Protein Overview: HRB1

General Information:
Name(s) found:	HRB1 / YNL004W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|154199622\|ref\|NP_014394.2\| Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p; Hrb1p [Saccharomyces cerevisiae] [NCBI NR] gi\|152031622\|sp\|P38922.2\|HRB1_YEAST RecName: Full=Protein HRB1; AltName: Full=Protein TOM34 [NCBI NR] Protein HRB1 OS=Saccharomyces cerevisiae GN=HRB1 PE=1 SV=2 [Swiss-Prot] Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p [SGD] HRB1 SGDID:S000004949, Chr XIV from 622917-622946,623289-624623, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] HRB1 SGDID:S000004949, Chr XIV from 622918-622947,623290-624624, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p" [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] [chemostatdb.fasta] Protein HRB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HRB1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] HRB1 SGDID:S000004949, Chr XIV from 622915-622944,623287-624621, Genome Release 64-1-1, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p" [yeast-030211-contam.fasta] HRB1 SGDID:S000004949, Chr XIV from 622915-622944,623287-624621, Genome Release 64-2-1, Verified ORF, "Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; HRB1 has a paralog, GBP2, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YNL004W SGDID:S000004949, Chr XIV from 622915-622944,623287-624621, Genome Release 64-1-1, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	454 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA] heterogeneous nuclear ribonucleoprotein complex [ISS][NAS]
Biological Process:	poly(A)+ mRNA export from nucleus [IPI]
Molecular Function:	RNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDQERGSEN NNRSRSRSRS PVRRRMSDDH GYERDNHLSR RSGNYNGRRK FADTYRGSRD  60
   61 RGEYRGGRER SDYRERERFN NRDNPRSRDR YDDRRRGRDV TGRYGNRRDD YPRSFRSRHN 120
  121 TRDDSRRGGF GSSGARGDYG PLLARELDST YEEKVNRNYS NSIFVGNLTY DSTPEDLTEF 180
  181 FSQIGKVVRA DIITSRGHHR GMGTVEFTNS DDVDRAIRQY DGAFFMDRKI FVRQDNPPPS 240
  241 NNIKERKALD RGELRHNRKT HEVIVKNLPA SVNWQALKDI FKECGNVAHA DVELDGDGVS 300
  301 TGSGTVSFYD IKDLHRAIEK YNGYSIEGNV LDVKSKESVH NHSDGDDVDI PMDDSPVNEE 360
  361 ARKFTENVVG GGERNRLIYC SNLPFSTAKS DLYDLFETIG KVNNAELRYD SKGAPTGIAV 420
  421 VEYDNVDDAD VCIERLNNYN YGGCDLDISY AKRL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	HRB1	Huh WK, et al. (2003)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HRB1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: