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Protein Overview: CE36943

General Information:
Name(s) found: CE36943 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00010456 status:Confirmed UniProt:Q21080 protein_id:CAA88854.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 499 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: isoleucine biosynthetic process [IEALink to PubMed article]
    tryptophan biosynthetic process [IEALink to PubMed article]
    threonine biosynthetic process [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    metabolic process [IEALink to PubMed article]
    cysteine biosynthetic process via cystathionine [IEALink to PubMed article]
    cysteine biosynthetic process from serine [IEALink to PubMed article]
    D-amino acid metabolic process [IEALink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    tryptophan synthase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    cystathionine beta-synthase activity [IEALink to PubMed article]
    amino acid binding [IEALink to PubMed article]
    threonine synthase activity [IEALink to PubMed article]
    cysteine synthase activity [IEALink to PubMed article]
    L-threonine ammonia-lyase activity [IEALink to PubMed article]
    D-serine ammonia-lyase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAPSRKKSI IHHHDHSHES TPQKTHHHRV KQAERKRTAS ISKEDGMEYN KRVRKLHKAF  60
   61 LTHGAESPHV DDKQTSGSNS DTEAPLFDPD CDPENPKKLK FSDISSAAFN IKNGVQTTPC 120
  121 VRSLQLSSKC EMDLYFKKEY LQVTGSFKER GARYALSKMA EQFKKAGVIA ASAGNHALAL 180
  181 SYHGQQMGIP VTVVMPVIAP LMKIQFCRSL GATVILKGES IAVAKDFALR HAKENHLKYI 240
  241 NGYDAIDILA GQGTIGLEIL DQVPDVDTIL VPVGGGGLIA GIATAVKTLK PDVHIYGIES 300
  301 ETCPSFTEAY EAGHIITSQA KASLADGLAV PTVGGNSLET AKGLVDKVIT VKEESIALSI 360
  361 LRLLEVEKAV VEGGGAVGLA AILEGKVPEL KGKKVVSILS GGNIDTTVLG RSIERGLAVD 420
  421 GRLVRLEVVV SDRPGGIAEL TTTIAHLGAS IKDIFHERAW ISTDVFHVKV KVVAETRGKE 480
  481 HVEEIETALK KIYDNVILH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] deduced N/A No confident structure predictions are available.
    2 View Details [98..419] PSI-BLAST 69.09691 Crystal Structure of S.pombe Serine Racemase
    3 View Details [420..499] PSI-BLAST 91.69897 THREONINE DEAMINASE (BIOSYNTHETIC) FROM E. COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • threonine racemase activity
    		•  4.44340924206787 bayes_pls_golite062009
  • threonine synthase activity
    		•  3.59927532963055 bayes_pls_golite062009
  • cysteine synthase activity
    		•  3.57860549303214 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  3.33109959091277 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.99526226543975 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • binding
    		•  0.507026774040034 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle