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Protein Overview: EX1_ECOLI

General Information:
Name(s) found: EX1_ECOLI [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Exodeoxyribonuclease I (EC 3.1.11.1) (Exonuclease I) (DNA deoxyribophosphodiesterase) (dRPase) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 475 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNDGKQQST FLFHDYETFG THPALDRPAQ FAAIRTDSEF NVIGEPEVFY CKPADDYLPQ  60
   61 PGAVLITGIT PQEARAKGEN EAAFAARIHS LFTVPKTCIL GYNNVRFDDE VTRNIFYRNF 120
  121 YDPYAWSWQH DNSRWDLLDV MRACYALRPE GINWPENDDG LPSFRLEHLT KANGIEHSNA 180
  181 HDAMADVYAT IAMAKLVKTR QPRLFDYLFT HRNKHKLMAL IDVPQMKPLV HVSGMFGAWR 240
  241 GNTSWVAPLA WHPENRNAVI MVDLAGDISP LLELDSDTLR ERLYTAKTDL GDNAAVPVKL 300
  301 VHINKCPVLA QANTLRPEDA DRLGINRQHC LDNLKILREN PQVREKVVAI FAEAEPFTPS 360
  361 DNVDAQLYNG FFSDADRAAM KIVLETEPRN LPALDITFVD KRIEKLLFNY RARNFPGTLD 420
  421 YAEQQRWLEH RRQVFTPEFL QGYADELQML VQQYADDKEK VALLKALWQY AEEIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..475] PSI-BLAST 152.0 Exonuclease I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  2.30893115816458 bayes_pls_golite062009
  • ribonuclease activity
    		•  2.27368058469313 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.26022264830742 bayes_pls_golite062009
  • nuclease activity
    		•  1.81796593394339 bayes_pls_golite062009
  • endonuclease activity
    		•  1.79009816048707 bayes_pls_golite062009
  • exonuclease activity
    		•  1.64964907710028 bayes_pls_golite062009
  • catalytic activity
    		•  1.62277843225829 bayes_pls_golite062009
  • endoribonuclease activity
    		•  1.5391920929568 bayes_pls_golite062009
  • ribonuclease H activity
    		•  1.03274213246433 bayes_pls_golite062009
  • exodeoxyribonuclease I activity
    		•  0.70661333047946 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.63299586096139 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.62821439153618 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.1529022053594 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.0105328395026505 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle