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Protein Overview: EX3_ECOLI

General Information:
Name(s) found: EX3_ECOLI [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Exodeoxyribonuclease III (EC 3.1.11.2) (Exonuclease III) (EXO III) (AP endonuclease VI) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 268 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFVSFNING LRARPHQLEA IVEKHQPDVI GLQETKVHDD MFPLEEVAKL GYNVFYHGQK  60
   61 GHYGVALLTK ETPIAVRRGF PGDDEEAQRR IIMAEIPSLL GNVTVINGYF PQGESRDHPI 120
  121 KFPAKAQFYQ NLQNYLETEL KRDNPVLIMG DMNISPTDLD IGIGEENRKR WLRTGKCSFL 180
  181 PEEREWMDRL MSWGLVDTFR HANPQTADRF SWFDYRSKGF DDNRGLRIDL LLASQPLAEC 240
  241 CVETGIDYEI RSMEKPSDHA PVWATFRR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. EX3_ECOLI gi|134105085, gi... gi|189095939, gi...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..268] PSI-BLAST 69.69897 EXONUCLEASE III FROM ESCHERICHIA COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.13555370693179 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  2.05523724828257 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.05365635018354 bayes_pls_golite062009
  • hydrolase activity
    		•  1.91655065797595 bayes_pls_golite062009
  • exodeoxyribonuclease III activity
    		•  1.85973954222311 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  1.51772448052387 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  1.51551179681369 bayes_pls_golite062009
  • exonuclease activity
    		•  1.21933709871113 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.16071290518269 bayes_pls_golite062009
  • nuclease activity
    		•  0.48571734782839 bayes_pls_golite062009
  • binding
    		•  0.406311100383162 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle