YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: efa-6
Organism: Caenorhabditis elegans
Length: 765 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for efa-6.

Description E-value Query
Range
Subject
Range
PSD2_MOUSE - PH and SEC7 domain-containing protein 2 OS=Mus musculus GN=Psd2 PE=1 SV=1
451.0 [0..43] [764..15]
gi|109078900 - gi|109078900|ref|XP_001085258.1| PREDICTED: similar to pleckstrin and Sec7 domain containing 2 [Maca...
448.0 [0..62] [763..35]
gi|109507115, gi... - ref|XP_226019.2| similar to hypothetical protein DKFZp761B0514 [Rattus norvegicus], gi|157817620|ref...
447.0 [0..52] [764..26]
gi|114619018 - gi|114619018|ref|XP_001147765.1| PREDICTED: similar to guanine nucleotide exchange factor for ADP ri...
444.0 [0..79] [759..259]
efa-6 - Sec7 domain status:Confirmed UniProt:Q9XWG7 protein_id:CAA21701.1
444.0 [0..1] [765..1]

Back

Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVASSGAE EALATIDGAP RRNVKKSEAF VMSGDVLISL NRNVSSTYAK LLGDQLPPGT  60
   61 TVASSIHPHQ LSRATASAGV SFPSMNRNGA AAQKLSRLPV STSQIERRGS LARKTSEESS 120
  121 PTAIRMLKTA PIERMESTDV EESEEETVMM TTDEKENQKK PNENDDEVMV VDEEQFIDGP 180
  181 SRSPVYDDVD DDLNGSLDAK DMSNNSHQQS FRSPENYSEK DTPSKHSV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [229-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTIDGSGVSN HYDQDGMFSH VYYSTQDTTP KHGSPSLRKQ IFESRTTPNT AASNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [284-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASASPSLHA TSESRGATGG VSLRSAESSN LNQTAVPSTS TNSVGGEREA AQIARNLYEL  60
   61 KNCTSTQVAD RLNEQNEFSF LILVKYLELF QFST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.221849
Match: 1bc9A
Description: CYTOHESIN-1/B2-1 SEC7 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [378-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRIDAALREF LSRVELRGES SARERLLRVF SARYLECNPA IFDSLDEVHT LTCALLLLNS  60
   61 DLHGPNMGKK MTARDFITNI AHTGCTFKRE MLKTLFQSIK DNAISLQNSA KNSTANGSVA 120
  121 STSRRQPQQI YEVDPDSVVE YYSGFLMRKY VRETDGGKTP FGRRSWRMVY ARLRGLVLYF 180
  181 DTDEHPKATS RYASLENAVS LHHALAEPAP DYKKKSFVFR VRIAHGGEIL FQTSNQKELQ 240
  241 EWCEKINFVA AAFSSPTLPL PVTSKPETAP MPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.154902
Match: 1xdvA
Description: Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [651-765]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPRIPCLAPI TKQLSTHEAR VAELNEMIEI VSQSVSPNQP QQLITDRWVL LSFEKRRYST  60
   61 YINVLRRSLE ARKASSATTM NIMMTPTRRQ QQNQKPVVSE DRLSYTDAVN GAAAH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle