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Protein Overview: IHFA_ECOLI

General Information:
Name(s) found: IHFA_ECOLI [Swiss-Prot]
Description(s) found:
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  • pir||IQECAA integration host factor himA alpha chain - Escherichia coli (strain K-12) [NCBI NR]
  • gi|68304092|gb|AAY89704.1| IhfA [Escherichia coli] [NCBI NR]
  • gi|67466106|sp|P0A6X7.1|IHFA_ECOLI RecName: Full=Integration host factor subunit alpha; Short=IHF-alpha [NCBI NR]
  • gi|43072|emb|CAA23566.1| unnamed protein product [Escherichia coli] [NCBI NR]
  • gi|34811469|pdb|1OWG|A Chain A, Crystal Structure Of Wt Ihf Complexed With An Altered H' Site (T44a) [NCBI NR]
  • gi|34811464|pdb|1OWF|A Chain A, Crystal Structure Of A Mutant Ihf (Betae44a) Complexed With The Native H' Site [NCBI NR]
  • gi|34811459|pdb|1OUZ|A Chain A, Crystal Structure Of A Mutant Ihf (Betae44a) Complexed With A Variant H' Site (T44a) [NCBI NR]
  • pir||G85779 integration host factor himA alpha chain - Escherichia coli (strain O157:H7, substrain EDL933) [NCBI NR]
  • pir||C90931 integration host factor IHF alpha subunit [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) [NCBI NR]
  • gi|209768906|gb|ACI82765.1| integration host factor IHF alpha subunit [Escherichia coli] [NCBI NR]
  • gi|209768904|gb|ACI82764.1| integration host factor IHF alpha subunit [Escherichia coli] [NCBI NR]
  • gi|209768902|gb|ACI82763.1| integration host factor IHF alpha subunit [Escherichia coli] [NCBI NR]
  • gi|209768900|gb|ACI82762.1| integration host factor IHF alpha subunit [Escherichia coli] [NCBI NR]
  • gi|209768898|gb|ACI82761.1| integration host factor IHF alpha subunit [Escherichia coli] [NCBI NR]
  • gi|1942275|pdb|1IHF|A Chain A, Integration Host FactorDNA COMPLEX [NCBI NR]
  • dbj|BAA15492.1| Integration host factor a-subunit (IHF-alpha). [Escherichia coli] [NCBI NR]
  • gi|1742792|dbj|BAA15480.1| integration host factor (IHF), DNA-binding protein, alpha subunit [Escherichia coli W3110] [NCBI NR]
  • gi|146347|gb|AAA51471.1| integration host factor alpha subunit [NCBI NR]
  • gi|119389941|pdb|2HT0|A Chain A, Ihf Bound To Doubly Nicked Dna [NCBI NR]
  • Integration host factor subunit alpha (IHF-alpha) - Escherichia coli [Swiss-Prot]
  • integration host factor (IHF), alpha subunit, DNA-bending protein, DNA replication; integration host factor (IHF), alpha subunit; site specific recombination [Escherichia coli K12]gi|15831673|ref|NP_310446.1| IHF; integration host factor alpha subunit [E [nrdb_11152004_Chlamydomonas]
  • Integration host factor subunit alpha (IHF-alpha) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • unnamed protein product [Escherichia coli] [nr-271106-contam.fasta]
  • integration host factor alpha subunit [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of A Mutant Ihf (Betae44a) Complexed With The Native H' Site [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of A Mutant Ihf (Betae44a) Complexed With A Variant H' Site (T44a) [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of Wt Ihf Complexed With An Altered H' Site (T44a) [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of An Ihf-Dna Complex: A Protein-Induced Dna U-Turn [nr-271106-contam.fasta]
  • Integration host factor subunit alpha OS=Escherichia coli (strain K12) GN=ihfA PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 99 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTKAEMSE YLFDKLGLSK RDAKELVELF FEEIRRALEN GEQVKLSGFG NFDLRDKNQR  60
   61 PGRNPKTGED IPITARRVVT FRPGQKLKSR VENASPKDE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. IHFA_ECOLI gi|134105085, gi... gi|189095939, gi...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] PSI-BLAST 29.522879 Integration host factor alpha subunit (IHFA)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA binding
    		•  5.25387001942839 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.15205953864352 bayes_pls_golite062009
  • binding
    		•  3.99545980559645 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.74311685689448 bayes_pls_golite062009
  • transcription activator activity
    		•  0.38454381783388 bayes_pls_golite062009
  • protein binding
    		•  0.262917207132993 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.176747764275359 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle