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Protein Overview: EVGS_ECOLI

General Information:
Name(s) found: EVGS_ECOLI [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Sensor protein evgS precursor (EC 2.7.13.3) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 1197 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFLPYIFLL CCGLWSTISF ADEDYIEYRG ISSNNRVTLD PLRLSNKELR WLASKKNLVI  60
   61 AVHKSQTATL LHTDSQQRVR GINADYLNLL KRALNIKLTL REYADHQKAM DALAEGEVDI 120
  121 VLSHLVTSPP LNNDIAATKP LIITFPALVT TLHDSMRPLT SPKPVNIARV ANYPPDEVIH 180
  181 QSFPKATIIS FTNLYQALAS VSAGHNDYFI GSNIITSSMI SRYFTHSLNV VKYYNSPRQY 240
  241 NFFLTRKESV ILNEVLNRFV DALTNEVRYE VSQNWLDTGN LAFLNKPLEL TEHEKQWIKQ 300
  301 HPNLKVLENP YSPPYSMTDE NGSVRGVMGD ILNIITLQTG LNFSPITVSH NIHAGTQLSP 360
  361 GGWDIIPGAI YSEDRENNVL FAEAFITTPY VFVMQKAPDS EQTLKKGMKV AIPYYYELHS 420
  421 QLKEMYPEVE WIQVDNASAA FHKVKEGELD ALVATQLNSR YMIDHYYPNE LYHFLIPGVP 480
  481 NASLSFAFPR GEPELKDIIN KALNAIPPSE VLRLTEKWIK MPNVTIDTWD LYSEQFYIVT 540
  541 TLSVLLVGSS LLWGFYLLRS VRRRKVIQGD LENQISFRKA LSDSLPNPTY VVNWQGNVIS 600
  601 HNSAFEHYFT ADYYKNAMLP LENSDSPFKD VFSNAHEVTA ETKENRTIYT QVFEIDNGIE 660
  661 KRCINHWHTL CNLPASDNAV YICGWQDITE TRDLINALEV EKNKAIKATV AKSQFLATMS 720
  721 HEIRTPISSI MGFLELLSGS GLSKEQRVEA ISLAYATGQS LLGLIGEILD VDKIESGNYQ 780
  781 LQPQWVDIPT LVQNTCHSFG AIAASKSIAL SCSSTFPEHY LVKIDPQAFK QVLSNLLSNA 840
  841 LKFTTEGAVK ITTSLGHIDD NHAVIKMTIM DSGSGLSQEE QQQLFKRYSQ TSAGRQQTGS 900
  901 GLGLMICKEL IKNMQGDLSL ESHPGIGTTF TITIPVEISQ QVATVEAKAE QPITLPEKLS 960
  961 ILIADDHPTN RLLLKRQLNL LGYDVDEATD GVQALHKVSM QHYDLLITDV NMPNMDGFEL1020
 1021 TRKLREQNSS LPIWGLTANA QANEREKGLS CGMNLCLFKP LTLDVLKTHL SQLHQVAHIA1080
 1081 PQYRHLDIEA LKNNTANDLQ LMQEILMTFQ HETHKDLPAA FQALEAGDNR TFHQCIHRIH1140
 1141 GAANILNLQK LINISHQLEI TPVSDDSKPE ILQLLNSVKE HIAELDQEIA VFCQKND

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..289] PSI-BLAST 46.39794 No description for 2ia4A was found.
    2 View Details [290..537] FFAS03 7.28 Glutamine-binding protein
    3 View Details [538..677] PSI-BLAST 5.0 Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
    4 View Details [678..945] PSI-BLAST 46.221849 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    5 View Details [946..1079] PSI-BLAST 25.39794 No description for 2ayxA was found.
    6 View Details [1080..1197] PSI-BLAST 17.154902 No description for 2d1vA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.22974981386189 bayes_pls_golite062009
  • catalytic activity
    		•  1.01902493577147 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.16461666107495 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.13913685347546 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • DNA binding
    		•  0.73243452463464 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.6782569041078 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transcription factor activity
    		•  0.36759096137141 bayes_pls_golite062009
  • catalytic activity
    		•  0.285447488878019 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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