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Protein Overview: pen-2-PA, FBpp03...

General Information:
Name(s) found: FBpp0309291 [FlyBase]
pen-2-PA / FBpp0088783 [FlyBase]
Description(s) found:
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  • gi|50403787|sp|Q86BE9.3|PEN2_DROME RecName: Full=Gamma-secretase subunit pen-2; AltName: Full=Presenilin enhancer protein 2 [NCBI NR]
  • gi|45552066|ref|NP_788401.2| presenilin enhancer [Drosophila melanogaster] [NCBI NR]
  • gi|45445482|gb|AAO41356.2| presenilin enhancer [Drosophila melanogaster] [NCBI NR]
  • gi|157816738|gb|ABV82362.1| IP20177p [Drosophila melanogaster] [NCBI NR]
  • gi|157816658|gb|ABV82322.1| IP19977p [Drosophila melanogaster] [NCBI NR]
  • Gamma-secretase subunit pen-2 OS=Drosophila melanogaster GN=pen-2 PE=1 SV=3 [Swiss-Prot]
  • type=protein; loc=2R:join(14165126..14165186,14165256..14165360,14165435..14165574); ID=FBpp0309291; name=pen-2-PB; parent=FBgn0053198,FBtr0340331; dbxref=FlyBase:FBpp0309291,FlyBase_Annotation_IDs:CG33198-PB; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r5.56; species=Dmel; [FlyBase]
  • The gene presenilin enhancer is referred to in FlyBase by the symbol Dmel\pen-2 (CG33198, FBgn0053198). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14165031..14165658. It has the cytological map location 55C2. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. The biological processes in which it is involved are not known. 16 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • (AAO41356) CG33198-PA [DrosMelano7227.FASTAC.txt]
  • CG33198-PA [Drosophila melanogaster]gi|45552066|ref|NP_788401.2| CG33198-PA [Drosophila melanogaster]gi|50403787|sp|Q86BE9|PEN2_DROME Gamma-secretase subunit pen-2 (Presenilin enhancer protein 2) [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(14165126..14165186,14165256..14165360,14165435..14165574); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,RE [fly-100309-contam.fasta]
  • CG33198-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Gamma-secretase subunit pen-2 (Presenilin enhancer protein 2) [nr-271106-contam.fasta]
  • presenilin enhancer CG33198-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(14165126..14165186,14165256..14165360,14165435..14165574); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,REFSEQ:NP_788401,GB_protein:AAO41356; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(14165126..14165186,14165256..14165360,14165435..14165574); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,REFSEQ:NP_788401,GB_protein:AAO41356; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2R:join(14165126..14165186,14165256..14165360,14165435..14165574); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,REFSEQ:NP_788401,GB_protein:AAO41356,FlyMine:FBpp0088783,modMine:FBpp0088783; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,REFSEQ:NP_788401,GB_protein:AAO41356,FlyMine:FBpp0088783,modMine:FBpp0088783; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0309291; name=pen-2-PB; parent=FBgn0053198,FBtr0340331; dbxref=FlyBase:FBpp0309291,FlyBase_Annotation_IDs:CG33198-PB,GB_protein:AHN56361,REFSEQ:NP_001286566; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,REFSEQ:NP_788401,GB_protein:AAO41356,FlyMine:FBpp0088783,modMine:FBpp0088783; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0309291; name=pen-2-PB; parent=FBgn0053198,FBtr0340331; dbxref=FlyBase:FBpp0309291,FlyBase_Annotation_IDs:CG33198-PB,GB_protein:AHN56361,REFSEQ:NP_001286566; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q86BE9, Presenilin enhancer, isoform B OS=Drosophila melanogaster GN=pen-2 PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0088783 type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,REFSEQ:NP_788401,GB_protein:AAO41356,FlyMine:FBpp0088783,modMine:FBpp0088783; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0309291 type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0309291; name=pen-2-PB; parent=FBgn0053198,FBtr0340331; dbxref=FlyBase:FBpp0309291,FlyBase_Annotation_IDs:CG33198-PB,GB_protein:AHN56361,REFSEQ:NP_001286566; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0088783; name=pen-2-PA; parent=FBgn0053198,FBtr0089842; dbxref=GB_protein:AAO41356.1,FlyBase:FBpp0088783,FlyBase_Annotation_IDs:CG33198-PA,GB_protein:AAO41356.2,REFSEQ:NP_788401,GB_protein:AAO41356,UniProt/Swiss-Prot:Q86BE9,FlyMine:FBpp0088783,modMine:FBpp0088783; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2R:join(18277621..18277681,18277751..18277855,18277930..18278069); ID=FBpp0309291; name=pen-2-PB; parent=FBgn0053198,FBtr0340331; dbxref=FlyBase:FBpp0309291,FlyBase_Annotation_IDs:CG33198-PB,GB_protein:AHN56361,REFSEQ:NP_001286566,UniProt/Swiss-Prot:Q86BE9; MD5=5d255956c363c58b1c18815c91ea1a82; length=101; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 101 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NAS]
    Biological Process: NONE FOUND
    Molecular Function: endopeptidase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDISKAPNPR KLELCRKYFF AGFAFLPFVW AINVCWFFTE AFHKPPFSEQ SQIKRYVIYS  60
   61 AVGTLFWLIV LTAWIIIFQT NRTAWGATAD YMSFIIPLGS A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A Confident ab initio structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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