Protein Overview: Myo61F-PA

General Information:
Name(s) found:	Myo61F-PA / FBpp0072568 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45551497\|ref\|NP_728594.2\| myosin 61F, isoform A [Drosophila melanogaster] [NCBI NR] gi\|45445731\|gb\|AAF47477.3\| myosin 61F, isoform A [Drosophila melanogaster] [NCBI NR] gi\|41019509\|sp\|Q23979.3\|MY61F_DROME RecName: Full=Myosin-IB; Short=MIB; AltName: Full=Brush border myosin IB; Short=BBMIB [NCBI NR] Myosin-IB OS=Drosophila melanogaster GN=Myo61F PE=1 SV=3 [Swiss-Prot] (Q23979) Myosin IB (MIB) (Brush border myosin IB) (BBMIB) [Swiss-Prot] The gene Myosin 61F is referred to in FlyBase by the symbol Dmel\Myo61F (CG9155, FBgn0010246). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1318482..1329623. It has the cytological map location 61F6. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. There is experimental evidence that it is involved in the biological process</span>: determination of left/right symmetry; defense response to bacterium; microvillus organization; mesoderm development. 11 alleles are reported. The phenotypes of these alleles are annotated with: embryonic hindgut; enterocyte; embryonic midgut; microvillus; brush border; larval midgut. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] (AAF47477) CG9155-PA [DrosMelano7227.FASTAC.txt] CG9155-PA, isoform A [Drosophila melanogaster]gi\|45551497\|ref\|NP_728594.2\| CG9155-PA [Drosophila melanogaster]gi\|41019509\|sp\|Q23979\|MY1B_DROME Myosin IB (MIB) (Brush border myosin IB) (BBMIB) [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF4 [fly-100309-contam.fasta] CG9155-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Myosin 61F CG9155-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Myosin IB (MIB) (Brush border myosin IB) (BBMIB) [nr-271106-contam.fasta] type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF47477.3,FlyBase:FBpp0072568,FlyBase_Annotation_IDs:CG9155-PA,REFSEQ:NP_728594,GB_protein:AAF47477; MD5=eed588ba9b564ce02b4efa97de2e787d; length=1035; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF47477.3,FlyBase:FBpp0072568,FlyBase_Annotation_IDs:CG9155-PA,REFSEQ:NP_728594,GB_protein:AAF47477; MD5=eed588ba9b564ce02b4efa97de2e787d; length=1035; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF47477.3,FlyBase:FBpp0072568,FlyBase_Annotation_IDs:CG9155-PA,REFSEQ:NP_728594,GB_protein:AAF47477,FlyMine:FBpp0072568,modMine:FBpp0072568; MD5=eed588ba9b564ce02b4efa97de2e787d; length=1035; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF47477.3,FlyBase:FBpp0072568,FlyBase_Annotation_IDs:CG9155-PA,REFSEQ:NP_728594,GB_protein:AAF47477,FlyMine:FBpp0072568,modMine:FBpp0072568; MD5=eed588ba9b564ce02b4efa97de2e787d; length=1035; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF47477.3,FlyBase:FBpp0072568,FlyBase_Annotation_IDs:CG9155-PA,REFSEQ:NP_728594,GB_protein:AAF47477,FlyMine:FBpp0072568,modMine:FBpp0072568; MD5=eed588ba9b564ce02b4efa97de2e787d; length=1035; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0072568 type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF47477.3,FlyBase:FBpp0072568,FlyBase_Annotation_IDs:CG9155-PA,REFSEQ:NP_728594,GB_protein:AAF47477,FlyMine:FBpp0072568,modMine:FBpp0072568; MD5=eed588ba9b564ce02b4efa97de2e787d; length=1035; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(1325253..1325260,1325995..1326139,1326201..1326316,1326373..1326835,1326898..1329161,1329224..1329320,1329401..1329415); ID=FBpp0072568; name=Myo61F-PA; parent=FBgn0010246,FBtr0072675; dbxref=GB_protein:AAF47477.2,GB_protein:AAF47477.3,FlyBase:FBpp0072568,FlyBase_Annotation_IDs:CG9155-PA,REFSEQ:NP_728594,GB_protein:AAF47477,UniProt/Swiss-Prot:Q23979,FlyMine:FBpp0072568,modMine:FBpp0072568; MD5=eed588ba9b564ce02b4efa97de2e787d; length=1035; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1035 amino acids
Gene Ontology:
Cellular Component:	myosin complex [IEA][ISS] brush border [IDA] cytoplasm [NAS]
Biological Process:	microvillus organization [IMP] mesoderm development [IEP] defense response to bacterium [IMP] determination of left/right symmetry [IMP]
Molecular Function:	ATP binding [IEA] actin binding [NAS] ATPase activity, coupled [ISS] motor activity [IEA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASFNSQLKM ETGLHERDRA GVQDFVLLEN YQSEEAFIGN LKKRFQEDLI YTYIGQVLIS  60
   61 VNPYKQLPIY TDDHVKAYRN KHFYEMPPHI FAVTDNAFRS LIEENRGQCV LISGESGSGK 120
  121 TEASKKVLQF IAACSGNQTT VEGVKDKLLK SNPVLEAFGN AKTNRNDNSS RFGKYMDIQF 180
  181 DFKGAPIGGN ILNYLLEKSR VVAQMGGERN FHIFYQLLAG ADEALLQELR LERALDTYSY 240
  241 LTDGLNGTVT RINDADSFKQ VQQALTVIDF TKEEQREIFG IVASILHLGN VGFTEVEGNA 300
  301 KVNSRDLVVT AARLLGVNAS ELEAALTHRT IDARGDVVTS PLNQELAIYA RDALAKAVYD 360
  361 RLFSWLVQRL NISLQAKETR ASRNNVMGIL DIYGFEIFQK NSFEQFCINF CNEKLQQLFI 420
  421 ELTLKSEQDE YRREGIEWIP VEYFDNKVIC NLIEEKHKGI ISILDEECLR PGEPTDKTFL 480
  481 EKLTQKLAQH HHYVCHEKAP AHIKKIMLRD EFRLVHYAGE VTYSVNGFLD KNNDLLFRDL 540
  541 KETLSKAGNG IVRNCFPEKE LRSLKRPETA ITQFRASLNN LMDILMCKEP SYIRCIKPND 600
  601 LQTANVFNDE LVLHQVKYLG LMENLRVRRA GFAYRRTYEL FLERYKSLSK STWPNYKGPG 660
  661 GPKAGVQQLV KDLGWDEEKY RVGETKLFIR WPRTLFDTED AYQEKKHEIA AIIQAHWKGL 720
  721 MQRRKYLKLR AQVIIMQSYC RRKLAQQAAK KRREAADKIR AFIKGFITRN DAPNGFNEEF 780
  781 IANAKRMWLL RLAKELPTKV LDKSWPHAPG HCEEASGILH RLHRLHLARI YRLKLTPQQK 840
  841 RQFELKVLAE KVFKGKKNNY ASSVSTWFQE DRIPKEHIQR VNDFVASTFG SEQLKYQSFC 900
  901 TKFDRHGYKS RDRFILLSNK AIYVLDGKTY KQKHRLPLDK IDFTLTNHND DLMVIRIPLD 960
  961 LKKDKGDLIL IIPRIIEFST YIIDTVGTAS IVSIVDRNSL EHNVVKGKGG VIDIQTGAEP1020
 1021 GVVRDKGHLV IIGTQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: Myo61F-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: