Protein Overview: SMAD5_DANRE

General Information:
Name(s) found: SMAD5_DANRE [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Mothers against decapentaplegic homolog 5 OS=Danio rerio GN=smad5 PE=2 SV=1 [Swiss-Prot]
    • Organism: Danio rerio
    Length: 464 amino acids

    Gene Ontology:
    Cellular Component: transcription factor complex [IEA]
    nucleus [IEA]
    cytoplasm [IEA]
    intracellular [IEA]
    Biological Process: transcription [IEA]
    dorsal convergence [IMP]
    multicellular organismal development [IEA]
    embryonic pattern specification [IMP]
    transforming growth factor beta receptor signaling pathway [IEA]
    regulation of transcription, DNA-dependent [IEA][NAS]
    blood vessel morphogenesis [IGI]
    embryonic heart tube morphogenesis [IMP]
    regulation of transcription [IEA]
    otic placode formation [IEP]
    heart jogging [IMP]
    determination of left/right symmetry [IMP]
    dorsal/ventral pattern formation [IGI][IMP]
    determination of ventral identity [IDA][IGI][IMP]
    determination of dorsal/ventral asymmetry [IGI]
    BMP signaling pathway [IGI][IMP]
    heart looping [IMP]
    Molecular Function: transcription factor activity [IEA][NAS]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSMSSLFSF TSPAVKRLLG WKQGDEEEKW AEKAVDALVK KLKKKKGAME DLEKALSSPG  60
   61 QPSKCVTIPR SLDGRLQVSH RKGLPHVIYC RVWRWPDLQS HHELKPLEVC EYPFGSKQKE 120
  121 VCINPYHYKR VESPVLPPVL VPRHSEFNPQ HSLLVQFRNL SHNEPHMPLN ATFPESFQQH 180
  181 SGGSSFPISP NSPYPPSPAS SGTYPNSPAS SGPSSPFQLP ADTPPPAYMP PDEQMGQDGS 240
  241 QSMETGSSLA PQNMPRGDVQ PVEYQEPSHW CSIVYYELNN RVGEAYHASS TSVLVDGFTD 300
  301 PSNNKNRFCL GLLSNVNRNS TIENTRRHIG KGVHLYYVGG EVYAECLSDT SIFVQSRNCN 360
  361 YHHGFHPTTV CKIPSGCSLK IFNNQEFAQL LAQSVNHGFE AVYELTKMCT IRMSFVKGWG 420
  421 AEYHRQDVTS TPCWIEVHLH GPLQWLDKVL TQMGSPLNPI SSVS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.60

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle