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Protein Overview: mec-4

General Information:
Name(s) found: mec-4 / CE39109 [WormBase]
Description(s) found:
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  • WBGene00003168 locus:mec-4 Degenerin mec-4 status:Partially_confirmed UniProt:P24612 protein_id:CCD68838.1 [WormBase]
  • gi|86565107|ref|NP_510712.2| MEChanosensory abnormality family member (mec-4) [Caenorhabditis elegans] [NCBI NR]
  • gi|74356167|gb|AAB00580.3| Mechanosensory abnormality protein 4 [Caenorhabditis elegans] [NCBI NR]
  • gi|2507405|sp|P24612.3|MEC4_CAEEL RecName: Full=Degenerin mec-4; AltName: Full=Mechanosensory abnormality protein 4 [NCBI NR]
  • gi|1297371|gb|AAC47265.1| MEC-4 [NCBI NR]
  • Degenerin mec-4 OS=Caenorhabditis elegans GN=mec-4 PE=1 SV=3 [Swiss-Prot]
  • MEC-4gi|2507405|sp|P24612|MEC4_CAEEL Degenerin mec-4 (Mechanosensory abnormality protein 4) [nrdb_11152004_Chlamydomonas]
  • CE39109 WBGene00003168 locus:mec-4 status:Partially_confirmed [wormpep150.fasta]
  • [wormpep130-phg-ecoli-orf-rand.fasta]
  • 39109 WBGene00003168 locus:mec-4 status:Partially_confirmed [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE39109 WBGene00003168 locus:mec-4 status:Partially_confirmed UniProt:P24612 protein_id:AAB00580.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE39109 WBGene00003168 locus:mec-4 status:Partially_confirmed UniProt:P24612 protein_id:AAB00580.3| [wormORF-contam.fasta]
  • CE39109 WBGene00003168 locus:mec-4 status:Partially_confirmed SW:P24612 protein_id:AAB00580.3 [wormpep160-contam.fasta]
  • MEChanosensory abnormality family member (mec-4) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • MEC-4 [nr-271106-contam.fasta]
  • Mechanosensory abnormality protein 4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Degenerin mec-4 (Mechanosensory abnormality protein 4) [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE39109 WBGene00003168 locus:mec-4 status:Partially_confirmed UniProt:P24612 protein_id:CCD68838.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE39109 WBGene00003168 locus:mec-4 status:Partially_confirmed UniProt:P24612 protein_id:CCD68838.1 Degenerin mec-4 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 768 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IDALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: mechanosensory behavior [IMPLink to PubMed article]
    sodium ion transport [IEALink to PubMed article]
    ion transport [IEALink to PubMed article]
    response to mechanical stimulus [IMPLink to PubMed article]
    Molecular Function: ion channel activity [IEALink to PubMed article]
    sodium channel activity [IEALink to PubMed article]
    amiloride-sensitive sodium channel activity [IDALink to PubMed article][IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWMQNLKNY QHLRDPSEYM SQVYGDPLAY LQETTKFVTE REYYEDFGYG ECFNSTESEV  60
   61 QCELITGEFD PKLLPYDKRL AWHFKEFCYK TSAHGIPMIG EAPNVYYRAV WVVLFLGCMI 120
  121 MLYLNAQSVL DKYNRNEKIV DIQLKFDTAP FPAITLCNLN PYKASLATSV DLVKRTLSAF 180
  181 DGAMGKAGGN KDHEEEREVV TEPPTTPAPT TKPARRRGKR DLSGAFFEPG FARCLCGSQG 240
  241 SSEQEDKDEE KEEELLETTT KKVFNINDAD EEWDGMEEYD NEHYENYDVE ATTGMNMMEE 300
  301 CQSERTKFDE PTGFDDRCIC AFDRSTHDAW PCFLNGTWET TECDTCNEHA FCTKDNKTAK 360
  361 GHRSPCICAP SRFCVAYNGK TPPIEIWTYL QGGTPTEDPN FLEAMGFQGM TDEVAIVTKA 420
  421 KENIMFAMAT LSMQDRERLS TTKRELVHKC SFNGKACDIE ADFLTHIDPA FGSCFTFNHN 480
  481 RTVNLTSIRA GPMYGLRMLV YVNASDYMPT TEATGVRLTI HDKEDFPFPD TFGYSAPTGY 540
  541 VSSFGLRLRK MSRLPAPYGD CVPDGKTSDY IYSNYEYSVE GCYRSCFQQL VLKECRCGDP 600
  601 RFPVPENARH CDAADPIARK CLDARMNDLG GLHGSFRCRC QQPCRQSIYS VTYSPAKWPS 660
  661 LSLQIQLGSC NGTAVECNKH YKENGAMVEV FYEQLNFEML TESEAYGFVN LLADFGGQLG 720
  721 LWCGISFLTC CEFVFLFLET AYMSAEHNYS LYKKKKAEKA KKIASGSF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] deduced N/A No confident structure predictions are available.
    2 View Details [70..357] FFAS03 3.61 No description for 2qtsA was found.
    3 View Details [358..768] PSI-BLAST 81.045757 No description for 2qtsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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