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Protein Overview: ewg-PA, ewg-PC

General Information:
Name(s) found: ewg-PC / FBpp0100032 [FlyBase]
ewg-PA / FBpp0088457 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • The gene erect wing is referred to in FlyBase by the symbol Dmel\ewg (CG3114, FBgn0005427). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:162554..173667. It has the cytological map location 1A1. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; imaginal disc morphogenesis; muscle organ development. 72 alleles are reported. The phenotypes of these alleles are annotated with: dorsal medial muscle; wing; lateral oblique dorsal muscle. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
  • The gene erect wing is referred to in FlyBase by the symbol Dmel\ewg (CG3114, FBgn0005427). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:162554..173667. It has the cytological map location 1A1. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; imaginal disc morphogenesis; muscle organ development. 72 alleles are reported. The phenotypes of these alleles are annotated with: dorsal medial muscle; wing; lateral oblique dorsal muscle. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 733 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    Biological Process: muscle organ development [IMP][TAS]
    central nervous system development [IMP]
    imaginal disc morphogenesis [IMP]
    Molecular Function: DNA binding [ISS][NAS]
    specific RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTSYRLVV APAGSQRSST GNVVVTTTSS GSHSSNGANG GTGGTSAGSS TLGSGLNVTT  60
   61 ITATSGGQLQ SAGNTSQSNG TTYKIEMLEE DIQSLGSDDD DEDLISSDGS LYEGDLGSMP 120
  121 VNDDVAHQLA AAGPVGVAAA AAIASSKKRK RPHCFETNPS VRKRQQNRLL RKLRAIIYEF 180
  181 TGRVGKQAVV LVATPGKPNT SYKVFGAKPL EDVLRNLKNI VMDELDNALA QQAPPPPQDD 240
  241 PSLFELPGLV IDGIPTPVEK MTQAQLRAFI PLMLKYSTGR GKPGWGREST RPPWWPKELP 300
  301 WANVRMDARS EDDKQKISWT HALRKIVINC YKYHGREDLL PTFADDEDKV NALISQSGDE 360
  361 DEDMELSNPP TIHTVTTMTP PTGNSNQPQQ VNVVKINSAG TVITTHTAQS NTPAPTIIQS 420
  421 TNNQHVTTTA TLPASTKIEI CQAPAQNQQH HQHHQTHLPN AVHIQPVAGG QPQTIQLTTA 480
  481 SGTATATAVQ TTAAAVSAAQ AHAHSQSQAH SQSSANQTVT AQQIANAQVC IEPITLSDVD 540
  541 YTTQTVLSQN ADGTVSLIQV DPNNPIITLP DGTTAQVQGV ATLHQGEGGA TIQTVQSLTD 600
  601 VNGHENMTVD LTETQDGQIY ITTEDGQGYP VSVSNVISVP VSMYQSVMAN VQQIQTNSDG 660
  661 TVCLAPMQVE NGDQLETITM SPGMHQMMIQ GGPGQEPQLV QVVSLKDATL LSKAMEAINS 720
  721 GNVKSEDTII MEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] deduced N/A No confident structure predictions are available.
    2 View Details [92..335] MSA 1.019938 View MSA. No confident structure predictions are available.
    3 View Details [336..480] deduced N/A No confident structure predictions are available.
    4 View Details [481..658] MSA 1.179995 View MSA. No confident structure predictions are available.
    5 View Details [659..733] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle