YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: FABB_ECOLI

General Information:
Name(s) found: FABB_ECOLI [Swiss-Prot]
Description(s) found:
SHOW ONLY BEST
  • gi|88192114|pdb|2AQB|D Chain D, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [NCBI NR]
  • gi|88192113|pdb|2AQB|C Chain C, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [NCBI NR]
  • gi|88192112|pdb|2AQB|B Chain B, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [NCBI NR]
  • gi|88192111|pdb|2AQB|A Chain A, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [NCBI NR]
  • gi|88192110|pdb|2AQ7|D Chain D, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [NCBI NR]
  • gi|88192109|pdb|2AQ7|C Chain C, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [NCBI NR]
  • gi|88192108|pdb|2AQ7|B Chain B, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [NCBI NR]
  • gi|88192107|pdb|2AQ7|A Chain A, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [NCBI NR]
  • gi|71159321|sp|P0A953.1|FABB_ECOLI RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 1; AltName: Full=3-oxoacyl-[acyl-carrier-protein] synthase I; AltName: Full=Beta-ketoacyl-ACP synthase I; Short=KAS I [NCBI NR]
  • gi|71042790|pdb|2BUI|D Chain D, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • gi|71042789|pdb|2BUI|C Chain C, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • gi|71042788|pdb|2BUI|B Chain B, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • gi|71042787|pdb|2BUI|A Chain A, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • gi|71042786|pdb|2BUH|D Chain D, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [NCBI NR]
  • gi|71042785|pdb|2BUH|C Chain C, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [NCBI NR]
  • gi|71042784|pdb|2BUH|B Chain B, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [NCBI NR]
  • gi|71042783|pdb|2BUH|A Chain A, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [NCBI NR]
  • pir||SYECA1 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) I - Escherichia coli (strain K-12) [NCBI NR]
  • pdb|1OG9|D Chain D, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • pdb|1OG9|C Chain C, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • pdb|1OG9|B Chain B, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • pdb|1OG9|A Chain A, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I In Complex With Octanoic Acid, 120k [NCBI NR]
  • pdb|1OG8|D Chain D, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I, 120 K [NCBI NR]
  • pdb|1OG8|C Chain C, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I, 120 K [NCBI NR]
  • pdb|1OG8|B Chain B, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I, 120 K [NCBI NR]
  • pdb|1OG8|A Chain A, E. Coli Beta-Ketoacyl [acyl Carrier Protein] Synthase I, 120 K [NCBI NR]
  • gi|1799716|dbj|BAA16180.1| 3-oxoacyl-[acyl-carrier-protein] synthase I [Escherichia coli W3110] [NCBI NR]
  • gi|163931084|pdb|2VBA|D Chain D, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Amino-Thiazole Inhibitor [NCBI NR]
  • gi|163931083|pdb|2VBA|C Chain C, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Amino-Thiazole Inhibitor [NCBI NR]
  • gi|163931082|pdb|2VBA|B Chain B, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Amino-Thiazole Inhibitor [NCBI NR]
  • gi|163931081|pdb|2VBA|A Chain A, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Amino-Thiazole Inhibitor [NCBI NR]
  • gi|163931080|pdb|2VB9|D Chain D, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli, Apo Structure [NCBI NR]
  • gi|163931079|pdb|2VB9|C Chain C, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli, Apo Structure [NCBI NR]
  • gi|163931078|pdb|2VB9|B Chain B, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli, Apo Structure [NCBI NR]
  • gi|163931077|pdb|2VB9|A Chain A, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli, Apo Structure [NCBI NR]
  • gi|163931076|pdb|2VB8|D Chain D, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Inhibitor Thiolactomycin [NCBI NR]
  • gi|163931075|pdb|2VB8|C Chain C, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Inhibitor Thiolactomycin [NCBI NR]
  • gi|163931074|pdb|2VB8|B Chain B, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Inhibitor Thiolactomycin [NCBI NR]
  • gi|163931073|pdb|2VB8|A Chain A, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli With Bound Inhibitor Thiolactomycin [NCBI NR]
  • gi|163931072|pdb|2VB7|D Chain D, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli, Apo Structure After Soak In Peg Solution [NCBI NR]
  • gi|163931070|pdb|2VB7|B Chain B, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli, Apo Structure After Soak In Peg Solution [NCBI NR]
  • gi|163931069|pdb|2VB7|A Chain A, Beta-Ketoacyl-Acp Synthase I (Kas) From E. Coli, Apo Structure After Soak In Peg Solution [NCBI NR]
  • gi|145884|gb|AAC67304.1| beta-ketoacyl-ACP synthase I [Escherichia coli] [NCBI NR]
  • gi|11513731|pdb|1G5X|D Chain D, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [NCBI NR]
  • gi|11513730|pdb|1G5X|C Chain C, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [NCBI NR]
  • gi|11513729|pdb|1G5X|B Chain B, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [NCBI NR]
  • gi|11513728|pdb|1G5X|A Chain A, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [NCBI NR]
  • gi|10120834|pdb|1FJ8|D Chain D, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [NCBI NR]
  • gi|10120833|pdb|1FJ8|C Chain C, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [NCBI NR]
  • gi|10120832|pdb|1FJ8|B Chain B, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [NCBI NR]
  • gi|10120831|pdb|1FJ8|A Chain A, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [NCBI NR]
  • gi|10120830|pdb|1FJ4|D Chain D, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [NCBI NR]
  • gi|10120829|pdb|1FJ4|C Chain C, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [NCBI NR]
  • gi|10120828|pdb|1FJ4|B Chain B, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [NCBI NR]
  • gi|10120827|pdb|1FJ4|A Chain A, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [NCBI NR]
  • 3-oxoacyl-[acyl-carrier-protein] synthase 1 (EC 2.3.1.41) (3-oxoacyl-[acyl-carrier-protein] synthase I) (Beta-ketoacyl-ACP synthase I) (KAS I) - Escherichia coli [Swiss-Prot]
  • 3-oxoacyl-[acyl-carrier-protein] synthase I [Escherichia coli K12]gi|26248711|ref|NP_754751.1| 3-oxoacyl-[acyl-carrier-protein] synthase I [Escherichia coli CFT073]gi|1788663|gb|AAC75383.1| 3-oxoacyl-[acyl-carrier-protein] synthase I [Escherichia coli K [nrdb_11152004_Chlamydomonas]
  • 3-oxoacyl-[acyl-carrier-protein] synthase 1 (3-oxoacyl-[acyl-carrier-protein] synthase I) (Beta-ketoacyl-ACP synthase I) (KAS I) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • Chain A, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [nr-271106-contam.fasta]
  • Chain A, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [nr-271106-contam.fasta]
  • Chain C, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [nr-271106-contam.fasta]
  • Chain B, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [nr-271106-contam.fasta]
  • Chain B, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [nr-271106-contam.fasta]
  • Chain C, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [nr-271106-contam.fasta]
  • Chain D, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [nr-271106-contam.fasta]
  • Chain C, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain B, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain D, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain B, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [nr-271106-contam.fasta]
  • Chain A, E. Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I, 120 K [nr-271106-contam.fasta]
  • Chain C, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [nr-271106-contam.fasta]
  • Chain A, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [nr-271106-contam.fasta]
  • Chain D, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain A, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain C, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [nr-271106-contam.fasta]
  • Chain B, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [nr-271106-contam.fasta]
  • Chain B, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [nr-271106-contam.fasta]
  • Chain C, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [nr-271106-contam.fasta]
  • beta-ketoacyl-ACP synthase I [Escherichia coli] [nr-271106-contam.fasta]
  • Chain C, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain D, E.Coli Beta-Ketoacyl (Acyl Carrier Protein) Synthase I In Complex With Octanoic Acid, 120k [nr-271106-contam.fasta]
  • Chain D, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [nr-271106-contam.fasta]
  • Chain A, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain A, Structure-Activity Relationships At The 5-Position Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherchia Coli [nr-271106-contam.fasta]
  • Chain D, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I [nr-271106-contam.fasta]
  • Chain B, The Structure Of Beta-Ketoacyl-[acyl Carrier Protein] Synthase I In Complex With Cerulenin, Implications For Drug Design [nr-271106-contam.fasta]
  • Chain D, Structure-Activity Relationships At The 5-Posiiton Of Thiolactomycin: An Intact 5(R)-Isoprene Unit Is Required For Activity Against The Condensing Enzymes From Mycobacterium Tuberculosis And Escherichia Coli [nr-271106-contam.fasta]
  • 3-oxoacyl-[acyl-carrier-protein] synthase 1 OS=Escherichia coli (strain K12) GN=fabB PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 406 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRAVITGLG IVSSIGNNQQ EVLASLREGR SGITFSQELK DSGMRSHVWG NVKLDTTGLI  60
   61 DRKVVRFMSD ASIYAFLSME QAIADAGLSP EAYQNNPRVG LIAGSGGGSP RFQVFGADAM 120
  121 RGPRGLKAVG PYVVTKAMAS GVSACLATPF KIHGVNYSIS SACATSAHCI GNAVEQIQLG 180
  181 KQDIVFAGGG EELCWEMACE FDAMGALSTK YNDTPEKASR TYDAHRDGFV IAGGGGMVVV 240
  241 EELEHALARG AHIYAEIVGY GATSDGADMV APSGEGAVRC MKMAMHGVDT PIDYLNSHGT 300
  301 STPVGDVKEL AAIREVFGDK SPAISATKAM TGHSLGAAGV QEAIYSLLML EHGFIAPSIN 360
  361 IEELDEQAAG LNIVTETTDR ELTTVMSNSF GFGGTNATLV MRKLKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..406] PSI-BLAST 123.0 Beta-ketoacyl-ACP synthase I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity, transferring acyl groups
    		•  4.09204107606289 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  3.79121338118181 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] synthase activity
    		•  3.71249191203055 bayes_pls_golite062009
  • C-acyltransferase activity
    		•  3.27532895419051 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.14957464437124 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.06879684191353 bayes_pls_golite062009
  • transferase activity
    		•  2.15834234036431 bayes_pls_golite062009
  • catalytic activity
    		•  2.14505178497871 bayes_pls_golite062009
  • acetyl-CoA C-acyltransferase activity
    		•  2.06897329929762 bayes_pls_golite062009
  • acetyl-CoA C-acetyltransferase activity
    		•  1.50839304016514 bayes_pls_golite062009
  • C-acetyltransferase activity
    		•  1.19264084089277 bayes_pls_golite062009
  • holo-[acyl-carrier-protein] synthase activity
    		•  0.800737755066121 bayes_pls_golite062009
  • fatty-acyl-CoA synthase activity
    		•  0.696028474623411 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  0.5334204157422 bayes_pls_golite062009
  • phosphotransferase activity, for other substituted phosphate groups
    		•  0.392307675469965 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.254850076259913 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle