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Protein Overview: PEN2_DANRE

General Information:
Name(s) found: PEN2_DANRE [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Gamma-secretase subunit PEN-2 OS=Danio rerio GN=psenen PE=3 SV=1 [Swiss-Prot]
    • Organism: Danio rerio
    Length: 101 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA][NAS]
    Biological Process: Notch signaling pathway [IEA]
    negative regulation of apoptosis [IMP]
    negative regulation of neuron apoptosis [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLERIPNEE KLSLCRRYYL GGFAFLPFLW LVNILWFFKE AFLKPAYTEQ PQIKSYVKKS  60
   61 ALGLLLWVAV LTTWITVFQH FRAQWGEVGD YLSFTIPLGT A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.44862313972188 bayes_pls_golite062009
  • protein binding
    		•  1.69141488569616 bayes_pls_golite062009
  • cadherin binding
    		•  0.655643448891613 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.474766150716424 bayes_pls_golite062009
  • catalytic activity
    		•  0.20779478258019 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle