Protein Overview: ELAC2

General Information:
Name(s) found:	ELAC2 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|41017788\|sp\|Q9BQ52.2\|RNZ2_HUMAN RecName: Full=Zinc phosphodiesterase ELAC protein 2; AltName: Full=Ribonuclease Z 2; Short=RNase Z 2; AltName: Full=tRNase Z 2; AltName: Full=tRNA 3 endonuclease 2; AltName: Full=ElaC homolog protein 2; AltName: Full=Her [NCBI NR] gi\|145553959\|ref\|NP_060597.4\| elaC homolog 2 [Homo sapiens] [NCBI NR] gi\|119610368\|gb\|EAW89962.1\| elaC homolog 2 (E. coli), isoform CRA_b [Homo sapiens] [NCBI NR] gi\|10880933\|gb\|AAG24441.1\|AF304370_1 putative prostate cancer susceptibility protein HPC2/ELAC2 [Homo sapiens] [NCBI NR] elaC homolog 2 (E. coli) [HGNC (HUGO)] Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens GN=ELAC2 PE=1 SV=2 [Swiss-Prot] Zinc phosphodiesterase ELAC protein 2 (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2) (Heredity prostate cancer protein 2)gi\|10880933\|gb\|AAG24441.1\| putative prostate cancer susceptibility protein HPC2/ELAC2 [Homo sapiens] [nrdb_11152004_Chlamydomonas] Zinc phosphodiesterase ELAC protein 2 (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2) (Heredity prostate cancer protein 2) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform 1 of Zinc phosphodiesterase ELAC protein 2 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] putative prostate cancer susceptibility protein HPC2/ELAC2 [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta] elaC homolog 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] elaC homolog 2 (E. coli), isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 1 of Zinc phosphodiesterase ELAC protein 2 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 SPLICE ISOFORM 1 OF ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=ELAC2 Isoform 1 of Zinc phosphodiesterase ELAC protein 2 [human-ipi-250309-contam.fasta] elaC homolog 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta] IPI:IPI00396627.1\|SWISS-PROT:Q9BQ52-1\|TREMBL:B4DPL9;B4DT15\|ENSEMBL:ENSP00000337445\|REFSEQ:NP_060597\|H-INV:HIT000076727\|VEGA:OTTHUMP00000064669;OTTHUMP00000183214 Tax_Id=9606 Gene_Symbol=ELAC2 Isoform 1 of Zinc phosphodiesterase ELAC protein 2 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=ELAC2 Isoform 1 of Zinc phosphodiesterase ELAC protein 2 ENSG00000006744 IPI00396627 IPI00789842 IPI00398822 IPI00798145 IPI00398823 [drosphohumanreversed.fasta] Q9BQ52;Q6IA94;Q9HAS8;Q9HAS9;Q9NVT1; RecName: Full=Zinc phosphodiesterase ELAC protein 2; AltName: Full=Ribonuclease Z 2; AltName: Full=tRNase Z 2; AltName: Full=tRNA 3 endonuclease 2; AltName: Full=ElaC homolog protein 2; AltName: Full=Heredity prostate cancer protein 2; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 1 of Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens GN=ELAC2 [011711_HMR.fasta] IPI:IPI00396627.1\|SWISS-PROT:Q9BQ52-1\|TREMBL:B4DT15\|ENSEMBL:ENSP00000337445\|REFSEQ:NP_060597\|H-INV:HIT000076727\|VEGA:OTTHUMP00000064669;OTTHUMP00000183214 Tax_Id=9606 Gene_Symbol=ELAC2 Isoform 1 of Zinc phosphodiesterase ELAC protein 2 [ipi.HUMAN.fasta.20100406] GeneSymbol=ELAC2 Synonyms=ELC2\|FLJ10530\|FLJ36693\|FLJ42848\|HPC2 zinc phosphodiesterase ELAC protein 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00396627.1\|SWISS-PROT:Q9BQ52-1\|TREMBL:B4DT15;E9PGJ0\|ENSEMBL:ENSP00000337445\|REFSEQ:NP_060597\|H-INV:HIT000076727\|VEGA:OTTHUMP00000064669 Tax_Id=9606 Gene_Symbol=ELAC2 Isoform 1 of Zinc phosphodiesterase ELAC protein 2 [ipi.HUMAN.20110912.fasta] Zinc phosphodiesterase ELAC protein 2 GN=ELAC2 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	826 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWALCSLLRS AAGRTMSQGR TISQAPARRE RPRKDPLRHL RTREKRGPSG CSGGPNTVYL  60
   61 QVVAAGSRDS GAALYVFSEF NRYLFNCGEG VQRLMQEHKL KVARLDNIFL TRMHWSNVGG 120
  121 LSGMILTLKE TGLPKCVLSG PPQLEKYLEA IKIFSGPLKG IELAVRPHSA PEYEDETMTV 180
  181 YQIPIHSEQR RGKHQPWQSP ERPLSRLSPE RSSDSESNEN EPHLPHGVSQ RRGVRDSSLV 240
  241 VAFICKLHLK RGNFLVLKAK EMGLPVGTAA IAPIIAAVKD GKSITHEGRE ILAEELCTPP 300
  301 DPGAAFVVVE CPDESFIQPI CENATFQRYQ GKADAPVALV VHMAPASVLV DSRYQQWMER 360
  361 FGPDTQHLVL NENCASVHNL RSHKIQTQLN LIHPDIFPLL TSFRCKKEGP TLSVPMVQGE 420
  421 CLLKYQLRPR REWQRDAIIT CNPEEFIVEA LQLPNFQQSV QEYRRSAQDG PAPAEKRSQY 480
  481 PEIIFLGTGS AIPMKIRNVS ATLVNISPDT SLLLDCGEGT FGQLCRHYGD QVDRVLGTLA 540
  541 AVFVSHLHAD HHTGLPSILL QRERALASLG KPLHPLLVVA PNQLKAWLQQ YHNQCQEVLH 600
  601 HISMIPAKCL QEGAEISSPA VERLISSLLR TCDLEEFQTC LVRHCKHAFG CALVHTSGWK 660
  661 VVYSGDTMPC EALVRMGKDA TLLIHEATLE DGLEEEAVEK THSTTSQAIS VGMRMNAEFI 720
  721 MLNHFSQRYA KVPLFSPNFS EKVGVAFDHM KVCFGDFPTM PKLIPPLKAL FAGDIEEMEE 780
  781 RREKRELRQV RAALLSRELA GGLEDGEPQQ KRAHTEEPQA KKVRAQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..464]	PSI-BLAST	52.0	Crystal structure of RNase Z
2	View Details	[465..826]	PSI-BLAST	38.522879	No description for 2i7tA was found.

Protein Overview: ELAC2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: