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Protein Overview: efa-6

General Information:
Name(s) found: efa-6 / CE40826 [WormBase]
Description(s) found:
Found 12 descriptions.
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  • WBGene00013223 locus:efa-6 status:Confirmed UniProt:G5EBY7 protein_id:CAM82814.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 765 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: regulation of ARF protein signal transduction [IEALink to PubMed article]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVASSGAE EALATIDGAP RRNVKKSEAF VMSGDVLISL NRNVSSTYAK LLGDQLPPGT  60
   61 TVASSIHPHQ LSRATASAGV SFPSMNRNGA AAQKLSRLPV STSQIERRGS LARKTSEESS 120
  121 PTAIRMLKTA PIERMESTDV EESEEETVMM TTDEKENQKK PNENDDEVMV VDEEQFIDGP 180
  181 SRSPVYDDVD DDLNGSLDAK DMSNNSHQQS FRSPENYSEK DTPSKHSVVT IDGSGVSNHY 240
  241 DQDGMFSHVY YSTQDTTPKH GSPSLRKQIF ESRTTPNTAA SNSSASASPS LHATSESRGA 300
  301 TGGVSLRSAE SSNLNQTAVP STSTNSVGGE REAAQIARNL YELKNCTSTQ VADRLNEQNE 360
  361 FSFLILVKYL ELFQFSTTRI DAALREFLSR VELRGESSAR ERLLRVFSAR YLECNPAIFD 420
  421 SLDEVHTLTC ALLLLNSDLH GPNMGKKMTA RDFITNIAHT GCTFKREMLK TLFQSIKDNA 480
  481 ISLQNSAKNS TANGSVASTS RRQPQQIYEV DPDSVVEYYS GFLMRKYVRE TDGGKTPFGR 540
  541 RSWRMVYARL RGLVLYFDTD EHPKATSRYA SLENAVSLHH ALAEPAPDYK KKSFVFRVRI 600
  601 AHGGEILFQT SNQKELQEWC EKINFVAAAF SSPTLPLPVT SKPETAPMPR LPRIPCLAPI 660
  661 TKQLSTHEAR VAELNEMIEI VSQSVSPNQP QQLITDRWVL LSFEKRRYST YINVLRRSLE 720
  721 ARKASSATTM NIMMTPTRRQ QQNQKPVVSE DRLSYTDAVN GAAAH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..228] MSA 6.229988 View MSA. No confident structure predictions are available.
    2 View Details [229..283] deduced N/A No confident structure predictions are available.
    3 View Details [284..377] PSI-BLAST 69.221849 CYTOHESIN-1/B2-1 SEC7 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
    4 View Details [378..650] PSI-BLAST 25.154902 Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
    5 View Details [651..765] MSA 1.13599 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle