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Protein Overview: PFLB_ECOLI

General Information:
Name(s) found: PFLB_ECOLI [Swiss-Prot]
Description(s) found:
Found 22 descriptions.
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  • (P09373) Formate acetyltransferase 1 (EC 2.3.1.54) (Pyruvate formate-lyase 1) [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 759 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SELNEKLATA WEGFTKGDWQ NEVNVRDFIQ KNYTPYEGDE SFLAGATEAT TTLWDKVMEG  60
   61 VKLENRTHAP VDFDTAVAST ITSHDAGYIN KQLEKIVGLQ TEAPLKRALI PFGGIKMIEG 120
  121 SCKAYNRELD PMIKKIFTEY RKTHNQGVFD VYTPDILRCR KSGVLTGLPD AYGRGRIIGD 180
  181 YRRVALYGID YLMKDKLAQF TSLQADLENG VNLEQTIRLR EEIAEQHRAL GQMKEMAAKY 240
  241 GYDISGPATN AQEAIQWTYF GYLAAVKSQN GAAMSFGRTS TFLDVYIERD LKAGKITEQE 300
  301 AQEMVDHLVM KLRMVRFLRT PEYDELFSGD PIWATESIGG MGLDGRTLVT KNSFRFLNTL 360
  361 YTMGPSPEPN MTILWSEKLP LNFKKFAAKV SIDTSSLQYE NDDLMRPDFN NDDYAIACCV 420
  421 SPMIVGKQMQ FFGARANLAK TMLYAINGGV DEKLKMQVGP KSEPIKGDVL NYDEVMERMD 480
  481 HFMDWLAKQY ITALNIIHYM HDKYSYEASL MALHDRDVIR TMACGIAGLS VAADSLSAIK 540
  541 YAKVKPIRDE DGLAIDFEIE GEYPQFGNND PRVDDLAVDL VERFMKKIQK LHTYRDAIPT 600
  601 QSVLTITSNV VYGKKTGNTP DGRRAGAPFG PGANPMHGRD QKGAVASLTS VAKLPFAYAK 660
  661 DGISYTFSIV PNALGKDDEV RKTNLAGLMD GYFHHEASIE GGQHLNVNVM NREMLLDAME 720
  721 NPEKYPQLTI RVSGYAVRFN SLTKEQQQDV ITRTFTQSM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..759] PSI-BLAST 1000.0 Pyruvate formate-lyase, PFL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.95058695475279 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
    		•  1.72563679072631 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH or CH2 groups
    		•  1.43559439297918 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.42705638794743 bayes_pls_golite062009
  • ribonucleoside-diphosphate reductase activity
    		•  1.37298861502572 bayes_pls_golite062009
  • C-acyltransferase activity
    		•  0.0923196663496405 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle