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Protein Overview: gcy-37

General Information:
Name(s) found: gcy-37 / CE37494 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00001557 locus:gcy-37 Soluble guanylate cyclase gcy-37 status:Confirmed UniProt:Q6DNF3 protein_id:CCD68037.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 708 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cGMP biosynthetic process [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    cyclic nucleotide biosynthetic process [IEALink to PubMed article]
    Molecular Function: phosphorus-oxygen lyase activity [IEALink to PubMed article]
    guanylate cyclase activity [IEALink to PubMed article]
    heme binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGWTHVCVS ALILRKYGPE VLEEILRKAG YQEDIKFDIQ CYYDDTETMR IFRVAATVLG  60
   61 LSVDDMWEMY GEFLITHACE TGWQKMLFCM ANNLQEFLDN LNSMHYFIDQ IAFKSEMKGP 120
  121 TFQCEPFGES GLKLHYFSFR QGLFPIVKGL VRKTARTLFE MDVKVCMLER NQERRKSGMV 180
  181 EHVIFSVEPD DNHRKGKRLF HKFRNTKTTE NAPSFTLSST ILVGLRDFKN IFPYHVCFNK 240
  241 QMIIEHIGIY LLREYGLENK KTLKVSDLMQ LVQPSDIQLT YKNVLSYLNT LFIFQLKHHS 300
  301 KRNEVQEGSS EAFQQPLVLK GEMMPINDGN SIIFICSPHV TTVRDILNLK LYISDMPMHD 360
  361 ATRDLVMLNQ SRICQMELNK KLEETMKKMK KMTEELEVKK SQTDRLLFEF VPPVIAEALR 420
  421 AAKTVPAQEF SDCSVIFTDI PDFFTISVNC SPTEIITVVT DLFHRFDRII EKHKGYKVLS 480
  481 LMDSYLIVGG VPNANQYHCE DSLNLALGLL FEAKQVVVPK LERSVRLRIG VHCGPVVAGI 540
  541 VSQQKPRFCV LGNTVNVTKS ICSHSSPGKV LVSNAVRTMV TKHLKSIFVF NANGYLELQS 600
  601 GKVLTHFLEK NEKCSVWDIV DRDKATNDSI DGYRELHSDN GTEEWQEATV AAYRVISVVD 660
  661 ALENKQSRTR KALTRLRSVK RKFRTIQSND SGVSVSEPNV ESAVCSIM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] PSI-BLAST 41.522879 No description for 2o09A was found.
    2 View Details [181..422] PSI-BLAST 5.30103 No description for 2evaA was found.
    3 View Details [423..619] PSI-BLAST 49.69897 Crystal structure of a mutant form of the mycobacterial adenylyl cyclase Rv1625c
    4 View Details [620..708] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle