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Protein Overview: HIS6_CLOAB

General Information:
Name(s) found: HIS6_CLOAB [Swiss-Prot]
Description(s) found:
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  • pir||B97016 imidazoleglycerol-phosphate synthase [imported] - Clostridium acetobutylicum [NCBI NR]
  • gi|20454986|sp|Q97KH8.1|HIS6_CLOAB RecName: Full=Imidazole glycerol phosphate synthase subunit hisF; AltName: Full=IGP synthase cyclase subunit; AltName: Full=IGP synthase subunit hisF; AltName: Full=ImGP synthase subunit hisF; Short=IGPS subunit hisF [NCBI NR]
  • Imidazole glycerol phosphate synthase subunit HisF OS=Clostridium acetobutylicum GN=hisF PE=3 SV=1 [Swiss-Prot]
  • Imidazoleglycerol-phosphate synthase [Clostridium acetobutylicum ATCC 824]gi|15023843|gb|AAK78917.1| Imidazoleglycerol-phosphate synthase [Clostridium acetobutylicum ATCC 824]gi|25292238|pir||B97016 imidazoleglycerol-phosphate synthase [imported] - Clos [nrdb_11152004_Chlamydomonas]
  • Imidazole glycerol phosphate synthase subunit hisF (IGP synthase cyclase subunit) (IGP synthase subunit hisF) (ImGP synthase subunit hisF) (IGPS subunit hisF) [nr-271106-contam.fasta]
  • Imidazole glycerol phosphate synthase subunit HisF OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) GN=hisF PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Clostridium acetobutylicum
    Length: 253 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTKRIIPCL DVDMGRVVKG VNFVNLKDVG DPVEIADFYN REGADEIVFL DISATNEGRN  60
   61 TMIDVVRRTA EKVFIPLTVG GGIRDVDDFK NILRAGADKI SINSAAIRNP ELINEAAKKF 120
  121 GSQCVVVAVD ARRNIETGGF NVFINGGRVD TSLDAIEWVK KCESLGAGEI LLTSMDADGT 180
  181 KNGYDVELTG AVCDAVRIPV IASGGCGRLE DFDEIFKKTS ADAALVASLF HYKEYTVGEV 240
  241 KNYLRENSIQ VRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..253] PSI-BLAST 45.221849 Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • imidazoleglycerol-phosphate synthase activity
    		•  8.63799159510181 bayes_pls_golite062009
  • catalytic activity
    		•  2.44231061702877 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  1.13340776845419 bayes_pls_golite062009
  • indole-3-glycerol-phosphate synthase activity
    		•  0.549444136526559 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  0.426391242491024 bayes_pls_golite062009
  • lyase activity
    		•  0.258652421339738 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle