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Protein Overview: HIS4_RALSO

General Information:
Name(s) found: HIS4_RALSO [Swiss-Prot]
Description(s) found:
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  • gi|20454962|sp|Q8XV84.1|HIS4_RALSO RecName: Full=1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; AltName: Full=Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [NCBI NR]
  • gi|17429970|emb|CAD16654.1| probable phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase protein [Ralstonia solanacearum GMI1000] [NCBI NR]
  • 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase OS=Ralstonia solanacearum GN=hisA PE=3 SV=1 [Swiss-Prot]
  • PROBABLE PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE PROTEIN [Ralstonia solanacearum GMI1000]gi|17429970|emb|CAD16654.1| PROBABLE PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE PROTEIN [Ralstonia solan [nrdb_11152004_Chlamydomonas]
  • 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase) [nr-271106-contam.fasta]
  • 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase OS=Ralstonia solanacearum (strain GMI1000) GN=hisA PE=3 SV=1 [uniprot-Thibodeau_genera.fasta]
    • Organism: Ralstonia solanacearum
    Length: 247 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLIPAIDLK DGQCVRLKQG DMDQATVFSE DPAAMARHWV DQGARRLHLV DLNGAFVGKP  60
   61 RNEAAIKAII AEVGSEIPVQ LGGGIRDLNT IERWLDDGLS YVIIGTAAVK NPGFLQDACT 120
  121 AFGGHIIVGL DARDGKVATD GWSKLTGHEV VDLARKYEDY GVESIIYTDI GRDGMLQGIN 180
  181 IDATVKLAQS VSIPVIASGG LSSLKDIDHL CAVESEGVEG VICGRAIYSG DLNFREAQDH 240
  241 ADKLGAA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..247] PSI-BLAST 43.0 Crystal structure of the bifunctional protein Pria

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • imidazoleglycerol-phosphate synthase activity
    		•  8.63799159510181 bayes_pls_golite062009
  • catalytic activity
    		•  2.44231061702877 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  1.13340776845419 bayes_pls_golite062009
  • indole-3-glycerol-phosphate synthase activity
    		•  0.549444136526559 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  0.426391242491024 bayes_pls_golite062009
  • lyase activity
    		•  0.258652421339738 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle