Protein Overview: PHIP_MOUSE

General Information:
Name(s) found:	PHIP_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|156633549\|sp\|Q8VDD9.2\|PHIP_MOUSE RecName: Full=PH-interacting protein; Short=PHIP; AltName: Full=IRS-1 PH domain-binding protein; AltName: Full=WD repeat-containing protein 11; AltName: Full=Neuronal differentiation-related protein; Short=NDRP [NCBI NR] PH-interacting protein OS=Mus musculus GN=Phip PE=1 SV=2 [Swiss-Prot] PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11) (Neuronal differentiation-related protein) (NDRP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Phip PH-interacting protein [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Phip PH-interacting protein ENSMUSG00000032253 IPI00311490 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00311490.4\|SWISS-PROT:Q8VDD9\|TREMBL:Q05BL7;Q05CQ5;Q32NY1;Q3UW86;Q8BRF9;Q8BSJ8\|ENSEMBL:ENSMUSP00000034787\|REFSEQ:NP_001074685 Tax_Id=10090 Gene_Symbol=Phip PH-interacting protein [ipi.MOUSE.fasta.20090209] PH-interacting protein OS=Mus musculus GN=Phip [011711_HMR.fasta] sp\|Q8VDD9\|PHIP_MOUSE PH-interacting protein OS=Mus musculus GN=Phip PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1821 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	regulation of protein amino acid phosphorylation [IDA] insulin receptor signaling pathway [IDA] negative regulation of apoptosis [IDA] positive regulation of cell proliferation [IMP] positive regulation of transcription [IDA] positive regulation of mitosis [IMP] positive regulation of insulin-like growth factor receptor signaling pathway [IDA]
Molecular Function:	protein binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRERKGLSE LRSELYFLIA RFLEDGPCQQ AAQVLIREVA EKELLPRRTD WTGKEHPRTY  60
   61 QNLVKYYRHL APDHLLQICH RLGPLLEQEI PQSVPGVQTL LGAGRQSLLR TNKSCKHVVW 120
  121 KGSALAALHC GRPPESPVNY GSPPSIADTL FSRKLNGKYR LERLVPTAVY QHMKMHKRIL 180
  181 GHLSSVYCVT FDRTGRRIFT GSDDCLVKIW ATDDGRLLAT LRGHAAEISD MAVNYENTMI 240
  241 AAGSCDKMIR VWCLRTCAPL AVLQGHSASI TSLQFSPLCS GSKRYLSSTG ADGTICFWLW 300
  301 DAGTLKINPR PTKFTERPRP GVQMICSSFS AGGMFLATGS TDHIIRVYFF GSGQPEKISE 360
  361 LEFHTDKVDS IQFSNTSNRF VSGSRDGTAR IWQFKRREWK SILLDMATRP AGQNLQGIED 420
  421 KITKMKVTMV AWDRHDNTVI TAVNNMTLKV WNSYTGQLIH VLMGHEDEVF VLEPHPFDPR 480
  481 VLFSAGHDGN VIVWDLARGV KVRSYFNMIE GQGHGAVFDC KCSPDGQHFA CTDSHGHLLI 540
  541 FGFGSSSKYD KIADQMFFHS DYRPLIRDAN NFVLDEQTQQ APHLMPPPFL VDVDGNPHPS 600
  601 RYQRLVPGRE NCREEQLIPQ MGVTSSGLNQ VLSQQANQDI SPLDSMIQRL QQEQDLRRSG 660
  661 EAGVSNASRV NRGSVSSTSE VHSPPNIGLR RSGQIEGVRQ MHSNAPRSEI ATERDLVAWS 720
  721 RRVVVPELSA GVASRQEEWR TAKGEEEIKS YRSEEKRKHL TVAKENKILT VSKNHAHEHF 780
  781 LDLGDSKKQQ ANQHNYRTRS ALEETPRPLE ELENGTSSSD EGEVLAVSGG TSEEEERAWH 840
  841 SDGSSSDYSS DYSDWTADAG INLQPPKKVP KHKTKKPESS SDEEEESENQ KQKHIKKERK 900
  901 KANEEKDGPT SPKKKKPKER KQKRLAVGEL TENGLTLEEW LPSAWITDTL PRRCPFVPQM 960
  961 GDEVYYFRQG HEAYVEMARK NKIYSINPKK QPWHKMELRE QELMKIVGIK YEVGLPTLCC1020
 1021 LKLAFLDPDT GKLTGGSFTM KYHDMPDVID FLVLRQQFDD AKYRPWNIGD RFRSVIDDAW1080
 1081 WFGTIESQEP LQPEYPDSLF QCYNVCWDNG DTEKMSPWDM ELIPNNAVFP EELGTSVPLT1140
 1141 DVECRSLIYK PLDGEWGANP RDEECERIVG GINQLMTLDI ASAFVAPVDL QAYPMYCTVV1200
 1201 AYPTDLSTIK QRLENRFYRR FSSLMWEVRY IEHNTRTFNE PGSPIVKSAK FVTDLLLHFI1260
 1261 KDQTCYNIIP LYNSMKKKVL SDSEEEEKDA DVPGTSTRKR KDHQPRRRLR NRAQSYDIQA1320
 1321 WKKQCQELLN LIFQCEDSEP FRQPVDLLEY PDYRDIIDTP MDFATVRETL EAGNYESPME1380
 1381 LCKDVRLIFS NFKAYTPSKR SRIYSMSLRL SAFFEEHISS VLSDYKSALR FHKRNTISKK1440
 1441 RKKRNRSSSL SSSAASSPER KKRILKPQLK SEVSTSPFSI PTRSVLPRHN AAQMNGKPES1500
 1501 SSVVRTRSNR VAVDPVVTEQ PSTSSATKAF VSKTNTSAMP GKAMLENSVR HSKALSTLSS1560
 1561 PDPLTFSHAT KNNSAKENME KEKPVKRKMK SSVFSKASPL PKSAAVIEQG ECKNNVLIPG1620
 1621 TIQVNGHGGQ PSKLVKRGPG RKPKVEVNTS SGEVTHKKRG RKPKNLQCAK QENSEQNNMH1680
 1681 PIRADVLPSS TCNFLSETNA VKEDLLQKKS RGGRKPKRKM KTHNLDSELI VPTNVKVLRR1740
 1741 SNRKKTDDPI DEEEEFEELK GSEPHMRTRN QGRRTAFYNE DDSEEEQRQL LFEDTSLTFG1800
 1801 TSSRGRVRKL TEKAKANLIG W

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.83

Protein Overview: PHIP_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: